2011 Fiscal Year Final Research Report
Quantitative analysis and the investigation of the pneumococcal nasopharyngeal colonization in children.
| Project/Area Number |
22791623
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Wakayama Medical University |
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Principal Investigator |
OGAMI Masashi 和歌山県立医科大学, 医学部, 博士研究員 (90423946)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 鼻科学 |
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| Research Abstract |
Streptococcus pneumonia(S. pneumoniae) colonized in nasopharynx of children is an important pathogenic bacteria in pediatric acute otitis media and rhinosinusitis. In this study, we performed quantitative analysis of nasopharyngeal S. pneumonia by using real-time PCR method. In the healthy children, the concentration of S. pneumoniae showed an inverse relation with the age. On the other hands, the concentration of S. pneumoniae in the children with upper respiratory infection was higher than the healthy children. Moreover, we revealed that a new rapid antigen test for detection of pneumococci in middle ear fluids and nasopharyngeal secretions can be an available tool for detection S. pneumoniae.
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