• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2022 Fiscal Year Annual Research Report

Platform of Supporting Cohort Study and Biospecimen Analysis

Research Project

Project/Area Number 22H04923
Research InstitutionThe University of Tokyo

Principal Investigator

村上 善則  東京大学, 医科学研究所, 教授 (30182108)

Co-Investigator(Kenkyū-buntansha) 若井 建志  名古屋大学, 医学系研究科, 教授 (50270989)
村山 繁雄  大阪大学, 大学院連合小児発達学研究科, 特任教授(常勤) (50183653)
醍醐 弥太郎  東京大学, 医科学研究所, 客員教授 (30345029)
中村 洋子  千葉県がんセンター(研究所), がん予防センター, 主任上席研究員 (60260254)
成松 宏人  地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所がん予防・情報学部(遺伝診療科), 部長 (50524419)
栗木 清典  静岡県立大学, 食品栄養科学部, 教授 (20543705)
鈴木 貞夫  名古屋市立大学, 医薬学総合研究院(医学), 教授 (20226509)
松尾 恵太郎  愛知県がんセンター(研究所), がん予防研究分野, 分野長 (80393122)
喜多 義邦  敦賀市立看護大学, 看護学部, 教授 (30147524)
三浦 克之  滋賀医科大学, 医学部, 教授 (90257452)
小山 晃英  京都府立医科大学, 医学(系)研究科(研究院), 講師 (40711362)
有澤 孝吉  徳島大学, 大学院医歯薬学研究部(医学域), 教授 (30203384)
村田 昌之  九州大学, 大学病院, 講師 (60380622)
田中 恵太郎  佐賀大学, 医学部, 教授 (50217022)
郡山 千早  鹿児島大学, 医歯学域医学系, 教授 (30274814)
玉腰 暁子  北海道大学, 医学研究院, 教授 (90236737)
今田 恒夫  山形大学, 医学部, 教授 (60333952)
武林 亨  慶應義塾大学, 医学部(信濃町), 教授 (30265780)
鈴木 康司  藤田医科大学, 保健学研究科, 教授 (60288470)
齊藤 祐子  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 (60344066)
高尾 昌樹  国立研究開発法人国立精神・神経医療研究センター, 病院 臨床検査部, 部長 (50245487)
金田 大太  医療法人さわらび会福祉村病院長寿医学研究所, 神経病理研究所, 副所長 (40564795)
美原 盤  公益財団法人脳血管研究所, その他部局等, 研究員(移行) (30190721)
井本 逸勢  愛知県がんセンター(研究所), 研究所長, 研究所長 (30258610)
宮城 洋平  地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所, 所長 (00254194)
渡邉 俊樹  聖マリアンナ医科大学, 医学研究科, 教授 (30182934)
安井 寛  東京大学, 医科学研究所, 特任准教授 (40448593)
中杤 昌弘  名古屋大学, 医学系研究科(保健), 准教授 (10559983)
清水 厚志  岩手医科大学, 医歯薬総合研究所, 教授 (30327655)
室谷 健太  久留米大学, 付置研究所, 教授 (10626443)
Project Period (FY) 2022-04-01 – 2028-03-31
Keywords生体試料支援 / コホート / 臨床検体 / 一般健常人 / 大規模ゲノム解析・オミックス解析
Outline of Annual Research Achievements

総括支援班:若手支援研究成果発表会を3年ぶりに対面で開催し、20名の若手研究者の成果発表・情報交換を実施した(2/21)。また日本疫学会学術総会での自由集会開催、日本癌学会等のランチョンセミナー、展示会出展、関連分野の科研費取得者へのメール送信等、積極的広報活動を展開した。
コホートによるバイオリソース支援班:コホート研究のデータ・生体試料の提供などにより、163件の研究支援を実施した。支援基盤の整備では、主要な基盤であるJ-MICC研究において、従来の死亡・がん罹患追跡データ、第二次調査データに加え、循環器疾患罹患データの整備にも着手した。またSNPアレイによるタイピングデータの拡大を図った。
ブレインリソースの整備と活用支援班:日本神経科学ブレインバンクネットワーク大阪大学拠点は献脳リソース構築を神戸に拡大、司法解剖レジストリに若年コントロールを追加した。高齢者ブレインバンクは国立精神・神経研究センターとコロナ死後脳リソース構築を開始、福祉村とネットCPC教育配信を行った。リソース提供で、国際一流紙の多数の成果発表に貢献した。
生体試料支援班:380課題に生体機能分子の高感度解析・技術支援と連携構築支援を実施した。151課題にがん関連試料・情報を提供し、病理解析支援を実施した。24,294試料(血液、リンパ球、組織、DNA)を収集し、2,853試料を提供した。解析・連携構築、試料支援の体制を強化し、ヒト生体試料の活用研究の啓発を行った。
バイオメディカルデータ解析支援班:大規模オミクスデータ解析支援、医療ビッグデータ解析支援により、15件の研究支援を実施した。1/16-20には昨年度に続き第7回遺伝統計セミナーをオンラインで開催し、全国から74名の参加登録を得た。また、3/2に第1回リアルワールドデータ研究のための統計学セミナーをオンラインで開催し、492名の参加登録を得た。

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

総括支援班:広報活動を積極的に展開した。即ち、日本分子生物学会ほか9学会への展示会ブース出展、日本生化学会大会ほか4学会でランチョンセミナーを開催したほか、これまでCoBiAの支援を受けた5人の研究者に対しインタビューし、成果を記事や動画にまとめてホームページに掲載するなど、広く本支援の周知活動を行った。
コホートによるバイオリソース支援班:Webページからの研究支援申請、毎月末の締め切り、申請課題の審査、支援実施の流れが機能しつつあり、論文採択に結びついている。またJ-MICC研究による支援において、第二次調査データの活用が開始され、幅広い研究テーマへの対応が可能になった。
ブレインリソースの整備と活用支援班:コロナによる剖検数激減を、生前献脳同意登録と構築支援出張により補えた。Global Neuro CPCネット発信で、全国の臨床・基礎神経科学研究者の教育に貢献した。本支援でのプリオン病サーベイランスと同じ診断基準でのリソース提供の独自性と優秀性で、Nature誌、Cell誌等の多数の研究発表に貢献した。
生体試料支援班:高精度分子解析技術支援の強化、生体試料バンクの連携施設追加による体制整備、組織標本の収集体制の強化と支援内容・成果の広報・啓発を進めつつ、生体機能分子解析・技術・連携支援および生体試料収集・提供支援の支援課題数は令和3年度の研究支援実施計画を上回り、国際的にインパクトのある学術発表に貢献した。
バイオメディカルデータ解析支援班:当班は令和4年度から新たに立ち上げ、知名度が充分でない状況にあったが、15件の支援依頼を受け支援を実施できた。遺伝統計セミナーは今回7回目の開催にもかかわらず昨年度以上の参加が確認された。リアルワールドデータ研究のための統計学セミナーは初めての開催にもかかわらず492名というCoBiAでもこれまでにない規模の参加登録があった。

Strategy for Future Research Activity

総括支援班:引き続き各種学会展示会への出展、各種セミナー、成果発表会等を開催することで、支援事業の周知活動を行うとともに研究者間の連携、人材育成のさらなる強化を図っていく。また利用料徴取についても継続して検討する。
コホートによるバイオリソース支援:支援件数の増加を図るため、関連分野の研究室および科研費研究代表者へのダイレクトメール、関係学会のメーリングリスト等で支援活動の広報を行う。支援の主要な基盤であるJ-MICC研究(参加者数10.6万人)について、虚血性心疾患・脳卒中罹患データ、SNPアレイデータを整備し、データを順次、支援に活用する。さらにJ-MICC研究以外のコホートに基づく支援を促進する。
ブレインリソースの整備と活用支援班:全身剖検を基盤とする脳・脊髄・末梢組織リソースの構築、臨床症状・放射線画像・バイオリソースとの統合、免疫組織化学・超微形態・凍結脳ウエスタンブロット・ゲノム解析による診断、日本神経病理学会認定医制度との連携に基づく若手神経病理医育成支援、リソース構築・運用に基づく神経科学者への下支えを全国レベルで展開する。
生体試料支援班:急速に多様化する生命科学研究の動向と生命科学研究者のニーズに対応するため、最新の分子解析支援技術の導入・強化を進め、高品質で多彩なヒト試料の収集・提供を進める。研究支援分担・連携機関の連携を強化し、先駆的な共同研究の構築支援を行い、生命科学研究者向けのヒト生体試料を用いた研究の啓発活動を展開する。
バイオメディカルデータ解析支援班:令和4年度に続き、大規模オミクスデータ解析支援、医療ビッグデータ解析支援による研究支援を実施する。遺伝統計セミナーとリアルワールドデータ研究のための統計学セミナーを令和5年度も開催する。遺伝統計セミナーは対面での開催も検討する。

  • Research Products

    (320 results)

All 2023 2022 Other

All Int'l Joint Research (6 results) Journal Article (168 results) (of which Int'l Joint Research: 48 results,  Peer Reviewed: 164 results,  Open Access: 109 results) Presentation (142 results) (of which Int'l Joint Research: 21 results,  Invited: 24 results) Remarks (2 results) Patent(Industrial Property Rights) (2 results) (of which Overseas: 1 results)

  • [Int'l Joint Research] Harvard Medical School/Stanford University/National Institutes of Health(米国)

    • Country Name
      U.S.A.
    • Counterpart Institution
      Harvard Medical School/Stanford University/National Institutes of Health
    • # of Other Institutions
      42
  • [Int'l Joint Research] University of Cambridge/University College London/Institute of Cancer Research(英国)

    • Country Name
      UNITED KINGDOM
    • Counterpart Institution
      University of Cambridge/University College London/Institute of Cancer Research
    • # of Other Institutions
      8
  • [Int'l Joint Research] McGill University/University of Toronto/BC Cancer(カナダ)

    • Country Name
      CANADA
    • Counterpart Institution
      McGill University/University of Toronto/BC Cancer
    • # of Other Institutions
      3
  • [Int'l Joint Research] Seoul National University/National Institute of Health/National Cancer Center(韓国)

    • Country Name
      KOREA (REP. OF KOREA)
    • Counterpart Institution
      Seoul National University/National Institute of Health/National Cancer Center
    • # of Other Institutions
      6
  • [Int'l Joint Research] Fudan University/Shanghai Jiao Tong University/Sun Yat-sen University(中国)

    • Country Name
      CHINA
    • Counterpart Institution
      Fudan University/Shanghai Jiao Tong University/Sun Yat-sen University
    • # of Other Institutions
      13
  • [Int'l Joint Research]

    • # of Other Countries
      18
  • [Journal Article] Serum soluble Fas levels and incidence of liver cancer in nested case-control study.2023

    • Author(s)
      Adachi Y, Nojima M, Mori M, Kubo T, Akutsu N, Sasaki Y, Nakase H, Lin Y, Kurozawa Y, Wakai K, Tamakoshi A.
    • Journal Title

      Cancer Epidemiol Biomarkers Prev.

      Volume: 32 Pages: 260-265

    • DOI

      10.1158/1055-9965.EPI-22-0902

    • Peer Reviewed
  • [Journal Article] An autopsy case of progressive supranuclear palsy treated with monoclonal antibody against tau.2023

    • Author(s)
      Beck G, Yamashita R, Kido K, Ikenaka K, Chiba T, Yonenobu Y, Saito Y, Morii E, Hasegawa M, Murayama S, Mochizuki H
    • Journal Title

      Neuropathology.

      Volume: - Pages: -

    • DOI

      10.1111/neup.12890

    • Peer Reviewed
  • [Journal Article] Anticancer effect of a pyrrole-imidazole polyamide-triphenylphosphonium conjugate selectively targeting a common mitochondrial DNA cancer risk variant in cervical cancer cells.2023

    • Author(s)
      Yao J, Takenaga K, Koshikawa N, Kida Y, Lin J, Watanabe T, Maru Y, Hippo Y, Yamamoto S, Zhu Y, Nagase H.
    • Journal Title

      Int J Cancer

      Volume: 152 Pages: 962-976

    • DOI

      10.1002/ijc.34319

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Association between Dietary Patterns and Serum Low Density Lipoprotein Cholesterol in Japanese Women and Men: The Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.2023

    • Author(s)
      Kitaoka K, Miura K, Takashima N, Kadota A, Harada A, Nakamura Y, Kita Y, ..., Kuriki K, et al.
    • Journal Title

      J Atheroscler Thromb.

      Volume: - Pages: -

    • DOI

      10.5551/jat.63675

    • Peer Reviewed / Open Access
  • [Journal Article] Association between glycemic traits and primary open-angle glaucoma: A Mendelian randomization study in the Japanese population.2023

    • Author(s)
      Hanyuda A, Goto A, Wakai K,Momozawa Y, Tanno K, Shimizu A, Hozawa A, Kinoshita K, Matsuo K, Yamamoto M, Sasaki M, Tsugane S, Iwasaki M et al
    • Journal Title

      Am J Ophthalmol

      Volume: 245 Pages: 193-201

    • DOI

      10.1016/j.ajo.2022.09.004

    • Peer Reviewed / Open Access
  • [Journal Article] Association of 25-hydroxyvitamin D with risk of overall and colorectal cancer among Japanese using a Mendelian randomization approach.2023

    • Author(s)
      Katagiri R, Goto A, Nakano S, Nakatochi M, Koyanagi YN, Iwagami M, Hanyuda A, ..., Kuriki K, et al.
    • Journal Title

      Sci Rep.

      Volume: 13(1) Pages: 2384

    • DOI

      10.1038/s41598-023-29596-8

    • Peer Reviewed / Open Access
  • [Journal Article] BMI and cardiometabolic traits in Japanese: a Mendelian randomization study.2023

    • Author(s)
      Nagayoshi M, Hishida A, Shimizu T, Kato Y, Kubo Y, Okada R, Tamura T, Otonari J, ..., Kuriki K, et al.
    • Journal Title

      J Epidemiol.

