2011 Fiscal Year Final Research Report
Value coding of the striatal neurons
| Project/Area Number |
22700424
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | National Institute of Radiological Sciences |
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Principal Investigator |
MINAMIMOTO Takafumi 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, チームリーダー (50506813)
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| Research Collaborator |
HORI Yukiko 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 博士研究員 (30433246)
BARRY J Richmond 米国国立衛生研究所(NIH), NIMH・Laboratory of Neuropsychology, 部門チーフ
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| Project Period (FY) |
2010 – 2011
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| Keywords | システム神経生理 / ニューロインフォマティクス |
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| Research Abstract |
We studied how caudate neurons code temporal discounted values in an instrumental task. We recorded the 99 phasically active neurons in the caudate nucleus. Sixty-four neurons showed significant cue-related activity. 15 neurons(23%) showed significant linear relation with discounted outcome value(DV). Within 120 trials recording periods, more than 15% of motivational value was discounted as reward accumulation(i. e., devaluation). However, the DV related activity was not sensitive to this reward devaluation. These results suggest that a subset of single caudate neuron represent the discounted outcome value computed from the predicted reward size and delay duration. The caudate discounted value coding is insensitive to devaluation. These value coding appears to be involved in value based decision making rather than motivational regulation of action.
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