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2011 Fiscal Year Final Research Report

The Development of a rapid genetic diagnostic system and the application to the definitive diagnosis of influenza subtypes

Research Project

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Project/Area Number 22659118
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Laboratory medicine
Research Institution財団法人東京都医学総合研究所 (2011)
Tokyo Metropolitan Organization for Medical Research (2010)

Principal Investigator

NAITO Akihiro  財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員 (20332372)

Co-Investigator(Kenkyū-buntansha) SAKURAI Akira  財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員 (40546628)
Co-Investigator(Renkei-kenkyūsha) NOMURA Namiko  財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究補助員 (50599694)
Project Period (FY) 2010 – 2011
Keywords臨床検査システム / 遺伝子診断 / 新型インフルエンザ
Research Abstract

Usually, it takes longer than two hours for the definitive diagnosis of the subtypes of influenza viruses by conventional real time PCRs. This newly developed system, however, enables to genotype of influenza viruses in clinical samples in less than 30 min. for whole processes starting from RNA extraction. Although the specificity of the system was slightly lower than that of conventional real time PCRs, it is suggested that the new system is able to identify H1N1 or H3N2 and oseltamivir(Tamiflu) susceptible or resistant in the clinical samples.

  • Research Products

    (1 results)

All 2010

All Presentation (1 results)

  • [Presentation] 高速・高感度インフルエンザ診断法の開発2010

    • Author(s)
      内藤暁宏・野村奈美子・櫻井陽・南波玲子・森實芳仁・芝崎太
    • Organizer
      Cell Biology Summer Meeting 2010
    • Place of Presentation
      箱根
    • Year and Date
      2010-07-03

URL: 

Published: 2013-07-31  

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