      Volume: - Pages: -

    • DOI

      10.2188/jea.JE20220154

    • Peer Reviewed / Open Access
  • [Journal Article] Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex2023

    • Author(s)
      Yamaguchi K, Yamaguchi R, Sheridan P, Takane K, Ikenoue T, Nagatoishi S, Kozuka-Hata H, Oyama M, Shida D, Tsumoto K, Miyano S, Imoto S, Furukawa Y, et al
    • Journal Title

      iScience

      Volume: - Pages: -

    • DOI

      10.1016/j.isci.2023.106563

    • Peer Reviewed / Open Access
  • [Journal Article] Coffee and Green Tea Consumption and Cardiovascular Disease Mortality Among People With and Without Hypertension2023

    • Author(s)
      Teramoto M, Yamagishi K, Muraki I, Tamakoshi A, Iso H
    • Journal Title

      Journal of the American Heart Journal

      Volume: 12 Pages: e026477

    • DOI

      10.1161/JAHA.122.026477

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Coffee and metabolic phenotypes: A cross-sectional analysis of the Japan multi-institutional collaborative cohort (J-MICC) study.2023

    • Author(s)
      Watanabe T, Arisawa K, Nguyen TV, Ishizu M, Katsuura-Kamano S, Hishida A, Tamura T, ..., Kuriki K, et al.
    • Journal Title

      Nutr Metab Cardiovasc Dis.

      Volume: 33(3) Pages: 620-630

    • DOI

      10.1016/j.numecd.2022.12.019

    • Peer Reviewed / Open Access
  • [Journal Article] Correlations between cerebrospinal fluid homovanillic acid and dopamine transporter SPECT in degenerative parkinsonian syndromes.2023

    • Author(s)
      Goto R, Kurihara M, Kameyama M, Komatsu H, Higashino M, Hatano K, Ihara R, Higashihara M, Nishina Y, Matsubara T, Kanemaru K, Saito Y, Murayama S, Iwata A.
    • Journal Title

      J Neural Transm(Vienna)

      Volume: 130(4) Pages: 513-520

    • DOI

      10.1007/s00702-023-02611-y

    • Peer Reviewed
  • [Journal Article] CSF P-Tau181 and Other Biomarkers in Patients With Neuronal Intranuclear Inclusion Disease.2023

    • Author(s)
      Kurihara M, Komatsu H, Sengoku R, Shibukawa M, Morimoto S, Matsubara T, Arakawa A, Orita M, (12名 省略)Saito Y, Murayama S, Kanemaru K, Iwata A.
    • Journal Title

      Neurology

      Volume: 100(10) Pages: e1009-e1019

    • DOI

      10.1212/WNL.0000000000201647

    • Peer Reviewed
  • [Journal Article] Diagnostic utility of trefoil factor families for the early detection of lung cancer and their correlation with tissue expression2023

    • Author(s)
      Kentaro Minegishi, Yoh Dobashi, Teruhide Koyama, Yuko Ishibashi, Miki Furuya, Hiroyoshi Tsubochi, Yasukazu Ohmoto, Sachiyo Nomura
    • Journal Title

      Oncology Letters

      Volume: 25(4) Pages: 139

    • DOI

      10.3892/ol.2023.13725

    • Peer Reviewed / Open Access
  • [Journal Article] Effects of gene-lifestyle interactions on obesity based on a multi-locus risk score: A cross-sectional analysis.2023

    • Author(s)
      Nakamura S, Fang X, Saito Y, Narimatsu H, Ota A, Ikezaki H, Shimanoe C, ..., Kuriki K, et al.
    • Journal Title

      PLoS One.

      Volume: 18(2) Pages: e0279169

    • DOI

      10.1371/journal.pone.0279169

    • Peer Reviewed / Open Access
  • [Journal Article] Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer2023

    • Author(s)
      Y. Usui, Y. Taniyama, M. Endo, Y. N. Koyanagi, Y. Kasugai, C. Terao, M. Hatakeyama, M. Hirata, T. Yoshida, Y. Murakami, A. B. Spurdle, K. Matsuo and Y. Momozawa
    • Journal Title

      N Engl J Med

      Volume: 13 Pages: 1181-1190

    • DOI

      10.1056/NEJMoa2211807

    • Peer Reviewed
  • [Journal Article] Identification of odontogenic ameloblast associated as a novel target gene of the Wnt/β-catenin signaling pathway.2023

    • Author(s)
      Yamaguchi K, Horie C, Takane K, Ikenoue T, Nakagawa S, Isobe Y, Ushiku T, Tanaka M, Fujishiro J, Hoshino N, Nishizuka S, Aikou S, Shida D, Furukawa Y, et al
    • Journal Title

      Cancer Science

      Volume: 114(3) Pages: 948-960

    • DOI

      10.1111/cas.15657

    • Peer Reviewed
  • [Journal Article] Inflammatory cytokines-enriched microenvironment plays key roles for the development of breast cancers2023

    • Author(s)
      Yasuto Takeuchi, Noriko Gotoh
    • Journal Title

      Cancer Science

      Volume: - Pages: -

    • DOI

      10.1111/cas.15734

    • Peer Reviewed / Open Access
  • [Journal Article] LATE-NC staging in routine neuropathologic diagnosis: an update.2023

    • Author(s)
      Nelson PT, Lee EB, Cykowski MD, .... , Saito Y(50人中37番目), ..... , Neumann M
    • Journal Title

      Acta Neuropathol.

      Volume: 145 Pages: 159-173

    • DOI

      10.1007/s00401-022-02524-2

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] LOXL1 and LOXL4 are novel target genes of the Zn2+-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells2023

    • Author(s)
      Hirabayashi D, Yamamoto KI, Maruyama, A Toyooka S, Inoue Y, Sakaguchi M
    • Journal Title

      Frontiers in Oncology

      Volume: 13 Pages: 1142886

    • DOI

      10.3389/fonc.2023.1142886

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Moderate-to-vigorous Physical Activity and Sedentary Behavior Are Independently Associated With Renal Function: A Cross-sectional Study2023

    • Author(s)
      Megumi Hara, Yuichiro Nishida, Keitaro Tanaka, Chisato Shimanoe, Kayoko Koga, Takuma Furukawa, Yasuki Higaki, Koichi Shinchi, Hiroaki Ikezaki,et al
    • Journal Title

      Journal of Epidemiology

      Volume: - Pages: -

    • DOI

      10.2188/jea.JE20210155

    • Peer Reviewed / Open Access
  • [Journal Article] Neuropathology of spinocerebellar ataxia type 8: Common features and unique tauopathy.2023

    • Author(s)
      Yonenobu Y, Beck G, Kido K, Maeda N, Yamashita R, Inoue K, Saito Y, Hasegawa M, Ito H, Hasegawa K, Morii E, Iwaki T, Murayama S, Mochizuki H.
    • Journal Title

      Neuropathology

      Volume: - Pages: -

    • DOI

      10.1111/neup.12894

    • Peer Reviewed
  • [Journal Article] Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells2023

    • Author(s)
      Gohara Y, Tomonobu N, Kinoshita R, Watanabe M, Kumon H, Sakaguchi M
    • Journal Title

      Journal of molecular medicine (Berlin, Germany)

      Volume: - Pages: -

    • DOI

      10.1007/s00109-023-02292-w

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] PPARα activation partially drives NAFLD development in liver-specific Hnf4a-null mice2023

    • Author(s)
      Kasano-Camones CI, Takizawa M, Ohshima N, Sakaguchi M, Gonzalez FJ, Inoue Y
    • Journal Title

      The Journal of Biochemistry

      Volume: - Pages: -

    • DOI

      10.1093/jb/mvad005

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Proteolytic cleavage of membrane proteins by membrane type-1 MMP regulates cancer malignant progression.2023

    • Author(s)
      Ikeda K, Kaneko R, Tsukamoto E, Funahashi N, Koshikawa N.
    • Journal Title

      Cancer Sci.

      Volume: 114(2) Pages: 348-356

    • DOI

      10.1111/cas.15638

    • Peer Reviewed / Open Access
  • [Journal Article] Proteomic profile of nuclei containing p62-positive inclusions in a patient with neuronal intranuclear inclusion disease2023

    • Author(s)
      Kurihara M, Mano T, Eto F, Yao I, Ishiura H, Ikemura M, Matsubara T, Morishima M, Saito Y, Murayama S, Toda T, Setou M, Iwata A
    • Journal Title

      Neurobiology of Disease

      Volume: 177 Pages: 105989

    • DOI

      10.1016/j.nbd.2023.105989

    • Peer Reviewed / Open Access
  • [Journal Article] SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells2023

    • Author(s)
      Gao T, Yang X, Fujisawa M, Sakaguchi M, Yoshimura T, Matsukawa A
    • Journal Title

      International journal of molecular sciences

      Volume: 24 Pages: 4996

    • DOI

      10.3390/ijms24054996

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The association between sleep parameters and sarcopenia in Japanese community-dwelling older adults2023

    • Author(s)
      Takuma Shibuki, Miho Iida, Sei Harada, Toru Takebayashi, et al.
    • Journal Title

      Archives of Gerontology and Geriatrics

      Volume: 109 Pages: 104948

    • DOI

      10.1016/j.archger.2023.104948

    • Peer Reviewed / Open Access
  • [Journal Article] 18F-THK5351 PET for visualizing predominant lesions of pathologically confirmed corticobasal degeneration presenting with frontal behavioral-spatial syndrome2022

    • Author(s)
      Yuji Saitoh, Etsuko Imabayashi, Masashi Mizutani, Tadashi Tsukamoto, Masato Hasegawa, Yuko Saito, Hiroshi Matsuda, Yuji Takahashi
    • Journal Title

      J Neurol

      Volume: 269 Pages: 5157-5161

    • DOI

      10.1007/s00415-022-11121-y

    • Peer Reviewed / Open Access
  • [Journal Article] A critical review of "uterine leiomyoma" with subsequent recurrence or metastasis: A multicenter study of 62 cases2022

    • Author(s)
      Sanada S, Ushijima K, Yanai H, Mikami Y, Ohishi Y, Kobayashi H, Tashiro H, Mikami M, Miyamoto S, Katabuchi H
    • Journal Title

      J Obstet Gynaecol Res

      Volume: 48(12) Pages: 3242-3251

    • DOI

      10.1111/jog.15426

    • Peer Reviewed / Open Access
  • [Journal Article] A genome-wide association study on adherence to low-carbohydrate diets in Japanese.2022

    • Author(s)
      Nakamura Y, Tamura T, Narita A, Shimizu A, Sutoh Y, Takashima N, Matsui K, .... Kuirki K, et al.
    • Journal Title

      Eur J Clin Nutr.

      Volume: 76(8) Pages: 1103-1110

    • DOI

      10.1038/s41430-022-01090-w

    • Peer Reviewed
  • [Journal Article] A Histochemical Analysis of Neurofibrillary Tangles in Olfactory Epithelium, a Study Based on an Autopsy Case of Juvenile Alzheimer's Disease.2022

    • Author(s)
      Shimizu S, Tojima I, Nakamura K, Kouzaki H, Kanesaka T, Ogawa N, Hashizume Y, Akatsu H, Hori A, Tooyama I, Shimizu T.
    • Journal Title

      Acta Histochem Cytochem.

      Volume: 55(3) Pages: 93-98

    • DOI

      10.1267/ahc.22-00048

    • Peer Reviewed / Open Access
  • [Journal Article] A meta-analysis of genome-wide association studies using Japanese and Taiwanese has revealed novel loci associated with gout susceptibility.2022

    • Author(s)
      Chang SJ, Wakai K, Matsuo H et al.
    • Journal Title

      Human Cell

      Volume: 35 Pages: 767-770

    • DOI

      10.1007/s13577-021-00665-2

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A postmortem study suggests a revision of the dual-hit hypothesis of Parkinson's disease2022

    • Author(s)
      Borghammer P, Just MK, Horsager J, Raunio A, Kok EH, Savola S, Murayama S, Saito Y, Myllykangas L, Van Den Berge N
    • Journal Title

      NPJ Parkinsons Dis

      Volume: 8 Pages: 166

    • DOI

      10.1038/s41531-022-00436-2

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Actin-binding protein filamin-A drives tau aggregation and contributes to progressive supranuclear palsy pathology.2022

    • Author(s)
      Tsujikawa K, Hamanaka K, Riku Y, 他30名中22番目
    • Journal Title

      Sci Adv.

      Volume: 8 Pages: eabm5029

    • DOI

      10.1126/sciadv.abm5029

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Age-dependent formation of TMEM106B amyloid filaments in human brains.2022

    • Author(s)
      Schweighauser M, Arseni D, Bacioglu M, (10名), Tarutani A, Murayama S, Miyazaki M, Saito Y, 他14名
    • Journal Title

      Nature

      Volume: 605 Pages: 310-314

    • DOI

      10.1038/s41586-022-04650-z

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] An autopsied case report of spastic paraplegia with thin corpus callosum carrying a novel mutation in the SPG11 gene: widespread degeneration with eosinophilic inclusions2022

    • Author(s)
      Mika Hayakawa, Tomoyasu Matsubara, Yoko Mochizuki, Chisen Takeuchi, Motoyuki Minamitani, Masayuki Imai, Kenjiro Kosaki, Tomio Arai, Shigeo Murayama
    • Journal Title

      BMC Neurology

      Volume: 22(1) Pages: 2

    • DOI

      10.1186/s12883-021-02514-z

    • Peer Reviewed / Open Access
  • [Journal Article] An autopsy case of Alzheimer's disease with amygdala-predominant Lewy pathology presenting with frontotemporal dementia-like psychiatric symptoms.2022

    • Author(s)
      Beck G, Shigenobu K, Ukon K, Yamashita R, Yonenobu Y, Morii E, Hasegawa M, Ikeda M, Murayama S, Mochizuki H.
    • Journal Title

      Neuropathology

      Volume: 42 Pages: 147-154

    • DOI

      10.1111/neup.12786

    • Peer Reviewed
  • [Journal Article] An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection.2022

    • Author(s)
      Goto R, Kawakami H, Horiuchi Y, Chikada A, Yasuda T, Suzuki T, Miyazato Y, Ishikane M, Kishino Y, Miyazaki H, Igari T, Katano H, Suzuki T, Murayama S, Arai N.
    • Journal Title

      Intern Med.

