2011 Fiscal Year Final Research Report
Induction of chronic metal allergy and participate in intrinsic atopic dermatitis.
| Project/Area Number |
22791096
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dermatology
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
MORI Tomoko 産業医科大学, 医学部, 非常勤医師 (80399203)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 金属アレルギー / 内因性アトピー性皮膚炎 |
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| Research Abstract |
Two types of atopic dermatitis(AD) have been proposed, the extrinsic tyoe shows high IgE levels and the intrinsic type exhibits normal IgE levels. Because I understood that the positive percentage of the metal patch test was high in intrinsic AD. I made the allergy to metal onset model mouse. However, I performed reexamination pro-experiment because individual difference was big, and the mice which were not established had much sensitization. I examined the laboratory procedure of the allergy to metal afterwards.
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