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2011 Fiscal Year Final Research Report

Development of the diagnostic procedure of the pervasive developmental disorder using the near-infrared spectroscopy

Research Project

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Project/Area Number 22791109
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionThe University of Tokyo

Principal Investigator

KUWABARA Hitoshi  東京大学, 医学部附属病院, 助教 (50456117)

Project Period (FY) 2010 – 2011
Keywords精神生理学 / 広汎性発達障害
Research Abstract

We compared 42 healthy control group and schizophrenia group which matched age, with 42 patients with PDD using the 52 channels NIRS instrument(ETG4000). We used a word fluency task for a cognitive activation, and analyzed mean change of the oxy-hemoglobin concentration during the task. About each measurement of 52 channels, we conducted the one-way analysis of variance between three groups. Activation was significantly smaller in PDD group and schizophrenia group than the healthy control group in Ch1 and Ch29. Activation was significantly larger than schizophrenia group in the healthy control group and PDD group in Ch14, Ch25, Ch36, and Ch46. Activation was significantly smaller in schizophrenia group than the healthy control group in Ch28.

  • Research Products

    (2 results)

All 2011

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (1 results)

  • [Journal Article] Developmental changes of prefrontalactivation in humans a near-infraredspectroscopy study of preschool childrenand adults2011

    • Author(s)
      Kawakubo Y, Kono T, Takizawa R, KuwabaraH, Ishii-Takahashi A, Kasai K
    • Journal Title

      PLoS One

      Volume: 6 Pages: e25944

    • Peer Reviewed
  • [Presentation] 自閉症スペクトラム障害家系の全エクソン解析2011

    • Author(s)
      桑原斉
    • Organizer
      第52回日本児童青年期精神医学会
    • Place of Presentation
      徳島県徳島市
    • Year and Date
      2011-11-11

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Published: 2013-07-31   Modified: 2015-12-16  

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