      Volume: 61 Pages: 3439-3444

    • DOI

      10.2169/internalmedicine.9726-22

    • Peer Reviewed / Open Access
  • [Journal Article] An Extensive-stage Small-cell Lung Cancer Case With Preexisting Lambert-Eaton Myasthenic Syndrome Successfully Treated With an Immune Checkpoint Inhibitor2022

    • Author(s)
      Tadashi Sakaguchi, Yasumasa Kokubo, Kazuki Furuhashi, Yuki Nakamura, Yuta Suzuki, Kentaro Ito, Kentaro Fujiwara, Yoichi Nishii, Osamu Taguchi, Osamu Hataji
    • Journal Title

      Clin Lung Cancer

      Volume: 23(3) Pages: e273-e275

    • DOI

      10.1016/j.cllc.2021.09.001

    • Peer Reviewed / Open Access
  • [Journal Article] Antenatal corticosteroids and outcomes of small for gestational age infants born at 24-31 gestational weeks: a population-based propensity score matching analysis2022

    • Author(s)
      Takafumi Ushida, Masahiro Nakatochi, Yumiko Kobayashi, Noriyuki Nakamura, Kazuya Fuma, Yukako Iitani, Kenji Imai, Yoshiaki Sato, Masahiro Hayakawa
    • Journal Title

      Archives of Gynecology and Obstetrics

      Volume: - Pages: -

    • DOI

      10.1007/s00404-022-06834-4

    • Peer Reviewed
  • [Journal Article] APOE Alleles With Tau and Aβ Pathology in Patients With Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex in the Kii Peninsula2022

    • Author(s)
      Ryogen Sasaki, Satoru Morimoto, Fumiko Ozawa, Hideyuki Okano, Mari Yoshida, Hiroyuki Ishiura, Shoji Tsuji, Shigeki Kuzuhara, and Yasumasa Kokubo
    • Journal Title

      Neurology

      Volume: 99 Pages: e2437-e2442

    • DOI

      10.1212/WNL.0000000000201156

    • Peer Reviewed / Open Access
  • [Journal Article] Association Between Cerebral Microbleeds and Circulating Levels of Mid-Regional Pro-Adrenomedullin2022

    • Author(s)
      Kuriyama N, Koyama T, et al.
    • Journal Title

      J Alzheimers Dis.

      Volume: 88 Pages: 731-741

    • DOI

      10.3233/JAD-220195

    • Peer Reviewed / Open Access
  • [Journal Article] Association between daily sleep duration and the risk of incident dementia according to the presence or absence of diseases among older Japanese individuals in the New Integrated Suburban Seniority Investigation (NISSIN) project.2022

    • Author(s)
      Shigekazu Ukawa, Wenjing Zhao, Satoe Okabayashi, Takashi Kimura, Masahiko Ando, Kenji Wakai, Kazuyo Tsushita, Takashi Kawamura, Akiko Tamakoshi.
    • Journal Title

      Sleep medicine.

      Volume: 100 Pages: 190-195

    • DOI

      10.1016/j.sleep.2022.08.022

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Association between germline pathogenic variants and breast cancer risk in Japanese women: the HERPACC study2022

    • Author(s)
      Kasugai Y, Kohmoto T, Taniyama Y, Koyanagi YN, Usui Y, Iwase M, Oze I, Yamaguchi R, Ito H, Imoto I, Matsuo K.
    • Journal Title

      Cancer Sci

      Volume: 113(4) Pages: 1451-1462

    • DOI

      10.1111/cas.15312

    • Peer Reviewed / Open Access
  • [Journal Article] Association between Sedentary Time and Falls among Middle-Aged Women in Japan.2022

    • Author(s)
      Ozaki E, Matsui D, Kuriyama N, Tomida S, Nukaya Y, Koyama T.
    • Journal Title

      Healthcare

      Volume: 10 Pages: 2354

    • DOI

      10.3390/healthcare10122354

    • Peer Reviewed / Open Access
  • [Journal Article] Association between Serum Magnesium Levels and Mortality in a Community-Based Population: The Yamagata (Takahata) Study2022

    • Author(s)
      Ashitomi Y, Konta T, Motoi F, Watanabe M, Kayama T, Ueno Y.
    • Journal Title

      J Nutr Sci Vitaminol (Tokyo)

      Volume: 68 Pages: 270-275

    • DOI

      10.3177/jnsv.68.270

    • Peer Reviewed / Open Access
  • [Journal Article] Association between stress coping strategy and functional disability in the general older adult population: the Takashima study.2022

    • Author(s)
      Naoyuki Takashima, Yasuyuki Nakamura, Naoko Miyagawa, Aya Kadota, Sachiko Tanaka-Mizuno, Kenji Matsui, Katsuyuki Miura, Hirotsugu Ueshima, Yoshikuni Kita
    • Journal Title

      Gerontology

      Volume: 68(6) Pages: 699-706

    • DOI

      10.1159/000519194

    • Peer Reviewed / Open Access
  • [Journal Article] Association of dietary diversity with all-cause mortality by body mass index in Japanese older adults: An age-specific prospective cohort study (NISSIN project).2022

    • Author(s)
      Saeka Takabayashi, Takumi Hirata, Wenjing Zhao, Takashi Kimura, Shigekazu Ukawa, Kazuyo Tsushita, Kenji Wakai, Takashi Kawamura, Masahiko Ando, Akiko Tamakoshi
    • Journal Title

      Geriatrics & gerontology international.

      Volume: 22(9) Pages: 736-744

    • DOI

      10.1111/ggi.14446

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Association of Low-Density Lipoprotein Cholesterol with Risk of Coronary Heart Disease and Stroke among Middle-Aged Japanese Workers: An Analysis using Inverse Probability Weighting.2022

    • Author(s)
      Al-Shoaibi AAA, Li Y, Song Z, Chiang C, Hirakawa Y, Saif-Ur-Rahman KM, Shimoda M, Nakano Y, Matsunaga M, Aoyama A, Tamakoshi K, Ota A, Yatsuya H.
    • Journal Title

      J Atheroscler Thromb.

      Volume: - Pages: -

    • DOI

      10.5551/jat.63519

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Association of perceived stress and coping strategies with the renal function in middle-aged and older Japanese men and women.2022

    • Author(s)
      Koga K, Hara M, Shimanoe C, Nishida Y, Furukawa T, Iwasaka C, Tanaka K, ..., Kuriki K, et al.
    • Journal Title

      Sci Rep.

      Volume: 12(1) Pages: 291

    • DOI

      10.1038/s41598-021-04324-2

    • Peer Reviewed / Open Access
  • [Journal Article] Association of skipping breakfast and short sleep duration with the prevalence of metabolic syndrome in the general Japanese population: Baseline data from the Japan Multi-Institutional Collaborative cohort study.2022

    • Author(s)
      Katsuura-Kamano S, Arisawa K, Uemura H, Van Nguyen T, Takezaki T, Ibusuki R, Suzuki S, ..., Kuriki K, et al.
    • Journal Title

      Prev Med Rep.

      Volume: 24 Pages: 101613

    • DOI

      10.1016/j.pmedr.2021.101613

    • Peer Reviewed / Open Access
  • [Journal Article] Associations of breastfeeding history with metabolic syndrome and cardiovascular risk factors in community-dwelling parous women: The Japan Multi-Institutional Collaborative Cohort Study.2022

    • Author(s)
      Matsunaga T, Kadomatsu Y, Tsukamoto M, Kubo Y, Okada R, Nagayoshi M, Tamura T, ... Kuriki K, et al.
    • Journal Title

      PLoS One.

      Volume: 17(1) Pages: e0262252

    • DOI

      10.1371/journal.pone.0262252

    • Peer Reviewed / Open Access
  • [Journal Article] Associations of Genome-Wide Polygenic Risk Score and Risk Factors With Hypertension in a Japanese Population.2022

    • Author(s)
      Fujii R, Hishida A, Nakatochi M, et al.
    • Journal Title

      Circ Genom Precis Med.

      Volume: 15 Pages: e003612

    • DOI

      10.1161/CIRCGEN.121.003612

    • Peer Reviewed
  • [Journal Article] Associations of metabolic syndrome and metabolically unhealthy obesity with cancer mortality: The Japan Multi-Institutional Collaborative Cohort (J-MICC) study.2022

    • Author(s)
      Nguyen TV, Arisawa K, Katsuura-Kamano S, Ishizu M, Nagayoshi M, Okada R, Hishida A, ..., et al.
    • Journal Title

      PLoS One.

      Volume: 17(7) Pages: e0269550.

    • DOI

      10.1371/journal.pone.0269550

    • Peer Reviewed / Open Access
  • [Journal Article] Associations with oral health indices for obesity risk among Japanese men and women: results from the baseline data of a cohort study.2022

    • Author(s)
      Tanaka H, Nakano M, Kuriki K; Shizuoka-Sakuragaoka J-MICC Study Group.
    • Journal Title

      BMC Public Health.

      Volume: 22(1) Pages: 1595

    • DOI

      10.1186/s12889-022-13998-w

    • Peer Reviewed / Open Access
  • [Journal Article] Autopsy Validation of the Diagnostic Accuracy of 123 I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease2022

    • Author(s)
      Tomoyasu Matsubara,Masashi Kameyama,Noriko Tanaka,Renpei Sengoku,Makoto Orita,Ko Furuta,Atsushi Iwata,Tomio Arai,Hirofumi Maruyama,Yuko Saito,Shigeo Murayama
    • Journal Title

      Neurology

      Volume: 98(16) Pages: e1648-e1659

    • DOI

      10.1212/WNL.0000000000200110

    • Peer Reviewed / Open Access
  • [Journal Article] Biological insights into systemic lupus erythematosus through an immune cell-specific transcriptome-wide association study.2022

    • Author(s)
      Yin X, Kim K, Suetsugu H, Bang SY, Wen L, Okada Y, Matsuda K, Matsuo K, Kochi Y, Zhang X, Terao C, Cui Y, Bae SC.
    • Journal Title

      Ann Rheum Dis

      Volume: 81 Pages: 1273-80

    • DOI

      10.1136/annrheumdis-2022-222345

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Blood lipids and the risk of colorectal cancer: Mendelian randomization analyses in the Japanese Consortium of Genetic Epidemiology studies2022

    • Author(s)
      M. Iwagami, A. Goto, A. Shimizu, A. Hozawa, K. Kinoshita, I. Oze, K. Kuriki, S. Suzuki, I. Imoto, Y. Momozawa, K. Matsuo, S. Tsugane, K. Wakai M. Iwasaki.
    • Journal Title

      Cancer Prev Res

      Volume: 15(12) Pages: 827-836

    • DOI

      10.1158/1940-6207.CAPR-22-0146

    • Peer Reviewed / Open Access
  • [Journal Article] CA-125 Levels Are Predictive of Survival in Low-Grade Serous Ovarian Cancer-A Multicenter Analysis.2022

    • Author(s)
      Wohlmuth C, Djedovic V, Kjaer SK, Matsuo K, Karlan BY, Lester J, Goodman MT, Thompson PJ, Pejovic T, Riggan MJ, Lajkosz K, Tone A, May T.
    • Journal Title

      Cancers

      Volume: 14 Pages: 1954

    • DOI

      10.3390/cancers14081954

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Changes in behavioral activities and transition of depressive symptoms among younger-old community-dwelling adults during 6 years: An age-specific prospective cohort study.2022

    • Author(s)
      Yifan Shan, Wenjing Zhao, Wen Hao, Takashi Kimura, Shigekazu Ukawa, Hideki Ohira, Takashi Kawamura, Kenji Wakai, Masahiko Ando, Akiko Tamakoshi.
    • Journal Title

      International journal of geriatric psychiatry.

      Volume: 37(8) Pages: -

    • DOI

      10.1002/gps.5778

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Changes in social activities and the occurrence and persistence of depressive symptoms: Do type and combination of social activities make a difference?2022

    • Author(s)
      Yifan Shan, Wenjing Zhao, Wen Hao, Takashi Kimura, Shigekazu Ukawa, Hideki Ohira, Takashi Kawamura, Kenji Wakai, Masahiko Ando, Akiko Tamakoshi.
    • Journal Title

      Archives of gerontology and geriatrics.

      Volume: 104 Pages: 104800

    • DOI

      10.1016/j.archger.2022.104800

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Characterization of Opa interacting protein 5 as a new biomarker and therapeutic target for oral cancer2022

    • Author(s)
      Ming Zhu, Atsushi Takano, Bayarbat Tsevegjav, Yoshihiro Yoshitake, Masanori Shinohara, Yataro Daigo
    • Journal Title

      International journal of oncology

      Volume: 60(3) Pages: 27

    • DOI

      10.3892/ijo.2022.5317

    • Peer Reviewed
  • [Journal Article] Checking the validity and reliability of the Japanese version of the Mini-Cog using a smartphone application2022

    • Author(s)
      Saito Y, Nakamura S, Tanaka A, Watanabe R, Narimatsu H, Chung UI
    • Journal Title

      BMC Research Notes

      Volume: 15 Pages: 222

    • DOI

      10.1186/s13104-022-06101-4

    • Peer Reviewed / Open Access
  • [Journal Article] Chronological Change in EPHA2 Protein Expression Is Associated With Recurrence of Bladder Cancer.2022

    • Author(s)
      Koizumi M, Sato S, Yoshihara M, Nakamura Y, Terao H, Okubo Y, Washimi K,Yoshioka E, Yokose T, Kishida T, Koshikawa N, Miyagi Y.
    • Journal Title

      Anticancer Res.

      Volume: 42(12) Pages: 5783-5794

    • DOI

      10.21873/anticanres.16085

    • Peer Reviewed
  • [Journal Article] Circulating immune- and inflammation-related biomarkers and early-stage noncardia gastric cancer risk.2022

    • Author(s)
      Song M, Rabkin CS, Ito H, Oze I, Koyanagi YN, Pfeiffer RM, Kasugai Y, Matsuo K, Camargo MC.
    • Journal Title

      Eur J Cancer Prev

      Volume: 31 Pages: 270-273

    • DOI

      10.1097/CEJ.0000000000000706

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Claudins and Gastric Cancer: An Overview.2022

    • Author(s)
      Hashimoto I, Oshima T
    • Journal Title

      Cancers

      Volume: 14(2) Pages: 290

    • DOI

      10.3390/cancers14020290

    • Peer Reviewed / Open Access
  • [Journal Article] Clinical evaluation of urine laminin-γ2 monomer as a potent biomarker for non-muscle invasive bladder cancer.2022

    • Author(s)
      Karashima T, Umemoto S, Kishida T, Osaka K, Nakagawa M, Yoshida E, Yoshimura T, Sakaguchi M, Nishimoto H, Tai M, Inoue K, Seiki M, Koshikawa N, Shuin T.
    • Journal Title

      Cancer Med.

