2012 Fiscal Year Final Research Report
Preparation of desmosines for diagnosis of COPD by the biomarker
| Project/Area Number |
22710224
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Living organism molecular science
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| Research Institution | Sophia University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | COPD / エラスチン / バイオマーカー / クロスカップリング |
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| Research Abstract |
In this study, total synthesis of desmosine and isodesmosine, knownas COPD biomarkers and elastin crosslinkers, was achieved via palladium-catalyzedcross-coupling reactions as key steps.
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