2011 Fiscal Year Final Research Report
The association between ADH7 polymorphisms and alcohol consumption
| Project/Area Number |
22890250
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Hygiene
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| Research Institution | Aichi Cancer Center Research Institute |
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Principal Investigator |
OZE Isao 愛知県がんセンター(研究所), 疫学・予防部, 任意研修生 (00584509)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 疫学 / ゲノム |
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| Research Abstract |
ADH1B and ADH1C gene polymorphisms, rs1229984 and rs1693482 are associated with alcohol drinking habit and esophageal cancer risk, through modulating catalytic activity of ADH enzymes. However, there were few evidences about the association between other five ADHs and alcohol drinking. We investigated ADH gene polymorphisms and alcohol drinking habit of 4062 subjects. Rs1154460, the loci on ADH7 had significant association with alcohol drinking.
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Research Products
(3 results)
