2011 Fiscal Year Final Research Report
Mammalian viviparity developed by retrotransposon-derived gene, Peg10
| Project/Area Number |
22770004
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Genetics/Genome dynamics
|
|---|
| Research Institution | Tokyo Medical and Dental University |
|---|
Principal Investigator |
ONO Ryuichi 東京医科歯科大学, 難治疾患研究所, 助教 (10401358)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Keywords | レトロトランスポゾン / 胎盤 |
|---|
| Research Abstract |
I have previously demonstrated that Peg10, a paternally expressed imprinted gene, is derived from retrotransposon and has an essential function in placental development. To reveal the function of Peg10, I established TS(Trophoblast Stem) cell lines from Peg10 KO mice. By comparing the gene expressionbetween Peg10 KO TS cell lines and wild type TS cell lines, I identified Peg10 down regulated genes and Peg10 binding DNA sequence.
|
-
[Journal Article] Identification of tammar wallaby SIRH12, derivedfrom a marsupial-specific retrotransposition event2011
Author(s)
Ono, R., Kuroki, Y., Naruse, M., Ishii, M., Iwasaki, S., Toyoda, A., Fujiyama, A., Shaw, G., Renfree, MB., Kaneko-Ishino, T., Ishino, F
-
Journal Title
DNA Research
Volume: 18(4)
Pages: 211-219
-
-
-
-
-
-
-
-
