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2011 Fiscal Year Final Research Report

The role of autophagy in a tooth development

Research Project

  • PDF
Project/Area Number 22792052
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Orthodontic/Pediatric dentistry
Research InstitutionOkayama University

Principal Investigator

YANAGITA Takeshi  岡山大学, 岡山大学病院, 助教 (90534793)

Project Period (FY) 2010 – 2011
Keywordsオートファジー / 発生 / 歯 / 骨組織
Research Abstract

This study is to be clear the role of autophagy in the process of hard tissue development, especially tooth. At first, we found the difference between tooth development of wild type mouse and that of ATG5 KO(autophagy blocked) mice.
In other hand, we also noticed that the influence of autophagy is larger in bone tissue development rather than tooth development in my experiment process. These results were presented on academic journals and meetings.

  • Research Products

    (6 results)

All 2012 2011

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (2 results)

  • [Journal Article] Roles of heparan sulfate sulfation in dentinogenesis2012

    • Author(s)
      S Hayano, H Kurosaka, T Yanagita(他10人、3番目)
    • Journal Title

      JBC

      Volume: (in press)

    • Peer Reviewed
  • [Journal Article] Stage-specific embryonic antigen-4 identifies human dental pulp stem cells2012

    • Author(s)
      N Kawanabe, S Murata, T Yanagita(他9人、5番目)
    • Journal Title

      Experimental cell research

      Volume: 318 Pages: 1247-1255

    • Peer Reviewed
  • [Journal Article] Core Binding Factor Beta Functions in the Maintenance of Stem Cells and Orchestrates Continuous Proliferation and Differentiation in Mouse Incisors2011

    • Author(s)
      H Kurosaka, Md. N Islam, T Yanagita(他10人、7番目)
    • Journal Title

      STEM CELLS

      Volume: 29 Pages: 1792-1803

    • Peer Reviewed
  • [Journal Article] lass III malocclusion with complex problems of lateral open bite and severe crowding successfully treated with miniscrew anchorage and lingual orthodontic brackets2011

    • Author(s)
      T Yanagita, S Kuroda, T Takano-Yamamoto, T Yamashiro
    • Journal Title

      Am J Orthod Dentofac Orthop

      Volume: 139 Pages: 679-689

    • Peer Reviewed
  • [Presentation] 象牙質形成におけるWntシグナリングとヘパラン硫酸の糖残基修飾2011

    • Author(s)
      早野暁
    • Organizer
      第70回日本矯正歯科学会
    • Place of Presentation
      愛知
    • Year and Date
      20111017-20
  • [Presentation] 骨形成におけるオートファジーの関与2011

    • Author(s)
      中村政裕
    • Organizer
      先端歯学スクール
    • Place of Presentation
      神奈川
    • Year and Date
      2011-09-01

URL: 

Published: 2013-07-31  

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