2011 Fiscal Year Final Research Report
The evaluation of the marker genes during the development of trabecular meshwork cells and the induction of trabecular meshwork cells from human iPS cells
| Project/Area Number |
22791678
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Ophthalmology
|
|---|
| Research Institution | Kyoto Prefectural University of Medicine |
|---|
Principal Investigator |
UENO Morio 京都府立医科大学, 医学研究科, 助教 (40426531)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Keywords | 眼発生 / 再生医学 |
|---|
| Research Abstract |
Transplantation of trabecular meshwork cells to the damaged trabecular meshwork tissues in patients of primary open angle glaucoma because one of causes of primary open angle glaucoma is the decrement of trabecular meshwork cells. In this study, we performed the development of the induction system of human trabecular meshwork cells from human induced pluripotent stem cells to mimic the in vivo development of trabecular meshwork tissues.
|
-
[Journal Article] Common variants in CDKN2B-AS1 associated with optic-nerve vulnerability of glaucoma identified by genome-wide association studies in Japanese2012
Author(s)
Nakano M, Ikeda Y, Tokuda Y, Fuwa M, Omi N, Ueno M, Imai K, Adachi H, Kageyama M, Mori K, Kinoshita S, Tashiro K
-
Journal Title
PLoS One
Volume: 7(3)
Pages: e33389
-
-
-
[Journal Article] Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells2010
Author(s)
Ohgushi M, Matsumura M, Eiraku M, Murakami K, Aramaki T, Nishiyama A, Muguruma K, Nakano T, Suga H, Ueno M, Ishizaki T, Suemori H, Narumiya S, Niwa H, Sasai Y
-
Journal Title
Cell Stem Cell
Volume: 7(2)
Pages: 225-39
-
-
-
-
-
-
-
-
-
-
-
-
-