      Volume: 12(3) Pages: 2453-2462

    • DOI

      10.1002/cam4.5087

    • Peer Reviewed / Open Access
  • [Journal Article] Coffee Consumption Reduces Gout Risk Independently of Serum Uric Acid Levels: Mendelian Randomization Analyses Across Ancestry Populations2022

    • Author(s)
      Shirai Y, Nakayama A, Kawamura Y, Toyoda Y, Nakatochi M, Shimizu S, Shinomiya N, Okada Y, Matsuo H, Japan Gout.
    • Journal Title

      ACR Open Rheumatol.

      Volume: 4 Pages: 534-539

    • DOI

      10.1002/acr2.11425

    • Peer Reviewed / Open Access
  • [Journal Article] Contribution of copy number variations to the risk of severe eating disorders2022

    • Author(s)
      Kushima I, Imaeda M, Tanaka S, Kato H, Oya-Ito T, Nakatochi M, Aleksic B, Ozaki N.
    • Journal Title

      Psychiatry Clin Neurosci

      Volume: 76 Pages: 423-428

    • DOI

      10.1111/pcn.13430

    • Peer Reviewed / Open Access
  • [Journal Article] Correction to: Risk assessment in the patients with uterine cervical cancer harboring intermediate risk factors after radical hysterectomy: a multicenter, retrospective analysis by the Japanese Gynecologic Oncology Group.2022

    • Author(s)
      Shigeta S, Shimada M, Tsuji K, Nagai T, Tanase Y, Matsuo K, Kamiura S, Iwata T, Yokota H, Mikami M.
    • Journal Title

      Int J Clin Oncol

      Volume: 27(9) Pages: 1516

    • DOI

      10.1007/s10147-022-02211-y

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Correction to: Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43.2022

    • Author(s)
      Tarutani A, Adachi T, Akatsu H, Hashizume Y, Hasegawa K, Saito Y, Robinson AC, Mann DMA, Yoshida M, Murayama S, Hasegawa M.
    • Journal Title

      Acta Neuropathol.

      Volume: 144 Pages: 165

    • DOI

      10.1007/s00401-022-02439-y

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] COVID-19-related stigma and its relationship with mental wellbeing: A cross-sectional analysis of a cohort study in Japan2022

    • Author(s)
      Emiko Sawaguchi, Sho Nakamura, Kaname Watanabe, Kanami Tsuno, Hiromi Ikegami, Naoko Shinmura, Yoshinobu Saito, Hiroto Narimatsu
    • Journal Title

      Fronties in Public Health

      Volume: - Pages: 1010720

    • DOI

      10.3389/fpubh.2022.1010720

    • Peer Reviewed / Open Access
  • [Journal Article] Cross-Disorder Analysis of Genic and Regulatory Copy Number Variations in Bipolar Disorder, Schizophrenia, and Autism Spectrum Disorder2022

    • Author(s)
      Kushima I, Nakatochi M, Aleksic B, Okada T, Kimura H, Kato H, Morikawa M, Inada T, Ishizuka K, Torii Y, Ozaki N.
    • Journal Title

      Biol Psychiatry.

      Volume: 92 Pages: 362-374

    • DOI

      10.1016/j.biopsych.2022.04.003

    • Peer Reviewed / Open Access
  • [Journal Article] Current status of hereditary breast and ovarian cancer practice among gynecologic oncologists in Japan: a nationwide survey by the Japan Society of Gynecologic Oncology (JSGO)2022

    • Author(s)
      Kobayashi Y, Masuda K, Mikami M, et al; Working Group on Clinical Practice for Cancer Genomic Medicine and HBOC, Japan Society of Gynecologic Oncology.
    • Journal Title

      J Gynecol Oncol

      Volume: 33(5) Pages: e61

    • DOI

      10.3802/jgo.2022.33.e61

    • Peer Reviewed / Open Access
  • [Journal Article] De novo transgenerational inheritance of male rat hyperactivity by rotenone2022

    • Author(s)
      Masami Ishido
    • Journal Title

      Fund Toxicol Sci

      Volume: 9 Pages: 111-115

    • DOI

      10.2131/fts.9.111

    • Open Access
  • [Journal Article] Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.2022

    • Author(s)
      Fernandez-Rozadilla C, Timofeeva M, Matsuo K, Houlston R, Peters R.
    • Journal Title

      Nat Genet

      Volume: 55 Pages: 89-99

    • DOI

      10.1038/s41588-022-01222-9

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Developing and validating polygenic risk scores for colorectal cancer risk prediction in East Asians.2022

    • Author(s)
      Ping J, Yang Y, Wen W, Kweon SS, Matsuda K, Jia WH, Shin A, Gao YT, Matsuo K, Kim J, Zheng W.
    • Journal Title

      Int J Cancer

      Volume: 151 Pages: 1726-1736

    • DOI

      10.1002/ijc.34194

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Dietary Patterns Derived from Reduced Rank Regression Are Associated with the 5-Year Occurrence of Metabolic Syndrome: Aichi Workers' Cohort Study.2022

    • Author(s)
      Li Y, Yatsuya H, Wang C, Uemura M, Matsunaga M, He Y, Khine M, Ota A.
    • Journal Title

      Nutrients

      Volume: 14 Pages: 3019

    • DOI

      10.3390/nu14153019

    • Peer Reviewed / Open Access
  • [Journal Article] Dkk3/REIC deficiency impairs spermiation, sperm fibrous sheath integrity and the sperm motility of mice2022

    • Author(s)
      Xue R, Lin W, Fujita H, Sun J, Kinoshita R, Ochiai K, Futami J, Watanabe M, Ohuchi H, Sakaguchi M, Tang Z, Huang P, Nasu Y, Kumon H
    • Journal Title

      Genes

      Volume: 13 Pages: 285

    • DOI

      10.3390/genes13020285

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] DNA methylation level of the gene encoding thioredoxin-interacting protein in peripheral blood cells is associated with metabolic syndrome in the Japanese general population2022

    • Author(s)
      Yamazaki M, Yamada H, Munetsuna E, Maeda K, Ando Y, Mizuno G, Fujii R, Tsuboi Y, Ohashi K, Ishikawa H, Hashimoto S, Hamajima N, Suzuki K.
    • Journal Title

      Endocrine Journal

      Volume: 69(3) Pages: 319-326

    • DOI

      10.1507/endocrj.EJ21-0339

    • Peer Reviewed / Open Access
  • [Journal Article] Effect of Ankle Weights as a Frailty Prevention Strategy in the Community-Dwelling Elderly: A Preliminary Report2022

    • Author(s)
      Akatsu H, Manabe T, Kawade Y, Masaki Y, Hoshino S, Jo T, Kobayashi S, Hayakawa T, Ohara H.
    • Journal Title

      Int J Environ Res Public Health

      Volume: 19(12) Pages: 7350

    • DOI

      10.3390/ijerph19127350

    • Peer Reviewed / Open Access
  • [Journal Article] Effect of the interaction between physical activity and estimated macronutrient intake on HbA1c: population-based cross-sectional and longitudinal studies.2022

    • Author(s)
      Furukawa T, Nishida Y, Hara M, Shimanoe C, Koga K, Iwasaka C, Higaki Y, ..., Kuriki K, et al.
    • Journal Title

      BMJ Open Diabetes Res Care.

      Volume: 10(1) Pages: e002479

    • DOI

      10.1136/bmjdrc-2021-002479

    • Peer Reviewed / Open Access
  • [Journal Article] Enhancement of LTD-like plasticity by associative pairing of quadripulse magnetic stimulation with peripheral nerve stimulation.2022

    • Author(s)
      Wiratman W, Murakami T, Tiksnadi A, Kobayashi S, Hanajima R, Ugawa Y.
    • Journal Title

      Clin Neurophysiol

      Volume: 138 Pages: 9-17.

    • DOI

      10.1016/j.clinph.2022.03.009

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Epigenome-Wide Association Study Identified VTI1A DNA Methylation Associated With Accelerometer-Assessed Physical Activity.2022

    • Author(s)
      Nishida Y, Hara M, Ohmomo H, Ono K, Shimizu A, Horita M, Shimanoe C, Taguchi N, Higaki Y, Tanaka K
    • Journal Title

      Med Sci Sports Exerc.

      Volume: 54 Pages: 1879-1888

    • DOI

      10.1249/MSS.0000000000002970

    • Peer Reviewed
  • [Journal Article] Evaluation of the validity and reliability of the 10-meter walk test using a smartphone application among Japanese older adults2022

    • Author(s)
      Saito Y, Nakamura S, Tanaka A, Watanabe R, Narimatsu H, Chung UI.
    • Journal Title

      Front Sports Act Living

      Volume: 4 Pages: 904924

    • DOI

      10.3389/fspor.2022.904924

    • Peer Reviewed / Open Access
  • [Journal Article] Excessive folic acid intake combined with undernutrition during gestation alters offspring behavior and brain monoamine profiles2022

    • Author(s)
      Ono T., Hino K., Kimura T., Uchimura Y., Ashihara T., Higa T., Kojima H., Murakami T., Udagawa J.
    • Journal Title

      Congenital Anomalies

      Volume: 62 Pages: 169-180

    • DOI

      10.1111/cga.12472

    • Peer Reviewed
  • [Journal Article] Exosomal Wnt7a from a low metastatic subclone promotes lung metastasis of a highly metastatic subclone in the murine 4t1 breast cancer2022

    • Author(s)
      Li C, Yoshimura T, Tian M, Wang Y, Kondo T, Yamamoto KI, Fujisawa M, Ohara T, Sakaguchi M, Matsukawa A
    • Journal Title

      Breast cancer research

      Volume: 24 Pages: 60

    • DOI

      10.1186/s13058-022-01557-5

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Experimental design of a stable isotope labeling derivatized UHPLC-MS/MS method for the detection/quantification of primary/secondary bile acids in biofluids2022

    • Author(s)
      Muguruma Y, Nagatomo R, Kamatsuki S, Miyabe K, Asano G, Akatsu H, Inoue K.
    • Journal Title

      J Pharm Biomed Anal.

      Volume: 209 Pages: 114485

    • DOI

      10.1016/j.jpba.2021.114485

    • Peer Reviewed
  • [Journal Article] Expression of Transferrin Protein and Messenger RNA in Neural Cells from Mouse and Human Brain Tissue2022

    • Author(s)
      Abe E, Fuwa TJ, Hoshi K, Saito T, Murakami T, Miyajima M, Ogawa N, Akatsu H, Hashizume Y, Hashimoto Y, Honda T
    • Journal Title

      Metabolites

      Volume: 12(7) Pages: 594

    • DOI

      10.3390/metabo12070594

    • Peer Reviewed / Open Access
  • [Journal Article] Functional Blockage of S100A8/A9 Ameliorates Ischemia-Reperfusion Injury in the Lung2022

    • Author(s)
      Nakata K, Okazaki M, Sakaue T, Kinoshita R, Komoda Y, Shimizu D, Yamamoto H, Tanaka S, Suzawa K, Shien K, Miyoshi K, Yamamoto H, ..., Sakaguchi M, Toyooka S
    • Journal Title

      Bioengineering

      Volume: 9 Pages: 673

    • DOI

      10.3390/bioengineering9110673

    • Peer Reviewed / Open Access
  • [Journal Article] Genetic polymorphism of pleiotrophin is associated with pain experience in Japanese adults: Case-control study.2022

    • Author(s)
      Saita K, Sumitani M, Nishizawa D, Tamura T, Ikeda K, Wakai K, Sudo Y, ..., Kuriki K, et al.
    • Journal Title

      Medicine (Baltimore).

      Volume: 101(37) Pages: e30580.

    • DOI

      10.1097/MD.0000000000030580

    • Peer Reviewed / Open Access
  • [Journal Article] Genome- and transcriptome-wide association studies of 386,000 Asian and European-ancestry women provide new insights into breast cancer genetics.2022

    • Author(s)
      Jia G, Ping J, Shu X, Yang Y, Cai Q, Matsuda K, Matsuo K, Kang D, Easton DF, Simard J, Shu XO, Long J, Zheng W.
    • Journal Title

      Am J Hum Genet

      Volume: 109 Pages: 2185-2195

    • DOI

      10.1016/j.ajhg.2022.10.011

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Genome-wide meta-analysis between renal overload type and renal underexcretion type of clinically defined gout in Japanese populations2022

    • Author(s)
      Toyoda Y, Nakayama A, Nakatochi M, Kawamura Y, Nakaoka H, Yamamoto K, ..., Ichida K, Inoue I, Shinomiya N, Matsuo H, Japan Gout.
    • Journal Title

      Mol Genet Metab

      Volume: 136 Pages: 186-189

    • DOI

      10.1016/j.ymgme.2022.01.100

    • Peer Reviewed / Open Access
  • [Journal Article] High Prevalence of HTLV-1 Carriers Among the Elderly Population in Kagoshima, a Highly Endemic Area in Japan2022

    • Author(s)
      Yuichi Tashiro, Eiji Matsuura, Yasuko Sagara, Satoshi Nozuma, Daisuke Kodama, Masakazu Tanaka, Chihaya Koriyama, Ryuji Kubota, Hiroshi Takashima
    • Journal Title

      AIDS Res Hum Retroviruses

      Volume: 38(5) Pages: 363-369

    • DOI

      10.1089/AID.2021.0164

    • Peer Reviewed
  • [Journal Article] Histidine-rich glycoprotein suppresses the S100A8/A9-mediated organ-tropic metastasis of melanoma cells2022

    • Author(s)
      Tomonobu N, Kinoshita R, Wake H, Inoue Y, Murata H, Yamamoto K-I, Futami J, Yamauchi A, Kuribayashi F, Kondo E, Toyooka S, Nishibori M, Sakaguchi M
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Pages: 10300

    • DOI

      10.3390/ijms231810300

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Holliday junction recognition protein as a prognostic biomarker and therapeutic target for oral cancer2022

    • Author(s)
      Bayarbat Tsevegjav, Atsushi Takano , Ming Zhu, Yoshihiro Yoshitake, Masanori Shinohara, Yataro Daigo
    • Journal Title

      International journal of oncology

      Volume: 60(3) Pages: 26

    • DOI

      10.3892/ijo.2022.5316

    • Peer Reviewed
  • [Journal Article] Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusions.2022

    • Author(s)
      Park H, Yamanaka T, Toyama Y, Fujita A, Doi H, Nirasawa T, Murayama S, Matsumoto N, Shimogori T, Ikegawa M, Haltia MJ, Nukina N.
    • Journal Title

      Acta Neuropathol Commun.

