Anti-EGFR antibody conjugated gold liposome for molecular imaging and therapy on NSCLC cells

2012 Fiscal Year Final Research Report

• Project/Area Number: 22790770
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Respiratory organ internal medicine
• Research Institution: Tokyo Medical University
• Principal Investigator: YOKOYAMA Tomohisa 東京医科大学, 医学部, 講師 (40408240)
• Project Period (FY): 2010 – 2012
• Keywords: 非小細胞肺癌 / ナノ粒子 / DDS(drug delivery system) / オートファジー

Research Abstract

In the present study, we investigated in vitro effect of these liposomes on EGFR-expressing/-null NSCLC cells. Our findings demonstrated that EGFR-targeted liposome is a promising agent for therapy and molecular imaging of NSCLC

Research Products

• [Presentation] EGFR-targeted gold liposome for molecular imaging and therapy on NSCLC cells. (2012)
  • Author(s): Yokoyama T, Osato Y, Miyazawa K, Hayabe H, Miyasato A, Nomura M, Gotoh N, Itoi T, Tauchi T, Ikeda N, Ohyashiki K
  • Organizer: AACR 103th Annual meeting 2012
  • Place of Presentation: Chicago USA
  • Year and Date: 20120331-0404
• [Presentation] Anti-EGFR antibody conjugated gold liposome for molecular imaging and therapy on NSCLC cells (2011)
  • Author(s): Yokoyama T, Miyazawa K, Nomura M, Gotoh N, Ohyashiki K
  • Organizer: 第49回日本癌学会学術集会
  • Place of Presentation: 名古屋
  • Year and Date: 20111003-05