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2012 Fiscal Year Final Research Report

Development of two dimensional beam monitor using position sensitive gas detector for accelerator-based neutron capture therapy

Research Project

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Project/Area Number 22680044
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Medical systems
Research InstitutionKyoto University

Principal Investigator

TANAKA Hiroki  京都大学, 原子炉実験所, 助教 (70391274)

Project Period (FY) 2010 – 2012
Keywords中性子捕捉療法 / 加速器中性子源 / 二次元中性子モニタ / リアルタイムモニタ
Research Abstract

At Kyoto University Research Reactor Institute, accelerator based epithermal neutron source have developed for boron neutron capture therapy. The sufficient epithermal neutron intensity was successfully obtained for the first in the world. It is desired that the treatment beam should be evaluate, because the characteristics is different from the reactor based neutron source that have been used clinical studies. In this study, the real-time beam monitor using position sensitive gas detector that has the sensitivity of fast and thermal neutron was successfully developed.

  • Research Products

    (20 results)

All 2013 2012 2011 2010 Other

All Journal Article (9 results) Presentation (11 results)

  • [Journal Article] Radiosensitivity of pimonidazole-unlabelled intratumour quiescent cell population to γ-rays, accelerated carbon ion beams and boron neutron capture reaction, S.-I2013

    • Author(s)
      Masunaga, Y. Sakurai, H. Tanaka, et al
    • Journal Title

      British Journal of Radiology

      Volume: 86(1021) Pages: 20120302

    • DOI

      DOI:10.1259/bjr.20120302

  • [Journal Article] Reirradiation for locally recurrent lung cancer in the chest wall with boron neutron capture therapy (BNCT): A case report2012

    • Author(s)
      M. Suzuki, O. Suzuki, Y. Sakurai, H. Tanaka,et al
    • Journal Title

      International Cancer Conference Jounal

      Volume: 2012(1) Pages: 235-238

    • DOI

      DOI10.1007/s13691-012-0048-8

  • [Journal Article] Evaluating the Usefulness of a Novel 10B-Carrier Conjugated With Cyclic RGD Peptide in Boron Neutron Capture Therapy,S.-I2012

    • Author(s)
      Masunaga,S. Kimura,T. Harada,K. Okuda,Y. Sakurai,H. Tanaka,et al
    • Journal Title

      World J Oncol

      Volume: 3(3) Pages: 103-112

    • DOI

      DOI:10.4021/wjon477w

  • [Journal Article] Effects of employing a 10B-carrier and manipulating intratumour hypoxia on local tumour response and lung metastatic potential in boron neutron capture therapy,S.-I2012

    • Author(s)
      Masunaga, Y. Sakurai, H. Tanaka, et al
    • Journal Title

      British Journal of Radiology

      Volume: 85(1011) Pages: 249-258

    • DOI

      DOI:10.1259/bjr/20974899

  • [Journal Article] Experimental Verification of Beam Characteristics for Cyclotron-based Epithermal Neutron Source (C-BENS)2011

    • Author(s)
      H. Tanaka, et al
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 69(12) Pages: 1642-1645

    • DOI

      DOI:10.1016/j.apradiso.2011.03.020

  • [Journal Article] The optimization study of Bonner sphere in the epi-thermal neutron irradiation field for BNCT2011

    • Author(s)
      H. Ueda, H. Tanaka, et al
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 69(12) Pages: 1657-1659

    • DOI

      DOI:10.1016/j.apradiso.2011.01.034

  • [Journal Article] A phantom experiment for the evaluation of whole body exposure during BNCT using cyclotron-based epithermal neutron source(C-BENS)2011

    • Author(s)
      T. Tsukamoto, H. Tanaka, et al.
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 69(12) Pages: 1830-1833

    • DOI

      DOI:10.1016/j.apradiso.2011.03.013

  • [Journal Article] Evaluation for activities of component of Cyclotron-Based Epithermal Neutron Source(C-BENS) and the surface of concrete wall in irradiation room2011