      Volume: 10(1) Pages: 28

    • DOI

      10.1186/s40478-022-01333-8

    • Peer Reviewed / Open Access
  • [Journal Article] Impact of adjuvant chemotherapy on the overall survival of patients with resectable bulky small cell neuroendocrine cervical cancer: a JSGO-JSOG joint study.2022

    • Author(s)
      Seino M, Nagase S, Ohta T, Yamagami W, Ebina Y, Kobayashi Y, Tabata T, Kaneuchi M, Enomoto T, Mikami M.
    • Journal Title

      J Gynecol Oncol

      Volume: 34(1) Pages: e4

    • DOI

      10.3802/jgo.2023.34.e4

    • Peer Reviewed / Open Access
  • [Journal Article] Impact of modifiable healthy lifestyle adoption on lifetime gain from middle to older age2022

    • Author(s)
      Ryoto Sakaniwa, Midori Noguchi, Hironori Imano , Kokoro Shirai, Akiko Tamakoshi, Hiroyasu Iso; JACC Study Group
    • Journal Title

      Age Ageing.

      Volume: 51(5) Pages: afac080

    • DOI

      10.1093/ageing/afac080

    • Peer Reviewed / Open Access
  • [Journal Article] Impact of socioeconomic status and sibling number on the prevalence of Helicobacter pylori infection: a cross-sectional study in a Japanese population.2022

    • Author(s)
      Elshair M, Ugai T, Oze I, Kasugai Y, Koyanagi YN, Hara K, Ito H, Matsuo K.
    • Journal Title

      Nagoya J Med Sci

      Volume: 84 Pages: 374-387

    • DOI

      10.18999/nagjms.84.2.374

    • Peer Reviewed / Open Access
  • [Journal Article] Incorporating progesterone receptor expression into the PREDICT breast prognostic model.2022

    • Author(s)
      Grootes I, Keeman R, Blows FM, Lambrechts D, Li J, Manoochehri M, Margolin S, Matsuo K, Pharoah PDP.
    • Journal Title

      Eur J Cancer

      Volume: 173 Pages: 178-193

    • DOI

      10.1016/j.ejca.2022.06.011

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Increasing frequency of gene copy number aberrations is associated with immunosuppression and predicts poor prognosis in gastric adenocarcinoma.2022

    • Author(s)
      Arnaldo N S Silva, Yuichi Saito, Takaki Yoshikawa, Takashi Oshima, William Allum, Matthew G Nankivell, Gordon Hutchins, David Cunningham, Heike I Grabsch.
    • Journal Title

      The British journal of surgery

      Volume: 109(3) Pages: 291-297

    • DOI

      10.1093/bjs/znab460

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Increasing horizontal transmission of human T-cell leukemia virus type 1 in adolescents and young adults in Japan2022

    • Author(s)
      Yasuko Sagara, Hitomi Nakamura, Masahiro Satake, Toshiki Watanabe, Isao Hamaguchi
    • Journal Title

      J Clin Virol

      Volume: 157 Pages: 105324

    • DOI

      10.1016/j.jcv.2022.105324

    • Peer Reviewed / Open Access
  • [Journal Article] Inhibiting S100A8/A9 attenuates airway obstruction in a mouse model of heterotopic tracheal transplantation2022

    • Author(s)
      Shimizu D, Okazaki M, Sugimoto S, Kinoshita R, Nakata K, Tanaka S, Hashimoto K, Miyoshi K, Yamane M, Matsukawa A, Sakaguchi M, Toyooka S
    • Journal Title

      Biochemical and biophysical research communications

      Volume: 629 Pages: 86-94

    • DOI

      10.1016/j.bbrc.2022.08.087

    • Peer Reviewed / Open Access
  • [Journal Article] Inhibition of pancreatic cancer-cell growth and metastasis in vivo by a pyrazole compound characterized as a cell-migration inhibitor by an in vitro chemotaxis assay2022

    • Author(s)
      Okamoto S, Miyano K, Choshi T, Sugisawa N, Nishiyama T, Kotouge R, Yamamura M, Sakaguchi M, Kinoshita R, Tomonobu N, Katase N, ..., Yamauchi A, Kuribayashi
    • Journal Title

      Biomedicine & pharmacotherapy

      Volume: 155 Pages: 113733-113733

    • DOI

      10.1016/j.biopha.2022.113733

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Interictal epileptiform discharges as a predictive biomarker for recurrence of poststroke epilepsy.2022

    • Author(s)
      Abe S, Tanaka T, Fukuma K, Matsubara S, Motoyama R, Mizobuchi M, Yoshimura H, (10名) Murayama S, Matsumoto R, Takahashi R, Ikeda A, Ihara M
    • Journal Title

      Brain Commun.

      Volume: 4 Pages: fcac312

    • DOI

      10.1093/braincomms/fcac312

    • Peer Reviewed / Open Access
  • [Journal Article] Investigation of miRNA expression profiles using cohort samples reveals potential early detectability of colorectal cancers by serum miR-26a-5p before clinical diagnosis2022

    • Author(s)
      Hishida A, Yamada H, Ando Y, Okugawa Y, Shiozawa M, Miyagi Y, Daigo Y, Toiyama Y, Shirai Y, Tanaka K, Takeuchi K, Wakai K, et al.
    • Journal Title

      Oncology Letters

      Volume: 23(3) Pages: 87

    • DOI

      10.3892/ol.2022.13207

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Irregular sleep and all-cause mortality: A large prospective cohort study.2022

    • Author(s)
      Omichi C, Koyama T, Kadotani H, Ozaki E, Tomida S, Yoshida , Otonari J, ..., Kuriki K, et al.
    • Journal Title

      Sleep Health.

      Volume: 8(6) Pages: 678-683

    • DOI

      10.1016/j.sleh.2022.08.010

    • Peer Reviewed / Open Access
  • [Journal Article] Large-scale Integrated Analysis of Genetics and Metabolomic Data Reveals Potential Links Between Lipids and Colorectal Cancer Risk.2022

    • Author(s)
      Shu X, Chen Z, Long J, Guo X, Yang Y, Kamatani Y, Kim DH, Kim J, Kweon SS, Le Marchand L, Matsuda K, Matsuo K, Peters U, Zheng W.
    • Journal Title

      Cancer Epidemiol Biomarkers Prev

      Volume: 31 Pages: 1216-1226

    • DOI

      10.1158/1055-9965.EPI-21-1008

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE12022

    • Author(s)
      Komaki K, Takano T, Sato Y, Asada A, Ikeda S, Yamada K, ...., Murayama S, ...., Fukuda M, Hisanaga SI.
    • Journal Title

      J Biochem

      Volume: 170 Pages: 729-738

    • DOI

      10.1093/jb/mvab094

    • Peer Reviewed
  • [Journal Article] Lewy Body Disease Primate Model with α-Synuclein Propagation from the Olfactory Bulb.2022

    • Author(s)
      Sawamura M, Onoe H, Tsukada H, Isa K, Yamakado H, Okuda S, Ikuno M, Hatanaka Y, Murayama S, Uemura N, Isa T, Takahashi R.
    • Journal Title

      Mov Disord.

      Volume: 37 Pages: 2033-2044

    • DOI

      10.1002/mds.29161

    • Peer Reviewed
  • [Journal Article] Lifestyle and personal factors associated with having macroscopic residual disease after ovarian cancer primary cytoreductive surgery.2022

    • Author(s)
      Phung MT, Webb PM, DeFazio A, Fasching PA, Goode EL, Goodman MT, Karlan BY, Lester J, Matsuo K, Berchuck A, Ramus SJ, Pearce CL
    • Journal Title

      Gynecol Oncol

      Volume: 168 Pages: 68-75

    • DOI

      10.1016/j.ygyno.2022.10.018

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Long-term variability and change trend of systolic blood pressure and risk of type 2 diabetes mellitus in middle-aged Japanese individuals: findings of the Aichi Workers' Cohort Study.2022

    • Author(s)
      Song Z, He Y, Chiang C, Al-Shoaibi AAA, Saif-Ur-Rahman KM, Mamun MR, Aoyama A, Hirakawa Y, Matsunaga M, Ota A, Tamakoshi K, Li Y, Yatsuya H.
    • Journal Title

      Hypertens Res.

      Volume: 45(11) Pages: 1772-1780

    • DOI

      10.1038/s41440-022-00993-2

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Mitochondrial complex I abnormalities underlie neurodegeneration and cognitive decline in Alzheimer's disease2022

    • Author(s)
      Terada T, Therriault J, Kang MS, Savard M, Pascoal TA, Bezgin G, Matsudaira T, Bunai T, Obi T, Tsukada H, Ouchi Y, Rosa-Neto P
    • Journal Title

      Eur J Neurol.

      Volume: 29(5) Pages: 1324-1334

    • DOI

      10.1111/ene.15246

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Modulations of bioactive lipids and their receptors in postmortem Alzheimer's disease brains.2022

    • Author(s)
      Kurano M, Saito Y, Uranbileg B, Saigusa D, Kano K, Aoki J, Yatomi Y.
    • Journal Title

      Front Aging Neurosci

      Volume: 14 Pages: 1066578

    • DOI

      10.3389/fnagi.2022.1066578

    • Peer Reviewed / Open Access
  • [Journal Article] Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration.2022

    • Author(s)
      Riku Y, Iwasaki Y, Ishigaki S, Akagi A, Hasegawa M, Nishioka K, Li Y, Riku M, Ikeuchi T, Fujioka Y, .. Yoshida M, Katsuno M, Sobue G.
    • Journal Title

      Brain

      Volume: 145 Pages: 2769-2784.

    • DOI

      10.1093/brain/awac091

    • Peer Reviewed / Open Access
  • [Journal Article] Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.2022

    • Author(s)
      Ishigaki K, Sakaue S, Terao C, Matsuo K, Louis Bridges S Jr, Padyukov L, Martin J, Klareskog L, Okada Y, Raychaudhuri S.
    • Journal Title

      Nat Genet

      Volume: 54 Pages: 1640-1651

    • DOI

      10.1038/s41588-022-01213-w

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] New insights into the genetic contribution of ALDH2 rs671 in pancreatic carcinogenesis: Evaluation by mediation analysis2022

    • Author(s)
      Koyanagi YN, Oze I, Kasugai Y, Kawakatsu Y, Taniyama Y, Hara K, Shimizu Y, Imoto I, Ito H, Matsuo K.
    • Journal Title

      Cancer Sci

      Volume: 113(4) Pages: 1441-1450

    • DOI

      10.1111/cas.15286

    • Peer Reviewed / Open Access
  • [Journal Article] Nuclear pore destruction and loss of nuclear TDP-43 in FUS mutation-related amyotrophic lateral sclerosis motor neurons2022

    • Author(s)
      Aizawa H, Teramoto S, Hideyama T, Kato H, Terashi H, Suzuki Y, Kimura T, Kwak S
    • Journal Title

      J Neurol Sci

      Volume: 436 Pages: 120187

    • DOI

      10.1016/j.jns.2022.120187

    • Peer Reviewed
  • [Journal Article] OAT10/SLC22A13 Acts as a Renal Urate Re-Absorber: Clinico-Genetic and Functional Analyses With Pharmacological Impacts2022

    • Author(s)
      Toyoda Y, Kawamura Y, Nakayama A, Morimoto K, ..., Tamura T, Kondo T, Kato Y, Ichida K, Suzuki H, Shinomiya N, Kobayashi Y, Takada T, Matsuo H.
    • Journal Title

      Front Pharmacol.

      Volume: 13 Pages: 842717

    • DOI

      10.3389/fphar.2022.842717

    • Peer Reviewed / Open Access
  • [Journal Article] Paclitaxel-carboplatin and bevacizumab combination with maintenance bevacizumab therapy for metastatic, recurrent, and persistent uterine cervical cancer: An open-label multicenter phase II trial (JGOG1079).2022

    • Author(s)
      Tanigawa T, Takeshima N, Ishikawa H, Nishio S, Usami T, Yamawaki T, Oishi T, Ihira K, Kato H, Goto M, Saito M, Taira Y, Yokoyama M, Mikami M, et al.
    • Journal Title

      Gynecol Oncol

      Volume: 165(3) Pages: 413-419

    • DOI

      10.1016/j.ygyno.2022.04.011

    • Peer Reviewed / Open Access
  • [Journal Article] Pathology-associated change in levels and localization of SIDT2 in postmortem brains of Parkinson's disease and dementia with Lewy bodies patients2022

    • Author(s)
      Fujiwara Y, Kabuta C, Sano T, Murayama S, Saito Y, Kabuta T.
    • Journal Title

      Neurochem Int

      Volume: 152 Pages: 105243

    • DOI

      10.1016/j.neuint.2021.105243

    • Peer Reviewed
  • [Journal Article] Phosphorylated alpha-synuclein in Iba1-positive macrophages in the skin of patients with Parkinson's disease2022

    • Author(s)
      Oizumi H, Yamasaki K, Suzuki H, Ohshiro S, Saito Y, Murayama S, Sugimura Y, Hasegawa T, Fukunaga K, Takeda A .
    • Journal Title

      Ann Clin Transl Neurol.

      Volume: 9 Pages: 1136-1146.

