2012 Fiscal Year Final Research Report
Influence of oral malodor compounds for expression of cancer-related gene in oral epidermal cells.
| Project/Area Number |
22592349
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Tsurumi University (2011-2012)
The Nippon Dental University (2010) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SATO Tsutomu 日本歯科大学東京短期大学, 歯科衛生学 科, 教授 (60130671)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 癌関連遺伝子 / 硫化水素 / 歯肉癌細胞 / アポトーシス / PHLDA1 |
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| Research Abstract |
Ca9-22 cells that highly express pleckstrin homology-like domain, family A, member 1 (PHLDA1) are susceptible to H2S-induced apoptosis. PHLDA1 in oral cancer cells plays a role in apoptosis suppression, and PHLDA1 may be a marker of apoptosis susceptibility.
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