2011 Fiscal Year Final Research Report

Pathology of burning mouth syndrome : The change of the autonomic nerve functions.

Research Project

Project/Area Number	22791961
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Surgical dentistry
Research Institution	Tokyo Medical and Dental University
Principal Investigator	NIIMI Tomoko (TAKAHASHI Tomoko) 東京医科歯科大学, 歯学部附属病院, 医員 (50510351)
Project Period (FY)	2010 – 2011
Keywords	歯科麻酔学
Research Abstract	Burning mouth syndrome(BMS) is a disease characterized by the chronic burning pain in the oral region. The etiology is not clear. I examined association between heart autonomic nerve activity and BMS by the heart rate variability analysis in 2010. I reported that there was no significant association in CVRR, LF, HF, TF, and LF/HF. Recent studies have reported that BMS must be concerned with psychological factors. Therefore I examined the association between multiple psychological tests and BMS in 2011. I used SDS, TMI, and STAI for the tests. Only SDS showed significant association with BMS in 3 tests by the simple comparison between BMS group and control group. Age, sex, and SDS showed significant association by the multiplex logistic analysis. In conclusion, depression may have influence on BMS. In future, more stable results will be obtained when I increase the study patients.