2012 Fiscal Year Final Research Report
Clarification of oxygen sensor system of the mouse trachea epithelia
Project/Area Number |
22791598
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Otorhinolaryngology
|
Research Institution | Osaka University |
Principal Investigator |
ISHIDA Yusuke 大阪大学, 医学系研究科, 講師 (30381809)
|
Project Period (FY) |
2010 – 2012
|
Keywords | 酸素センサー / 低酸素 / 味蕾様構造物 / 気管上皮 / in situ hybridization |
Research Abstract |
Oxygen is essential for life, however, oxygen sensor and the transmission system are still unknown. We hypothesized that oxygen is sensed on trachea epithelia and began to research on oxygen-sensing system of the mouse trachea epithelia. Our results indicated that taste bud-like structure in the trachea epithelia is oxygen sensor. Furthermore, it was indicated that ATP and ATP receptor play crucial roles on oxygen-sensing systems of the mouse trachea epithelia.
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Research Products
(3 results)