    • DOI

      10.1002/acn3.51610

    • Peer Reviewed / Open Access
  • [Journal Article] Phosphorylation of hTERT at threonine 249 is a novel tumor biomarker of aggressive cancer with poor prognosis in multiple organs.2022

    • Author(s)
      Matsuda Y, Daigo Y, Miyagi Y, Yokose T, Oshima T, Ito H, Morinaga S, Kishida T, Minamoto T, et al.
    • Journal Title

      the Journal of Pathology

      Volume: 257(2) Pages: 172-185

    • DOI

      10.1002/path.5876

    • Peer Reviewed / Open Access
  • [Journal Article] Physical activity and risk of mortality from heart failure among Japanese population2022

    • Author(s)
      Kushima T, Yamagishi K, Kihara T, Tamakoshi A, Iso H
    • Journal Title

      J Atheroscler Thromb

      Volume: 29(7) Pages: 1076-1084

    • DOI

      10.5551/jat.62843

    • Peer Reviewed / Open Access
  • [Journal Article] piRNA/PIWI Protein Complex as a Potential Biomarker in Sporadic Amyotrophic Lateral Sclerosis.2022

    • Author(s)
      Abdelhamid RF, Ogawa K, Beck G, Ikenaka K, Takeuchi E, Yasumizu Y, Jinno J, Kimura Y, Baba K, Nagai Y, Okada Y, Saito Y, Murayama S, Mochizuki H, Nagano S.
    • Journal Title

      Molecular Neurobiology

      Volume: 59 Pages: 1693-1705

    • DOI

      10.1007/s12035-021-02686-2

    • Peer Reviewed
  • [Journal Article] Plasma mid-regional pro-adrenomedullin: A biomarker of the ischemic penumbra in hyperacute stroke.2022

    • Author(s)
      Ishiyama H, Tanaka T, Saito S, Koyama T, Kitamura A, Inoue M, Fukushima N, Morita Y, Koga M, Toyoda K, Kuriyama N, Urushitani M, Ihara M.
    • Journal Title

      Brain Pathol.

      Volume: 33(2) Pages: e13110

    • DOI

      10.1111/bpa.13110

    • Peer Reviewed / Open Access
  • [Journal Article] Plasma miR-151-3p as a Candidate Diagnostic Biomarker for Head and Neck Cancer: A Cross-sectional Study within the INHANCE Consortium.2022

    • Author(s)
      Pastorino R, Sassano M, Danilo Boffetta P, Matsuo K, Oze I, Brennan P, Boccia S.
    • Journal Title

      Cancer Epidemiol Biomarkers Prev

      Volume: 31 Pages: 2237-2243

    • DOI

      10.1158/1055-9965.EPI-22-0376

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Plasmalogen in the brain: Effects on cognitive functions and behaviors attributable to its properties.2022

    • Author(s)
      Udagawa J., Hino K.
    • Journal Title

      Brain Research Bulletin

      Volume: 188 Pages: 197-202

    • DOI

      10.1016/j.brainresbull.2022.08.008

    • Peer Reviewed
  • [Journal Article] Positive psychological factors and the risk of pneumonia-associated mortality: Japan Collaborative Cohort Study.2022

    • Author(s)
      Sumiyama A, Shirai K, Imano H, Eguchi E, Muraki I, Tamakoshi A, Iso H; for JACC Study Group
    • Journal Title

      J Psychosom Res.

      Volume: 160 Pages: 110971

    • DOI

      10.1016/j.jpsychores.2022.110971

    • Peer Reviewed / Open Access
  • [Journal Article] Potential role of HTLV-1 Tax-specific cytotoxic t lymphocytes expressing a unique t-cell receptor to promote inflammation of the central nervous system in myelopathy associated with HTLV-12022

    • Author(s)
      Tanaka Y, Sato T, Yagishita N, Yamauchi J, Araya N, Aratani S, Takahashi K, Kunitomo Y, Nagasaka M, Kanda Y, Uchimaru K, Morio T, Yamano Y.
    • Journal Title

      Frontiers in Immunology

      Volume: 13 Pages: 993025

    • DOI

      10.3389/fimmu.2022.993025

    • Peer Reviewed / Open Access
  • [Journal Article] Prognostic factors of 2018 FIGO stage IB-IIA cervical cancer with absence of high/ intermediate surgical-pathological risk factors.2022

    • Author(s)
      Shibuya Y, Shimada M, Tsuji K, Shigeta S, Tanase Y, Matsuo K, Yamaguchi S, Kanao H, Saito T, Mikami M
    • Journal Title

      Jpn J Clin Oncol

      Volume: 52(11) Pages: 1289-1296

    • DOI

      10.1093/jjco/hyac125

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prolyl isomerase Pin1 expression in the spinal motor neuron of sporadic amyotrophic lateral sclerosis2022

    • Author(s)
      88.Kato H, Naito M, Saito T, Hideyama T, Suzuki Y, Kimura T, Kwak S, Aizawa H
    • Journal Title

      J Clin Neurol

      Volume: 18 Pages: 463-469

    • DOI

      10.3988/jcn.2022.18.4.46

    • Peer Reviewed
  • [Journal Article] Proteolytic ectodomain shedding of muscle-specific tyrosine kinase in myasthenia gravis.2022

    • Author(s)
      Mori S, Suzuki S, Konishi T, (11名) Murayama S, Shigemoto K.
    • Journal Title

      Exp Neurol.

      Volume: 361 Pages: 114300

    • DOI

      10.1016/j.expneurol.2022.114300

    • Peer Reviewed / Open Access
  • [Journal Article] Purpose in life ( Ikigai) and employment status in relation to cardiovascular mortality: the Japan Collaborative Cohort Study2022

    • Author(s)
      Junji Miyazaki, Kokoro Shirai, Takashi Kimura, Satoyo Ikehara, Akiko Tamakoshi, Hiroyasu Iso
    • Journal Title

      BMJ Open.

      Volume: 12(10) Pages: e059725

    • DOI

      10.1136/bmjopen-2021-059725

    • Peer Reviewed / Open Access
  • [Journal Article] RAISING is a high-performance method for identifying random transgene integration sites.2022

    • Author(s)
      Wada Y, Sato T, Hasegawa H, Matsudaira T, Nao N, Watanabe T, Yamano Y, Saito M, et al.
    • Journal Title

      Communication Biology

      Volume: 5(1) Pages: 535

    • DOI

      10.1038/s42003-022-03467-w

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Recombination of repeat elements generates somatic complexity in human genomes.2022

    • Author(s)
      Pascarella G, Hon CC, Hashimoto K, (9名) Murayama S, Suzuki Y, Gustincich S, Frith M, Carninci P
    • Journal Title

      Cell

      Volume: 185 Pages: 3025-3040

    • DOI

      10.1016/j.cell.2022.06.032

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP-induced neurotoxicity2022

    • Author(s)
      Cao Q, Zou Q, Zhao X, Zhang Y, Qu Y, Wang N, Murayama S, Qi Q, Hashimoto K, Lin S, Zhang JC
    • Journal Title

      Cell Death Discov

      Volume: 8 Pages: 267

    • DOI

      10.1038/s41420-022-01063-9

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Relevance of the MHC region for breast cancer susceptibility in Asians.2022

    • Author(s)
      Ho PJ, Khng AJ, Tan BK, Tan EY, Tan SM, Matsuo K, Mohd-Taib NA, Muir K, Murphy RA, Park SK, Shen CY, Shu XO, Easton DF, Pharoah PDP, Hartman M, Li J.
    • Journal Title

      Breast Cancer

      Volume: 29 Pages: 869-879

    • DOI

      10.1007/s12282-022-01366-w

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Risk assessment in the patients with uterine cervical cancer harboring intermediate risk factors after radical hysterectomy: a multicenter, retrospective analysis by the Japanese Gynecologic Oncology Group.2022

    • Author(s)
      Shigeta S, Shimada N,Tsuji K, Nagai T, Tanase Y, Matsuo K, Kamiura S, Iwata T, Yokota H, Mikami M
    • Journal Title

      Int J Clin Oncol

      Volume: 27(9) Pages: 1507-1515

    • DOI

      10.1007/s10147-022-02198-6

    • Peer Reviewed / Open Access
  • [Journal Article] Sedentary time, physical activity, and serum SPARC in a middle-aged population2022

    • Author(s)
      Nishida Y, Hara M, Higaki Y, Taguchi N, Nakamura K, Nanri H, Imaizumi T, Sakamoto T, Shimanoe C, Horita M, Shinchi K, Tanaka K
    • Journal Title

      European Journal of Sport Science

      Volume: 22 Pages: 1786-1794

    • DOI

      10.1080/17461391.2021.1974573

    • Peer Reviewed
  • [Journal Article] Sentinel node navigation surgery in cervical cancer: a systematic review and metaanalysis.2022

    • Author(s)
      Chiyoda T, Yoshihara K, Kagabu M, Nagase S, Katabuchi H, Mikami M, Tabata T, Hirashima Y, Kobayashi Y, Kaneuchi M, Tokunaga H, Baba T
    • Journal Title

      Int J Clin Oncol

      Volume: 27(8) Pages: 1247-1255

    • DOI

      10.1007/s10147-022-02178-w

    • Peer Reviewed / Open Access
  • [Journal Article] Sex- and age-specific all-cause mortality in insomnia with hypnotics: Findings from Japan multi-institutional Collaborative Cohort Study.2022

    • Author(s)
      Sogawa R, Shimanoe C, Tanaka K, Hara M, Nishida Y, Furukawa T, Nagayoshi M, ..., Kuriki K, et al.
    • Journal Title

      Sleep Med.

      Volume: 100 Pages: 410-418.

    • DOI

      10.1016/j.sleep.2022.09.020

    • Peer Reviewed / Open Access
  • [Journal Article] Sleep Duration and Daytime Napping and Risk of Type 2 Diabetes among Japanese Men and Women: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk2022

    • Author(s)
      Reiko Okada, Masayuki Teramoto, Isao Muraki, Akiko Tamakoshi, Hiroyasu Iso
    • Journal Title

      Journal of Epidemiology

      Volume: - Pages: -

    • DOI

      10.2188/jea.JE20220118

    • Peer Reviewed / Open Access
  • [Journal Article] SNP-based heritability estimates of gout and its subtypes determined by genome-wide association studies of clinically defined gout2022

    • Author(s)
      Toyoda Y, Nakatochi M, Nakayama A, Kawamura Y, Nakaoka H, Wakai K, Matsuo K, Matsuo H, Japan Gout.
    • Journal Title

      Rheumatology (Oxford).

      Volume: 17 Pages: keac597

    • DOI

      10.1093/rheumatology/keac597

    • Peer Reviewed / Open Access
  • [Journal Article] Soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for differential diagnosis of mild cognitive impairment.2022

    • Author(s)
      Araki W, Kanemaru K, Hattori K, Tsukamoto T, Saito Y, 他11名
    • Journal Title

      Aging Clin Exp Res.

      Volume: 34 Pages: 341-347

    • DOI

      10.1007/s40520-021-01935-7

    • Peer Reviewed
  • [Journal Article] Structures of tau and α-synuclein filaments from brains of patients with neurodegenerative diseases.2022

    • Author(s)
      Kametani F, Hasegawa M.
    • Journal Title

      Neurochem Int.

      Volume: 158 Pages: 105362

    • DOI

      10.1016/j.neuint.2022.105362

    • Peer Reviewed
  • [Journal Article] Structures of α-synuclein filaments from human brains with Lewy pathology.2022

    • Author(s)
      Yang Y, Shi Y, Schweighauser M, (5名 省略)Saito Y, (4名 省略) Murayama S, Revesz T, Ghetti B, Hasegawa M, Lashley T, Scheres SHW, Goedert M
    • Journal Title

      Nature.

      Volume: 610 Pages: 791-795

    • DOI

      10.1038/s41586-022-05319-3

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Subjective irregular sleep is associated with metabolic syndrome: A cross-sectional study.2022

    • Author(s)
      Ogura Y, Koyama T, Ozaki E, Omichi C, Uehara R.
    • Journal Title

      Prev Med Rep.

      Volume: 28 Pages: 101844

    • DOI

      10.1016/j.pmedr.2022.101844

    • Peer Reviewed / Open Access
  • [Journal Article] Super-additive associations between parity and education level on mortality from cardiovascular disease and other causes: the Japan Collaborative Cohort Study.2022

    • Author(s)
      Yasukawa S, Eguchi E, Tamakoshi A, Iso H; for JACC Study Group.
    • Journal Title

      BMC Womens Health

      Volume: 22(1) Pages: 278

    • DOI

      10.1186/s12905-022-01805-y

    • Peer Reviewed / Open Access
  • [Journal Article] Suppression of abnormal α-synuclein expression by activation of BDNF transcription ameliorates Parkinson's disease-like pathology2022

    • Author(s)
      Cao Q, Luo S, Yao W, Qu Y, Wang N, Hong J, Murayama S, Zhang Z, Chen J, Hashimoto K, Qi Q, Zhang JC.
    • Journal Title

      Mol Ther Nuclear Acids

      Volume: 29 Pages: 1-15.

    • DOI

      10.1016/j.omtn.2022.05.037

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Suppression of non-small-cell lung cancer A549 tumor growth by an mtDNA mutation-targeting pyrrole-imidazole polyamide-triphenylphosphonium and a senolytic drug.2022

    • Author(s)
      Tsuji K, Kida Y, Koshikawa N, Yamamoto S, Shinozaki Y, Watanabe T, Lin J, Nagase H, Takenaga K.
    • Journal Title

      Cancer Sci.

      Volume: 113 Pages: 1321-1337

    • DOI

      10.1111/cas.15290

    • Peer Reviewed / Open Access
  • [Journal Article] TDP-43 Proteinopathy Presenting with Typical Symptoms of Parkinson's Disease.2022

    • Author(s)
      Yamashita R, Beck G, Yonenobu Y, Inoue K, Mitsutake A, Ishiura H, Hasegawa M, Murayama S, Mochizuki H.
    • Journal Title

      Mov Disord.

