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2011 Fiscal Year Final Research Report

The analysis of recognition of pathogen infection and induction of hypersensitive reaction by plant receptor-type protein kinases

Research Project

  • PDF
Project/Area Number 22780088
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Applied biochemistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

SAWANO Yoriko  東京医科歯科大学, 教養部, 准教授 (00571077)

Project Period (FY) 2010 – 2011
Keywords受容体型キナーゼ / 植物病原菌 / エリシター / X線結晶構造解析 / 核磁気共鳴解析 / 相互作用解析
Research Abstract

Plants recognize molecules derived from pathogen, elicitor, and cause hypersensitive response(HR) as one of protective reaction against pathogen. Plant cysteine-rich receptor-like kinases have been reported to relate the induction of HR, and its recognition mechanim of pathogen was analyzed in this study. A candidate for elicitor, interacted with CRK, was found in yeast homogenate, and 3-D structure of CRK was solved by X-ray crystallography and the interaction site of CRK was identified by nuclear magnetic resonance spectroscopy.

  • Research Products

    (3 results)

All 2012 2011

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Book (1 results)

  • [Journal Article] Crystallization and preliminary X-ray crystallographic analysis of dioscorin from Dioscorea japonica2012

    • Author(s)
      Xue YL, Miyakawa T, Sawano Y, Tanokura M.
    • Journal Title

      Acta Crystallogr Sect F Struct Biol Cryst Commun

      Volume: Vol.68(Pt2) Pages: 193-195

    • Peer Reviewed
  • [Journal Article] Cloning of genes and enzymatic characterizations of novel dioscorin isoforms from Dioscorea japonica2012

    • Author(s)
      Xue YL, Miyakawa T, Sawano Y, Tanokura M.
    • Journal Title

      Plant Sci.

      Volume: Vol.183 Pages: 14-19

    • Peer Reviewed
  • [Book] Nuts and Seeds in Health and Disease Prevention2011

    • Author(s)
      Hatano K, Miyakawa T, Sawano Y, and Tanokura M
    • Total Pages
      527-534
    • Publisher
      Academic Press

URL: 

Published: 2013-07-31  

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