2012 Fiscal Year Final Research Report
Basic research on regeneration medicine to cleft lip and/or palate patients using human mesenchymal stem cells.
| Project/Area Number |
22592223
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Saga University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
GOTO Masaaki 佐賀大学, 医学部, 教授 (10145211)
NOGUCHI Nobuhiro 佐賀大学, 医学部, 講師 (40284658)
DANJO Atsushi 佐賀大学, 医学部, 助教 (80452712)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 再生医学 / 間葉系幹細胞 / 口唇口蓋裂 |
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| Research Abstract |
We discovered the tiny population of undifferentiated cells in surgical specimens from patients with cleft lip and/or palate. They have potential to promote the regeneration. They can differentiate into osteoblasts, adipocyte and chondrocyte, like as bone marrow stem cells and dental pulp stem cells. Our data demonstrate that the mesenchymal stem cells may provide therapeutic benefits for treating cleft lip and/or palate patients. Stem cell based therapy holds great promise for establishing such a multifaceted therapeutic strategy.
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