2012 Fiscal Year Final Research Report

The search for original protein and biokinetics of antihypertensive peptide derived from Jellyfish Stomolophus nomurai

Research Project

Project/Area Number	22700735
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Eating habits, studies on eating habits
Research Institution	Aomori University of Health and Welfare
Principal Investigator	MORINAGA Yae 青森県立保健大学, 健康科学部, 助教 (40404818)
Research Collaborator	MATSUE Hajime 青森県立保健大学, 健康科学部, 教授 (30106843) IWAI Kunihisa 青森県立保健大学, 健康科学部, 教授 (80404812) TOMITA Hidehiro 青森県産業技術センター, 下北ブランド研究所, 研究開発部長 UCHISAWA Hidemitsu 青森県工業総合研究センター, 環境技術研究部, 部長 NARAOKA Tetsushi 青森県工業総合研究センター, 企画経営, 担当
Project Period (FY)	2010 – 2012
Keywords	食素材
Research Abstract	I found the antihypertensive peptide YYAPFE derived from Jellyfish Stomolophus nomurai. The peptide has not a characteristic triple-helical conformation of collagen that is derived from the [Gly-X-Y]n sequence. Therefore, the original protein of the peptide was estimated to be non-collagen protein. Furthermore, I searched long chain peptide derived from non-collagen protein. A new nonadecapeptide was identified as NKPLAGSPAASELYTEAGG. However, the peptide has not ACE inhivitory activity.