2012 Fiscal Year Final Research Report
Regeneration of salivary gland by autologous cell transplantation
| Project/Area Number |
22592224
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Kumamoto University |
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Principal Investigator |
HIRAKI Akimitsu 熊本大学, 大学院・生命科学研究部, 講師 (60404034)
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| Co-Investigator(Kenkyū-buntansha) |
SHINOHARA Masanori 熊本大学, 大学院・生命科学研究部, 教授 (90117127)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 唾液腺 / 再生・医学 / 細胞・組織 / 発生・分化 |
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| Research Abstract |
We isolated monoclonal mouse epithelial salivary gland cells by original medium. By usingthe cells, we identified important factor associated differentiation induction ofbidimensionally. Moreover we tried regeneration of the gland three-dimensionally. As aresult, they indicated that HGF and type IV collagen play an important role in 3Dregeneration of the salivary gland. To reveal its mechanism, we need further study
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Research Products
(3 results)
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[Journal Article] Histopathological Changes in Parotidand Submandibular Glands of PatientsTreated with Preoperative ChemoradiationTherapy for Oral Cancer2012
Author(s)
Keiko TESHIMA, Ryuji MURAKAMI, RyojiYOSHIDA, Hideki NAKAYAMA, Akimitsu HIRAKI,Toshinori HIRAI, Yuji NAKAGUCHI, NaokoTSUJITA, Etsushi TOMITAKA, MitsuhiroFURUSAWA, Yasuyuki YAMASHITA, MasanoriSHINOHARA
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Journal Title
Journal of Radiation Research
Volume: 53(3)
Pages: 492-496
Peer Reviewed
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