Development of high precision 3D radiation treatment planning system based on similar cases

2012 Fiscal Year Final Research Report

• Project/Area Number: 22611011
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Medical Physics/Radiological Technology
• Research Institution: Kyushu University
• Principal Investigator: ARIMURA Hidetaka 九州大学, 医学研究院, 保健学部門 (20287353)
• Co-Investigator(Kenkyū-buntansha): 中村 和正 九州大学, 大学病院, 准教授 (20284507)
• Co-Investigator(Renkei-kenkyūsha): 塩山 善之 九州大学, 医学研究院, 教授 (10323304)
• Project Period (FY): 2010 – 2012
• Keywords: 治療計画 / 類似症例検索 / 画像処理

Research Abstract

The purpose of this study was to develop a computer-aided method for determination of beam arrangements based on similar cases in a radiotherapy treatment-planning database for stereotactic lung radiation therapy. First, the five most similar cases were searched, based on geometrical features related to the location, size and shape of the planning target volume, lung and spinal cord. Second, five beam arrangements of an objective case were automatically determined by registering five similar cases with the objective case, with respect to lung regions, by means of a linear registration technique. The most usable beam arrangement was selected by sorting the five treatment plans based on eight plan evaluation indices, including the D95, mean lung dose and spinal cord maximum dose. We applied the proposed method to 10 test cases, by using an RTPdatabase of 81 cases with lung cancer, and compared the eight plan evaluation indices between the original treatment plan and the corresponding most usable similar-case-based treatment plan. As a result, the proposed method may provide usable beam arrangements, which have no statistically significant differences from the original beam arrangements (P > 0.05) in terms of the eight plan evaluation indices. Therefore, the proposed method could be employed as an educational tool for less experienced treatment planners.