      Volume: 37 Pages: 1561-1563

    • DOI

      10.1002/mds.29048

    • Peer Reviewed
  • [Journal Article] Testing of the therapeutic efficacy and safety of AMPA receptor RNA aptamers in a sporadic ALS mouse model2022

    • Author(s)
      87.Akamatsu M, Yamashita T, Teramoto S, Huang Z, Lynch J, Toda T, Niu L, Kwak S
    • Journal Title

      Life Science Alliance

      Volume: 5 Pages: e202101193

    • DOI

      10.26508/lsa.202101193

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Association Between Living Area in Childhood and Respiratory Disease Mortality in Adulthood2022

    • Author(s)
      Ayumu Iwasaki, Masayuki Teramoto, Isao Muraki, Kokoro Shirai, Akiko Tamakoshi, Hiroyasu Iso
    • Journal Title

      Int J Public Health

      Volume: 67 Pages: 1604778

    • DOI

      10.3389/ijph.2022.1604778

    • Peer Reviewed / Open Access
  • [Journal Article] The association of reproductive history with hypertension and obesity according to menopausal status: the J-MICC Study2022

    • Author(s)
      M. Ohashi, K. Miura, N. Takashima, K. Tanaka, T. Takezaki, S. Suzuki, K. Kuriki, K. Arisawa, H. Ikezaki, I. Oze, H. Mikami, K. Takeuchi, Y. Kita, K. Wakai
    • Journal Title

      Hypertens Res

      Volume: 45(4) Pages: 708-714

    • DOI

      10.1038/s41440-021-00820-0

    • Peer Reviewed
  • [Journal Article] The association of smoking cessation with mortality from pneumonia among middle-aged and elderly community residents: The Japan Collaborative Cohort (JACC) study2022

    • Author(s)
      Kihara T, Yamagishi K, Iso H, Tamakoshi A
    • Journal Title

      Prev Med

      Volume: 163 Pages: 107188

    • DOI

      10.1016/j.ypmed.2022.107188

    • Peer Reviewed
  • [Journal Article] The cAMP/PKA/CREB and TGF-β/SMAD4 pathways regulate stemness and metastatic potential in colorectal cancer cells2022

    • Author(s)
      Teruaki Fujishita, Yasushi Kojima, Rie Kajino-Sakamoto, Emi Mishiro-Sato, Yasuhiro Shimizu, Waki Hosoda, Rui Yamaguchi, Makoto Mark Taketo, Masahiro Aoki
    • Journal Title

      Cancer Research

      Volume: 82 Pages: 4179-4190

    • DOI

      10.1158/0008-5472.CAN-22-1369

    • Peer Reviewed
  • [Journal Article] The inhibitory effects of anti-ERC/Mesothelin antibody 22A31 on colorectal adenocarcinoma cells, within a mouse xenograft model.2022

    • Author(s)
      Taniguchi G, Kajino K, Momose S, Saeki H, Yue L, Ohtsuji N, Abe M, Shibuya T, Orimo A, Nagahara A, Watanabe S, Hino O.
    • Journal Title

      Cancers

      Volume: 14(9) Pages: 2198

    • DOI

      10.3390/cancers14092198

    • Peer Reviewed / Open Access
  • [Journal Article] The oncogenic driving force of CD30 signaling-induced chromosomal instability in adult T-cell leukemia/lymphoma2022

    • Author(s)
      Makoto Nakashima, Atae Utsunomiya, Toshiki Watanabe, Ryouichi Horie, Kaoru Uchimaru
    • Journal Title

      Cancer Science

      Volume: 114(4) Pages: 1556-1568

    • DOI

      10.1111/cas.15706

    • Peer Reviewed / Open Access
  • [Journal Article] Thymidine Kinase 2 and Mitochondrial Protein COX I in the Cerebellum of Patients with Spinocerebellar Ataxia Type 31 Caused by Penta-nucleotide Repeats (TTCCA)n.2022

    • Author(s)
      Aoki H, Higashi M, Okita M, Ando N, Murayama S, Ishikawa K, Yokota T.
    • Journal Title

      Cerebellum.

      Volume: 22(1) Pages: 70-84

    • DOI

      10.1007/s12311-021-01364-2

    • Peer Reviewed
  • [Journal Article] Toll-like receptor 4 promotes bladder cancer progression upon S100A8/A9 binding, which requires TIRAP-mediated TPL2 activation2022

    • Author(s)
      Rodrigo AGH, Tomonobu N, Kinoshita R, Murata H, Yamamoto K-I, Futami J, Yamauchi A, Kuribayashi F, Inoue Y, Kondo E, Toyooka S, Nishibori M, Sakaguchi M
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 634 Pages: 83-91

    • DOI

      10.1016/j.bbrc.2022.09.116

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43.2022

    • Author(s)
      Tarutani A, Adachi T, Akatsu H, Hashizume Y, Hasegawa K, Saito Y, Robinson AC, Mann DMA, Yoshida M, Murayama S, Hasegawa M
    • Journal Title

      Acta Neuropathol.

      Volume: 143 Pages: 613-640

    • DOI

      10.1007/s00401-022-02426-3

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Unique Lewy pathology in myotonic dystrophy type 1.2022

    • Author(s)
      Sano T, Kawazoe T, Shioya A, Mori-Yoshimura M, Oya Y, Maruo K, Nishino I, Hoshino M, Murayama S, Saito Y.
    • Journal Title

      Neuropathology

      Volume: 42(2) Pages: 104-116

    • DOI

      10.1111/neup.12790

    • Peer Reviewed
  • [Journal Article] Weak shoulder and arm sparing signs in amyotrophic lateral sclerosis.2022

    • Author(s)
      Hamada Y, Kanbayashi T, Takahashi K, Kamiya H, Kobayashi S, Sonoo M.
    • Journal Title

      Muscle Nerve

      Volume: 65(3) Pages: 311-316

    • DOI

      10.1002/mus.27480

    • Peer Reviewed
  • [Journal Article] クライオ電顕が解き明かす神経変性疾患のメカニズム2022

    • Author(s)
      長谷川成人
    • Journal Title

      医学のあゆみ+D5:G6

      Volume: 283(13) Pages: 1109-1137

  • [Journal Article] 加齢, 変性疾患とDNA損傷修復不全2022

    • Author(s)
      岡澤 均
    • Journal Title

      老年精神医学雑誌

      Volume: 33(6) Pages: 603-617

  • [Journal Article] 胎生期環境と精神神経発達2022

    • Author(s)
      宇田川 潤
    • Journal Title

      BIO Clinica

      Volume: 37 Pages: 20-23

  • [Presentation] 20歳から中年期までの体重変化は、中年期から老年期までの体重変化から独立したフレイル発症関連要因である2023

    • Author(s)
      洪 英在、吉田 裕子、Razib Mamun、Zean Song、Yupeng He、李 媛英、松永 眞章、中野 嘉久、江 啓発、平川 仁尚、大塚 礼、太田 充彦、玉腰 浩司、八谷 寛
    • Organizer
      第33回日本疫学会学術総会
  • [Presentation] 2型糖尿病罹患者における代謝関連遺伝子のDNA メチル化解析:愛知職域コホート研究2023

    • Author(s)
      市村 秀俊、李 媛英、山田 宏哉、鈴木 康司、内藤 久雄、太田 充彦、玉腰 浩司、八谷 寛
    • Organizer
      第33回日本疫学会学術総会
  • [Presentation] ADH1B rs1229984は飲酒強度の変化以外の機序でも食道がんリスクを上げる:媒介解析の結果2023

    • Author(s)
      小柳 友理子、杉本 幸弘、川勝 雪乃、尾瀬 功、谷山 祐香里、春日井 由美子、伊藤 秀美、若井 建志、松尾 恵太郎
    • Organizer
      第33回 日本疫学会学術総会
  • [Presentation] Changes in social activities and the occurrence and persistence of depressive symptoms: do type and combination of social activities make a difference?2023

    • Author(s)
      Shan Y, Zhao W, Hao W, Kimura T, Ukawa S, Ohira H, Kawamura T, Wakai K, Ando M, Tamakoshi A.
    • Organizer
      第33回日本疫学会学術総会
  • [Presentation] Mitochondrial dysfunction underlies neurodegeneration in Alzheimer’s disease: A PET study2023

    • Author(s)
      Tatsuhiro TERADA, Joseph Therriault, Takashi Matsudaira, Hirotsugu Takashima, Tomokazu Obi, Hideo Tsukada, Pedro Rosa-Neto, Yasuomi Ouchi
    • Organizer
      19th conference of peace throught MindBrain science
    • Int'l Joint Research
  • [Presentation] Non-restorative Sleep and Diabetes incidence: the Aichi Workers' Cohort Study2023

    • Author(s)
      Lin J, Song Z, Hirakawa Y, Chiang C, Nakano Y, Li Y, Matsunaga M, Ota A, Tamakoshi K, Yatsuya H.
    • Organizer
      第33回日本疫学会学術総会
  • [Presentation] Predictive Value Of Long-term Systolic Blood Pressure Variability For The Development Of Type 2 Diabetes Mellitus2023

    • Author(s)
      Yatsuya H, Song Z, Hong YJ, Mamun MR, Yoshida Y, Akter T, Nuamah G, Tajima R, Lin J, Al-shoaibi A, Chiang C, Nakano Y, Li Y, Matsunaga M, Ota A, Tamakoshi K.
    • Organizer
      EPI | Lifestyle 2023 Scientific Sessions
    • Int'l Joint Research
  • [Presentation] Small Dense Low-Density Lipoprotein Cholesterol - a Strong Atherogenic Lipoprotein2023

    • Author(s)
      池崎裕昭、古庄憲浩、村田昌之、下野信行、林 純、Schaefer EJ
    • Organizer
      第87回日本循環器学会学術集会
    • Invited
  • [Presentation] Variants of Neurocan, a nonalcoholic fatty liver disease risk allele, are associated with plaque development in the carotid artery over 5 years2023

    • Author(s)
      Ikezaki H, Schaefer EJ, Murata M, Shimono N
    • Organizer
      EPI/Lifestyle 2023
    • Int'l Joint Research
  • [Presentation] パーキンソン病の前頭葉機能障害は脳萎縮と相関する2023

    • Author(s)
      寺田達弘、宮田淳、久保田学、吉住美穂、小尾智一、村井俊哉
    • Organizer
      第25回日本ヒト脳機能マッピング学会
  • [Presentation] 四季における腸内細菌叢を介した糖代謝指標に対する緑茶摂取量の関連2023

    • Author(s)
      伊東葵、橘拓希、川島晃子、川畑春佳、後藤千穂、栗木清典
    • Organizer
      第33回日本疫学会学術総会
  • [Presentation] 森林散策頻度と疲労度との関連:J-MICC Study 静岡地区2023

    • Author(s)
      森田えみ、川合紗世、内藤真理子、若井建志
    • Organizer
      第134回日本森林学会大会
  • [Presentation] 神経変性疾患に蓄積する異常タンパク質の生化学、構造解析2023

    • Author(s)
      長谷川成人
    • Organizer
      第22回国際ナノテクノロジー総合展・技術会議
    • Invited
  • [Presentation] 睡眠薬の服用を伴う不眠症の性・年齢特異的な死亡リスク:J-MICC Study 2004-20142023

    • Author(s)
      島ノ江千里、祖川倫太郎、原めぐみ、西田裕一郎、古川拓馬、田中恵太郎
    • Organizer
      第33回日本疫学会
  • [Presentation] 生活習慣を通じた死亡の社会格差: JMICCデータを用いた分析(中間報告)2023

    • Author(s)
      財津將嘉、永吉真子
    • Organizer
      第33回日本疫学会学術総
    • Invited
  • [Presentation] 大豆製品およびイソフラボン摂取量と糖尿病罹患との関連:J-MICC Study2023

    • Author(s)
      釜野桜子、有澤孝吉、石津 将、渡邊 毅、Nguyen Van Tien、for the J-MICC Study Group
    • Organizer
      第33回日本疫学会学術総会
  • [Presentation] 東日本大震災後の精神的苦痛と避難経験の循環器疾患との関連に及ぼす出産経験の影響:福島県県民健康調査2023

    • Author(s)
      安川 純代,江口 依里,林 史和,大平 哲也,前田 正治,坂井 晃,島袋 充生,藤森 敬也,針金 まゆみ,安村 誠司,矢部 博興, 神谷 研二
    • Organizer
      第33回日本疫学会学術総会
  • [Presentation] 日本人女性における月経状況と動脈スティフネスとの関連:J-MICC Study徳島地区調査2023

    • Author(s)
      上村浩一、釜野桜子、有澤孝吉
    • Organizer
      第93回日本衛生学会学術総会
  • [Presentation] 日本人中高年における食物摂取頻度調査票の妥当性の検討-利用可能炭水化物2023

    • Author(s)
      篠壁多恵、今枝奈保美、後藤千穂、中村洋子、尾瀬功、細野晃弘、永吉真子、宮川尚子、尾崎悦子、池崎裕昭、南里妃名子、指宿りえ、釜野桜子、栗木清典、栗原綾子、矢口友理
    • Organizer
      第33回日本疫学会学術総会
  • [Presentation] 肺がんの新規バイオマーカー、治療標的分子 URST1 の同定2023

    • Author(s)
      高野 淳、宮城 洋平、醍醐 弥太郎
    • Organizer
      第20回日本臨床腫瘍学会
  • [Presentation] A lncRNA associated with chronic gastritis and gastric cancer inhibits apoptosis through stress granule formation2022

    • Author(s)
      Hiroshi Kitajima, Reo Maruyama, Akira Takasawa, Takeshi Niinuma, Eiichiro Yamamoto, Masahiro Kai, Makoto Osanai, Takashi Tokino, Hiroshi Nakase, Hiromu Suzuki
    • Organizer
      The 40th Sapporo International Cancer Symposium
    • Int'l Joint Research
  • [Presentation] A lncRNA associated with chronic gastritis and gastric cancer promotes stress granule formation and inhibits apoptosis2022

    • Author(s)
      Hiroshi Kitajima, Reo Maruyama, Takeshi Niinuma, Akira Takasawa, Eiichiro Yamamoto, Masahiro Kai, Takashi Tokino, Hiroshi Nakase, Hiromu Suzuki
    • Organizer
      第23回日本RNA学会年会
  • [Presentation] Aberrant decrement of certain transcription factors regulating the ADAR2 gene ADARB1 underlies the pathogenic downregulation of ADAR2 in the spinal motor neurons of sporadic ALS patients2022