    • Author(s)
      M. Imoto, H. Tanaka, et al.
    • Journal Title

      M. Imoto, H. Tanaka, et al.

      Volume: 69(12) Pages: 1646-1648

    • DOI

      DOI:10.1016/j.apradiso.2011.03.018

  • [Journal Article] Study on optimization of multi ionization-chamber system for BNCT2011

    • Author(s)
      T. Fujii, H. Tanaka, et al
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 69(12) Pages: 1862-1865

    • DOI

      DOI:10.1016/j.apradiso.2011.03.031

  • [Presentation] Development of two dimensional thermal neutron flux monitor using multi-wire proportional counter for boron neutron capture therapy2012

    • Author(s)
      H. Tanaka et al
    • Organizer
      Development of two dimensional thermal neutron flux monitor using multi-wire proportional counter for boron neutron capture therapy
    • Place of Presentation
      Anaheim, USA
    • Year and Date
      20121029-1103
  • [Presentation] 中性子捕捉療法のためのマルチワイヤ検出器を用いた二次元中性子検出器の開発2012

    • Author(s)
      田中浩基 他
    • Organizer
      日本原子力学会 2012年秋の年会
    • Place of Presentation
      広島
    • Year and Date
      20120919-21
  • [Presentation] Evaluation of thermal neutron irradiation field using cyclotron based neutron source for alphaautoradiography2012

    • Author(s)
      H. Tanaka et al
    • Organizer
      15th International Congress on Neutron Capture Therapy
    • Place of Presentation
      つくば
    • Year and Date
      20120909-14
  • [Presentation] Study on dose evaluation at irradiation room using cyclotron based epithermal neutron source for boron neutron capture therapy2012

    • Author(s)
      H. Tanaka et al
    • Organizer
      12th International Conference on Radiation Shielding
    • Place of Presentation
      奈良
    • Year and Date
      20120902-07
  • [Presentation] BNCTのための石英ファイバーを用いた熱中性子モニタアレイによる二次元検出器の開発2012

    • Author(s)
      田中浩基 他
    • Organizer
      2012年春季第59回応用物理学関係連合講演会
    • Place of Presentation
      早 稲田
    • Year and Date
      2012-03-16
  • [Presentation] Development of thermal neutron flux monitor using small scintillator array coupled with quartz fibers for Boron Neutron Capture Therapy2011

    • Author(s)
      H. Tanaka et al
    • Organizer
      2011 IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Place of Presentation
      Valencia, Spain
    • Year and Date
      20111023-29
  • [Presentation] 京都大学原子炉実験所におけるBNCT用サイクロトロンを用いた熱外中性子源の概要2011

    • Author(s)
      田中浩基 他
    • Organizer
      日本原子力学会2011年秋の年会
    • Place of Presentation
      北九州
    • Year and Date
      2011-09-21
  • [Presentation] Development of a Neutron Flux Monitor Using a Small Scintillator Coupled with Quartz Fiber for a Cyclotron-Based Boron Neutron Capture Therapy2010

    • Author(s)
      H. Tanaka et. al
    • Organizer
      2011 IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Place of Presentation
      Knoxville, USA
    • Year and Date
      20101031-1106
  • [Presentation] 石英ファイバーとシンチレータを 用いた中性子捕捉療法用中性子モニタの開発2010

    • Author(s)
      田中浩基 他
    • Organizer
      原子力学会2010年秋の大会
    • Place of Presentation
      北海道
    • Year and Date
      20100915-17
  • [Presentation] サイクロトロンベース熱外中性子源のマイクロドシメトリを用いた線質評価2010

    • Author(s)
      田中浩基 他
    • Organizer
      第7回日本中性子捕捉療法学会
    • Place of Presentation
      学習院大
    • Year and Date
      20100805-06
  • [Presentation] Beam property of intense epithermal neutron source based on Be(p,n) reaction using cyclotron accelerator for boron neutron capture therapy

    • Author(s)
      H. Tanaka et. al
    • Organizer
      第49回粒子線治療世界会議
    • Place of Presentation
      前橋

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Published: 2014-08-29  

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