2011 Fiscal Year Final Research Report
Development of a cell microarray chip for evaluating invasion of cancer cells by transfer printing of transfected cells
| Project/Area Number |
22656189
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 細胞マイクロアレイ / 癌細胞 / 浸潤 / 細胞転写 / PEG脂質 / コラーゲンシート |
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| Research Abstract |
We developed a method that can print a microarray of transfected cells from a glass substrate onto a hydrogel, and by using this method, microarrays of transfected cancer cells were successfully prepared in a three-dimensional extracellular matrix gel and employed for evaluating the anti-invasion activities of siRNA under an in vivo-like environment.
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