2012 Fiscal Year Final Research Report
Changes in muscle reflex after stroke and the effectsof exercise training
| Project/Area Number |
22700536
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Hiroshima University |
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Principal Investigator |
LIANG Nan 広島大学, 大学院・医歯薬保健学研究院, 助教 (70512515)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 中枢運動指令 / 運動昇圧反射 / 脳血管疾患 / 脳血管疾患 / 高血圧 / 神経科学 / 生理学 / リハビリテーション |
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| Research Abstract |
The present study aimed to explore the central and peripheral modulations of the cardiovascular response to exercise in hypertension, which is a key factor in central nervous system disorders. The pressor responses to activation of the central command and peripheral muscle reflex were greater in spontaneously hypertensive rats in comparison with those in normotensive rats. Furthermore, by stimulating the peripheral sensory afferents the pressor response to central command was attenuated in normotensive but not hypertensive rats. These findings suggest that the interactive relationship between central command and the muscle reflex is altered in hypertension and thereby mediates, in part, the exaggerated cardiovascular response to exercise in this disease.
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[Presentation] 高血圧における運動時の中枢性循環調節2012
Author(s)
Nan Liang, Masaki Mizuno, Ryan Downey, Jere H Mitchell, Scott A Smith
Organizer
循環生理機能と病態に関するHiroshimaシンポジウム
Place of Presentation
広島
Year and Date
2012-08-25
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