2011 Fiscal Year Final Research Report

Identification and characterization of the surface proteins in periodontal pathogens

Research Project

Project/Area Number	22791772
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Morphological basic dentistry
Research Institution	Kagoshima University
Principal Investigator	OOGAI Yuichi 鹿児島大学, 医歯学総合研究科, 助教 (40511259)
Project Period (FY)	2010 – 2011
Keywords	歯周病原因菌 / 外膜タンパク / 補体抵抗性
Research Abstract	Our research has been focused on identification and virulence of surface protein in periodontal pathogens. We did not find the novel virulence factor in surface proteins of Fusobacteriu nucleatum. The cells of F. nucleatum are fusiform rods. We found that this morphology formation was involved in two autotransporter proteins found in outer membrane proteins of F. nucleatum. We also found that complement resistance of Tannerella forsythia was involved in S-layer composed from two high molecular weight proteins.

(1 results)