Research Products

• [Journal Article] 豊福不可依,放射線治療におけるelectronic portal imaging device を用いた4次元線量分布推定法の開発 (2013)
  • Author(s): 溝口明日実, 有村秀孝, 塩山善之, 廣瀬貴章, 穴井重男, 本田浩, 梅津芳幸, 平田秀紀, 大喜雅文, 中村和正
  • Journal Title: 電子情報通信学会 医用画像特集 Volume: Vol.J96-D,No.4 Pages: 813-823
  • Peer Reviewed
• [Journal Article] Computer-aided beam arrangement based on similar cases in radiation treatment planning databases for stereotactic lung radiation therapy. (2013)
  • Author(s): Magome T, Arimura H, Shioyama Y, Mizoguchi A, Tokunaga C, Nakamura K, Honda H, Ohki M, Toyofuku F, Hirata H.
  • Journal Title: Journal of Radiation Research Volume: Vol. 54
  • Peer Reviewed
• [Journal Article] Computerized estimation of patient setup errors in portal images based on localized pelvic templates for prostate cancer radiotherapy (2012)
  • Author(s): Arimura H, Itano W, Shioyama Y, Matsushita N, Magome T, Yoshitake T, Anai S, Nakamura K, Yo s hid o me S, Yamagami A, Honda H, Ohki M, Toyofuku F, Hirata H.
  • Journal Title: Journal of Radiation Research Volume: 53(6) Pages: 961-72
  • Peer Reviewed
• [Journal Article] Hayabuchi N.,Automated Estimation of Number of Implanted Iodine-125 Seeds for Prostate Brachytherapy based on Two-View Analysis of Pelvic Radiographs (2012)
  • Author(s): Kawata H, Arimura H, Suefuji H, Ohkura S, Saida Y, Nashiki K, Hayashida K, Kawahara T, Ohishi A
  • Journal Title: Journal of Radiation Research Volume: 53(5) Pages: 742-52
  • Peer Reviewed
• [Journal Article] Esophageal Stenosis Associated with Tumor Regression in Radiation Therapy for Esophageal Cancer:Frequency and Prediction (2012)
  • Author(s): Atsumi K, Shioyama Y, Arimura H, Terashima K, Matsuki T, Ohga S, Yoshitake T, Nonoshita T, Tsurumaru D, Ohnishi K, Asai K, Matsumoto K, Nakamura K, Honda H.
  • Journal Title: International Journal of Radiation Oncology, Biology, Physics Volume: 82(5) Pages: 1973-80
  • Peer Reviewed
• [Journal Article] Estimation of focal and extra-focal radiation profiles based on Gaussian modeling in medical linear accelerators (2011)
  • Author(s): Anai S, Arimura H, Nakamura K, Ar aki F, Matsuki T, Yoshikawa H, Yoshidome S, Shioyama Y, Honda H, Ikeda N.
  • Journal Title: Radiological Physics and Technology Volume: 4(2) Pages: 173-9
  • Peer Reviewed
• [Journal Article] 肺定位放射線治療におけるEPIDシネ画像を用いた腫瘍位置のずれ量自動推定方法の開発 (2011)
  • Author(s): 吉留 郷志, 有村 秀孝, 塩山 善之, 中村和正, 穴井重男, 中村浩太, 野元諭, 本田 浩, 豊福不可依, 寺嶋廣美, 平田秀紀
  • Journal Title: 医学物理 Volume: Vol.30, No.3 Pages: 120-131
  • Peer Reviewed
• [Presentation] Optimization method of beam directions based on similar cases in stereotactic body radiotherapy for lung cancers (2013)
  • Author(s): Taiki Magome, Hidetaka Arimura, Yoshiyuki Shioyama, Asumi Mizoguchi, Katsumasa Nakamura, Yasuhiko Nakamura, Hiroshi Honda, Masafumi Ohki, Fukai Toyofuku, Hideki Hirata
  • Organizer: 第105回日本医学物理学会学術大会
  • Place of Presentation: 横浜
  • Year and Date: 2013-04-13
• [Presentation] Computer-Assisted Particle Therapy System Based on Computational Anatomy Models for Treatment Planning (2013)
  • Author(s): Hidetaka Arimura
  • Organizer: Computational Anatomy for Computer-aided Diagnosis and Therapy
  • Place of Presentation: Osaka University
  • Year and Date: 2013-02-23
• [Presentation] 類似症例に基づくビームアングルの最適化方法の開発 (2012)
  • Author(s): 馬込大貴,有村秀孝,塩山善之,溝口明日実,徳永千晶,中村和正,本田浩,中村泰彦,豊福不可依,平田秀紀
  • Organizer: 日本放射線腫瘍学会第25回学術大会
  • Place of Presentation: 東京
  • Year and Date: 2012-11-23
• [Presentation] Computer-assisted determination of the usable beam arrangement from similar treatment plans in stereotactic body radiotherapy (p.101-107),Workshop of Image-Guidance and Multimodal Dose Planning in Radiation Therapy (2012)
  • Author(s): Magome T, Arimura H, Shioyama Y, Mizoguchi A, Tokunaga C, Nakamura K, Nakamura Y, Honda H, Ohki, Toyofuku F, Hirata H.
  • Organizer: MICCAI 2012
  • Place of Presentation: Nice
  • Year and Date: 2012-10-05
• [Presentation] ComputationalImage-Assisted Radiation Treatment Planning (2012)
  • Author(s): Arimura H, Jin Z, Kakiuchi G, Magome T, ShioyamaY, Nakamura K.
  • Organizer: Progress in Radiology 2012
  • Place of Presentation: Tokyo
  • Year and Date: 2012-09-07
• [Presentation] Similar-case-based optimization of beam arrangements in stereotactic body radiation therapy (2012)
  • Author(s): Magome T, Arimura H, Shioyama Y, Mizoguchi A, Tokunaga C, Nakamura K, Honda H, Ohki, Toyofuku F, Hirata H.
  • Organizer: AAPM2012
  • Place of Presentation: Charlott
  • Year and Date: 2012-07-31
• [Presentation] 肺定位放射線治療計画支援のための類似症例に基づくビーム方向自動決定法の開発 (2012)
  • Author(s): 馬込大貴,有村秀孝,塩山善之,溝口明日実,徳永千晶,中村和正,本田 浩,大喜雅文,豊福不可依,平田秀紀
  • Organizer: 第103回日本医学物理学会学術大会
  • Place of Presentation: 横浜
  • Year and Date: 2012-04-14
• [Presentation] Computer-assisted radiation treatment planning system for determination of beam directions based on similar cases in a database for stereotactic body radiotherapy (2012)
  • Author(s): Magome T, Arimura H, Shioyama Y, Mizoguchi A, Tokunaga C, Nakamura K, Honda H, Ohki M, Toyofuku F, Hirata H.
  • Organizer: SPIE Medical Imaging 2012
  • Place of Presentation: San Diego
  • Year and Date: 2012-02-07
• [Presentation] 放射線治療計画支援のための類似症例を用いたビーム方向決定法の開発 (2012)
  • Author(s): 馬込大貴,有村秀孝,塩山善之,徳永千晶,中村和正,本田 浩,大喜雅文,豊福不可依,平田秀紀
  • Organizer: メディカルイメージング連合フォーラム
  • Place of Presentation: 沖縄
  • Year and Date: 2012-01-19
• [Presentation] 肺定位放射線治療における類似症例を用いたビームアングルの自動決定法 (2011)
  • Author(s): 馬込大貴,有村秀孝,塩山善之,徳永千晶,中村和正,穴井重男,本田 浩,大喜雅文,豊福不可依,平田秀紀
  • Organizer: 第24回日本放射線腫瘍学会(JASTRO)
  • Place of Presentation: 神戸
  • Year and Date: 2011-11-19
• [Presentation] Automated Determination of Beam Arrangement Based on Similar Cases in Radiotherapy Treatment Planning Database for Lung Stereotactic Body Radiotherapy (2011)
  • Author(s): Magome T, Arimura H, Shioyama Y, Tokunaga C, Nakamura K, Anai S, Honda H, Ohki M, Toyofuku F, Hirata H.
  • Organizer: ASTRO 2011
  • Place of Presentation: Miami Beach
  • Year and Date: 2011-10-05
• [Presentation] Automated method for determination of beam directions based on similar cases for lung stereotactic body radiotherapy. (2011)
  • Author(s): Magome T, Arimura H, Shioyama Y, Tokunaga C, Nakamura K, Honda H, Ohki M, Hirata H, Toyofuku F.
  • Organizer: 6th Japan-Korea Joint Meeting on Medical Physics (JKMP), 11th Asia-Oceania Congress of Medical Physics(AOCMP)
  • Place of Presentation: Fukuoka
  • Year and Date: 2011-10-01
• [Book] Analysis for Assisting Radiation Oncologists' Decision Making in Radiation Treatment Planning," (2013)
  • Author(s): Arimura H, Magome T, Kakiuchi G, Kuwazuru J, Mizoguchi A
  • Total Pages: 30
  • Publisher: The University of Chicago
• [Remarks] 研究者のホームページで研究成果を,英語と日本語で以下のURLで公開している.
  • URL: http://www.shs.kyushu-u.ac.jp/~arimura
• [Patent(Industrial Property Rights)] 放射線ビームアングル決定システム,放射線ビームアングル決定方法及び放射線ビームアングル決定用コンピュータプログラム (2012)
  • Inventor(s): 有村秀孝,馬込大貴,塩山善之
  • Industrial Property Rights Holder: 九州大学
  • Industrial Property Number: 特願2012-69606号
  • Filing Date: 2012-03-26