2011 Fiscal Year Final Research Report
Generation of mice containing only paternal genome
| Project/Area Number |
22780257
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Hokkaido University |
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Principal Investigator |
OTSUKA Saori 北海道大学, 獣医学研究科, 特任助教 (10566152)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 形態 / MRL/MpJマウス / 精巣内卵細胞 / 性分化 / 減数分裂 / 生殖腺 / 生殖細胞 |
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| Research Abstract |
The testicular oocyte-producing pathway has at least 2 responsible genes, one on Chromosome Y and the other on autosome. The autosomal causative genes are suggested to be homozygous recessive. In addition, some XY primordial germ cells located in the vicinity of the rete testis or at the cranial edge of the fetal testis enter meiosis from E12. 5-14. 5 and differentiate as oocytes.
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