2011 Fiscal Year Final Research Report

The analysis of recognition of pathogen infection and induction of hypersensitive reaction by plant receptor-type protein kinases

Research Project

Project/Area Number	22780088
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Applied biochemistry
Research Institution	Tokyo Medical and Dental University
Principal Investigator	SAWANO Yoriko 東京医科歯科大学, 教養部, 准教授 (00571077)
Project Period (FY)	2010 – 2011
Keywords	受容体型キナーゼ / 植物病原菌 / エリシター / X線結晶構造解析 / 核磁気共鳴解析 / 相互作用解析
Research Abstract	Plants recognize molecules derived from pathogen, elicitor, and cause hypersensitive response(HR) as one of protective reaction against pathogen. Plant cysteine-rich receptor-like kinases have been reported to relate the induction of HR, and its recognition mechanim of pathogen was analyzed in this study. A candidate for elicitor, interacted with CRK, was found in yeast homogenate, and 3-D structure of CRK was solved by X-ray crystallography and the interaction site of CRK was identified by nuclear magnetic resonance spectroscopy.

(3 results)