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2012 Fiscal Year Final Research Report

Regeneration of salivary gland by autologous cell transplantation

Research Project

  • PDF
Project/Area Number 22592224
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Surgical dentistry
Research InstitutionKumamoto University

Principal Investigator

HIRAKI Akimitsu  熊本大学, 大学院・生命科学研究部, 講師 (60404034)

Co-Investigator(Kenkyū-buntansha) SHINOHARA Masanori  熊本大学, 大学院・生命科学研究部, 教授 (90117127)
Project Period (FY) 2010 – 2012
Keywords唾液腺 / 再生・医学 / 細胞・組織 / 発生・分化
Research Abstract

We isolated monoclonal mouse epithelial salivary gland cells by original medium. By usingthe cells, we identified important factor associated differentiation induction ofbidimensionally. Moreover we tried regeneration of the gland three-dimensionally. As aresult, they indicated that HGF and type IV collagen play an important role in 3Dregeneration of the salivary gland. To reveal its mechanism, we need further study

  • Research Products

    (3 results)

All 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results)

  • [Journal Article] Histopathological Changes in Parotidand Submandibular Glands of PatientsTreated with Preoperative ChemoradiationTherapy for Oral Cancer2012

    • Author(s)
      Keiko TESHIMA, Ryuji MURAKAMI, RyojiYOSHIDA, Hideki NAKAYAMA, Akimitsu HIRAKI,Toshinori HIRAI, Yuji NAKAGUCHI, NaokoTSUJITA, Etsushi TOMITAKA, MitsuhiroFURUSAWA, Yasuyuki YAMASHITA, MasanoriSHINOHARA
    • Journal Title

      Journal of Radiation Research

      Volume: 53(3) Pages: 492-496

    • Peer Reviewed
  • [Presentation] 口腔癌の化学放射線療法における唾液変化と口腔粘膜炎に関する検討2013

    • Author(s)
      竹下尚志、吉田遼司、平木昭光、高尾直宏、川原健太、中川純泰、永田将士、田中拓也、中山秀樹、篠原正徳
    • Organizer
      第31回日本口腔腫瘍学会総会
    • Place of Presentation
      秋葉原コンベンションホール東京
    • Year and Date
      20130124-0125
  • [Presentation] 唾液腺腫瘍 98 例の臨床統計的検討2013

    • Author(s)
      吉田遼司、平木昭光、中山秀樹、丸瀬靖之、永田将士、田中拓也、川原健太、中川純泰、廣末晃之、吉武義泰、太田和俊、篠原正徳
    • Organizer
      第31回日本口腔腫瘍学会総会
    • Place of Presentation
      秋葉原コンベンションホール東京
    • Year and Date
      20130124-0125

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Published: 2014-08-29  

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