Modeling and experimental analysis of Gene Regulatory Networks of the ascidian CNS

2011 Fiscal Year Final Research Report

• Project/Area Number: 22870018
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Developmental biology
• Research Institution: Kyoto University
• Principal Investigator: SATOU Kaoru 京都大学, 大学院・理学研究科, 助教 (00447921)
• Project Period (FY): 2010 – 2011
• Keywords: 転写 / ネットワーク

Research Abstract

Systematic gene disruption assays by morpholino oligonucleotide injection provided gene circuit diagrams for each cells in the Ascidian CNS. Based on this gene regulatory network, I constructed a model for the mechanism of transcription in Ascidian CNS.

Research Products

• [Journal Article] Development (2010)
  • Author(s): Kubo, A., Suzuki, N. Xuayang, Yuan. Nakai, K. Satoh, N. Imai, K. S. and Satou, Y.
  • Journal Title: the company of biologists Volume: 137 Pages: 1613-1623
  • DOI: DOI:10.1242/dev.046789
  • Peer Reviewed
• [Presentation] Pinhead functions as a negative regulator of ADMPin Ciona intestinalis (2011)
  • Author(s): Imai, K. S. and Satou, Y. Pinhead
  • Organizer: 第82回日本動物学会
  • Place of Presentation: 旭川
  • Year and Date: 2011-09-21
• [Presentation] Pinhead functions as a negative regulator of ADMPin Ciona intestinalis (2011)
  • Author(s): Imai, K. S. and Satou, Y. Pinhead
  • Organizer: 2nd joint meeting of the French and British Societies for Developmental Biology
  • Place of Presentation: ニース
  • Year and Date: 2011-09-04
• [Presentation] Pin functions as a negative regulator of BMP signaling (2011)
  • Author(s): Imai, K. S
  • Organizer: The 4th International Symposium of the Biodiversity and Evolution Global COE project
  • Place of Presentation: 京都
  • Year and Date: 2011-07-09