    • Author(s)
      Hirose N, Teramoto S, YamashitaT, Aizawa H, Kwak S
    • Organizer
      第45回日本分子生物学会年会
  • [Presentation] Anti-neuroinflammation effect of zonisamide in early Parkinson’s disease: A chronological PET study2022

    • Author(s)
      Tatsuhiro Terada, Tomoyasu Bunai, Takashi Matsudaira, Masamichi Yokokura,Takashi Konishi, Tomokazu Obi, Yasuomi Ouchi
    • Organizer
      第63回日本神経学会学術大会
  • [Presentation] APOE ε2ハプロタイプは血清尿酸値を増加させる2022

    • Author(s)
      小倉正恒、豊田優、河村優輔、中山昌喜、高田龍平、清水聖子、東野俊英、中嶌真由子、四ノ宮成祥、松尾洋孝
    • Organizer
      第55回日本痛風・尿酸核酸学会
  • [Presentation] Association Between Nonalcoholic Fatty Liver Disease Risk Alleles And Atherosclerosis2022

    • Author(s)
      Ikezaki H, Schaefer EJ, Murata M, Shimono N
    • Organizer
      AHA Scientific Sessions 2022
    • Int'l Joint Research
  • [Presentation] Association of dietary diversity with all-cause mortality is modified by body mass index in Japanese older adults: An age-specific prospective cohort study (NISSIN project).2022

    • Author(s)
      Takabayashi S, Hirata T, Zhao W, Kimura T, Ukawa S, Tsushita K, Wakai K, Tamakoshi A.
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] Association of serum superoxide dismutase activity and the incidence of colorectal cancer in a nested case-control study2022

    • Author(s)
      Adachi Y, Nojima M, Mori M, Kubo T, Yamano H, Sasaki Y, Nakase H, Endo T, Lin Y, Wakai K, and Tamakoshi A
    • Organizer
      第81回日本癌学会
  • [Presentation] Association with nutrient intake, genetic factor, and seasonal variation on adiponectin concentration by multiple imputation method.2022

    • Author(s)
      Kani M , Goto C, Kuriki K.
    • Organizer
      The 8th Asian Congress of Dietetics
    • Int'l Joint Research
  • [Presentation] Biochemical distinction CBD/PSP2022

    • Author(s)
      Hasegawa M
    • Organizer
      63rd Annual Meeting of the Japanese Society of Neurology
    • Invited
  • [Presentation] CAFsは食道癌における術前化学療法抵抗性の獲得に関与する2022

    • Author(s)
      野村美咲、山下和成、那須元美、阿部雅明、佐々木和教、橋本貴史、峯 真司、折茂 彰
    • Organizer
      第33回日本消化器癌発生学会総会
  • [Presentation] Characterization of OASEP1 as a biomarker and therapeutic target for oral cancer2022

    • Author(s)
      Atsushi Takano, Yoshihiro Yoshitake, Masanori Shinohara, Yataro Daigo
    • Organizer
      第81回日本癌学会
  • [Presentation] Characterization of OASEP1 as a biomarker and therapeutic target for oral cancer2022

    • Author(s)
      Atsushi Takano, Yoshihiro Yoshitake, Masanori Shinohara, Yataro Daigo
    • Organizer
      2022 AACR annual meeting
    • Int'l Joint Research
  • [Presentation] CRPによる炎症反応と主観的な睡眠時間との関連:J-MICC Study静岡地区2022

    • Author(s)
      森田えみ、久保陽子、永吉真子 、若井建志
    • Organizer
      日本睡眠学会第47回定期学術集会
  • [Presentation] Dissecting carcinogenic effects of ALDH2 rs671: new insights from causal mediation analysis2022

    • Author(s)
      小柳友理子、尾瀬功、春日井由美子、川勝雪乃、谷山祐香里、井本逸勢、伊藤秀美、松尾恵太郎
    • Organizer
      第81回日本癌学会学術総会
  • [Presentation] DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis2022

    • Author(s)
      Kyota Fujita, Hidenori Homma, Hikari Tanaka, Meihua Jin, Xiaocen Jin, Yong Huang, Yuki Yoshioka, Kanoh Kondo, Hiroki Shiwaku, Kazuhiko Tagawa, Hitoshi Okazaw
    • Organizer
      63rd Annual Meeting of the Japanese Society of Neurology
  • [Presentation] DNAジャイレース阻害剤ーTPP複合体によるmtDNA複製阻害を介した癌細胞の細胞死の誘導2022

    • Author(s)
      喬いく銘、木田裕貴、越川信子、竹永啓三
    • Organizer
      日本薬学会第142年会
  • [Presentation] Effect of YAP-dependent necrosis in the ultra early stage on Alzheimer's disease pathology2022

    • Author(s)
      Hikari Tanaka, Hidenori Homma, Kyota Fujita, Kanoh Kondo, Xiaocen Jin, Meihua Jin, Yuki Yoshioka, Sumire Takayama, Kazuhiko Tagawa, Hitoshi Okazawa
    • Organizer
      63rd Annual Meeting of the Japanese Society of Neurology
  • [Presentation] Evaluation of gut microbiome by data envelopment analysis (DEA) in the ME-BYO cohort2022

    • Author(s)
      Taizo Matsuki, Sho Nakamura, Minami Nishiyama, Hiroto Narimatsu
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] Evaluation of the risk of HTLV-1-associated diseases by analyzing the host immune responses2022

    • Author(s)
      山田 麻美、安永 純一朗、砂川 純也、中岡 慎治、岩見 真吾、木暮 泰寛、伊藤 勇太、片岡 圭亮、中川 正法、岩永 正子、内丸 薫、宇都宮 與、高 起良、渡邉 俊樹、野坂 生郷、松岡 雅雄
    • Organizer
      第84回日本血液学会学術集会
  • [Presentation] Factors that influence the sense of attachment to the community in the Japanese population.2022

    • Author(s)
      Ukawa S, Kato Y, Lee Y, Ohara K, Mori K
    • Organizer
      The 8th International Conference on Public Health 2022
    • Int'l Joint Research
  • [Presentation] Fluorescent biosensors for probing neuronal activity and signaling2022

    • Author(s)
      Masayuki Sakamoto
    • Organizer
      Cell Biology, Developmental Biology, and Systems Biology Course Meeting
    • Invited
  • [Presentation] FXYD3, a subunit of Na+ K+ pump, determines the root of triple-negative breast cancer stem-like cells2022

    • Author(s)
      Menjiao Li
    • Organizer
      第81回日本癌学会学術総会
  • [Presentation] FXYX3, a subunit of Na+ pump, determines the origin of triple-negative breast cancer stem-like cells,the preeminent driver of drug resistance”The 19th Stem Cell Research Symposium2022

    • Author(s)
      後藤典子
    • Organizer
      第19回幹細胞シンポジウム
    • Invited
  • [Presentation] Genome-wide polygenic risk score and lifestyle risk factors for hypertension among 11,252 Japanese individuals2022

    • Author(s)
      Ryosuke Fujii, Asahi Hishida, Masahiro Nakatochi, Yoshiki Tsuboi, Koji Suzuki, Takaaki Kondo, Kenji Takeuchi, Kenji Wakai, J-MICC Study group
    • Organizer
      European Society of Human Genetics 2022
    • Int'l Joint Research
  • [Presentation] HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer’s disease pathology.2022

    • Author(s)
      Hikari Tanaka, Kanoh Kondo, Kyota Fujita, Hidenori Homma, Kazuhiko Tagawa, Xiaocen Jin, Meihua Jin, Yuki Yoshioka, Sumire Takayama, Hitoshi Okazawa.
    • Organizer
      NEURO2022
    • Int'l Joint Research
  • [Presentation] HMSN-P 9例における上下肢筋肉MRI所見の検討2022

    • Author(s)
      城戸美和子、諏訪園秀吾、藤﨑なつみ、渡慶次裕也、大城咲、宮城朋、藤原善寿、渡嘉敷崇
    • Organizer
      第63回日本神経学会総会
  • [Presentation] Huntington病の臨床試験の現状と展望2022

    • Author(s)
      岡澤 均
    • Organizer
      第63回日本神経学会学術大会
    • Invited
  • [Presentation] Imaging voltage and biochemical signaling in vivo2022

    • Author(s)
      Masayuki Sakamoto
    • Organizer
      Merocyanine540/Flash meeting
    • Int'l Joint Research / Invited
  • [Presentation] Intake and Biomarkers of Metabolites in Cancer Epidemiology: Focusing on Branched-chain Amino Acids and Risk of Pancreatic Cancer2022

    • Author(s)
      Ryoko Katagiri
    • Organizer
      7th JCA-AACR Special Joint Conference The Latest Advances in Pancreatic Cancer Research: From Basic Science to Therapeutics
    • Int'l Joint Research / Invited
  • [Presentation] LINC02154は頭頸部扁平上皮がんにおいて細胞周期関連遺伝子とミトコンドリア関連遺伝子を抑制する2022

    • Author(s)
      新沼猛、関口翔平、岡崎史佳、北嶋洋志、吉戸文乃、萬顕、甲斐正広、宮﨑晃亘、鈴木拓
    • Organizer
      第81回日本癌学会学術総会
  • [Presentation] Long-term variability and change trend of systolic blood pressure and risk of type 2 diabetes mellitus in middle-aged Japanese.2022

    • Author(s)
      Song Z, He Y, Chiang C, Al-shoaibi A, Saif-Ur-Rahman KM, Mamun MR, Matsunaga M, Ota A, Li Y, Yatsuya H
    • Organizer
      第58回日本循環器病予防学会学術集会
  • [Presentation] Measures of long-term systolic blood pressure variability and their associations with the risk of incident type 2 diabetes mellitus.2022

    • Author(s)
      Song Z, He Y, Chiang C, Al-Shoaibi AAA, Saif-Ur-Rahman KM, Mamun MR, Aoyama A, Hirakawa Y, Matsunaga M, Ota A, Tamakoshi K, Li Y, Yatsuya H
    • Organizer
      The 29th Scientific Meeting of the International Society of Hypertension
    • Int'l Joint Research
  • [Presentation] Membrane CD30とSoluble CD30の二重解析によるCD30発現評価法の検討2022

    • Author(s)
      中島誠、川俣豊隆、南谷泰仁、宇都宮與、渡邉俊樹、内丸薫
    • Organizer
      第8回日本HTLV-1学会学術集会
  • [Presentation] Mendelian randomization analyses revealed that coffee consumption reduces gout risk independently of serum uric acid levels2022

    • Author(s)
      Akiyoshi Nakayama, Yuya Shirai, Yusuke Kawamura, Yu Toyoda, Masahiro Nakatochi, Seiko Shimizu, Nariyoshi Shinomiya, Yukinori Okada, Hirotaka Matsuo
    • Organizer
      European Crystal Network Workshop 2022
    • Int'l Joint Research
  • [Presentation] Microenvironment creates premalignant mammary tissues and therapy-resistant persistent tumor cells in breast cancer2022

    • Author(s)
      後藤典子
    • Organizer
      第81回日本癌学会学術総会
    • Invited
  • [Presentation] Mitochondrial complex I abnormalities is associated with tau pathology in Alzheimer’s disease2022

    • Author(s)
      Tatsuhiro TERADA, Joseph Therriault, Min Su Kang, Takashi Matsudaira, Tomokazu Obi, Hideo Tsukada, Pedro Rosa-Neto
    • Organizer
      NEURO2022
  • [Presentation] Mitochondrial dysfunction underlie neurodegeneration in Alzheimer’s disease: A PET study2022

    • Author(s)
      Tatsuhiro Terada, Joseph Therriault, Min Su Kang, Tharick Ali Pascoal, Gleb Bezgin, Tomokazu Obi, Hideo Tsukada, Pedro Rosa-Neto, Yasuomi Ouchi
    • Organizer
      13th congress of the world federation of nuclear medicine and biology
    • Int'l Joint Research
  • [Presentation] Mitochondrial dysfunction underlies neurodegeneration in Alzheimer’s disease2022

    • Author(s)
      寺田達弘、Joseph Therriault、松平敬史、小尾智一、Pedro Rosa-Neto、尾内康臣
    • Organizer
      第41回日本認知症学会学術集会
  • [Presentation] Mitochondrial dysfunction underlies neurodegeneration in Alzheimer’s disease: A PET study2022

    • Author(s)
      Tatsuhiro TERADA, Joseph Therriault, Takashi Matsudaira,Tomokazu Obi, Hideo Tsukada, Pedro Rosa-Neto, Yasuomi Ouchi
    • Organizer
      BRAIN CONNECT2022
    • Int'l Joint Research
  • [Presentation] Molecular mechanisms of formation and propagation of pathological proteins in neurodegenerative diseases.2022

    • Author(s)
      Hasegawa M
    • Organizer
      NEURO2022.
    • Invited
  • [Presentation] Neuropathological profile of 4-repeat tau in spinocerebellar ataxia type 8.2022

    • Author(s)
      Goichi Beck, Yuki Yonenobu, Rika Yamashita, Toru Iwaki, Shigeo Murayama, Hideki Mochizuki
    • Organizer
      International Congress of Parkinson’s Disease and Movement Disorders
    • Int'l Joint Research
  • [Presentation] Neuropathology of pure autonomic failure.2022

    • Author(s)
      Murayama S, Saito Y
    • Organizer
      2022 Annual Meeting of AANP
    • Int'l Joint Research
  • [Presentation] NRF2遺伝子多型:乳癌発症リスクに関与する新規バイオマーカー2022

    • Author(s)
      岡野泰子
    • Organizer
      第81回日本癌学会学術総会
  • [Presentation] OASEP1 as a biomarker and therapeutic target for oral cancer2022

    • Author(s)
      高野 淳、吉武 義弘、篠原 正徳、醍醐弥太郎
    • Organizer
      第81回日本癌学会
  • [Presentation] OAT10は腎臓に発現する生理学的に重要な尿酸輸送体である2022

    • Author(s)
      豊田優、高田龍平、河村優輔、中山昌喜、森本渓音、清水聖子、藤原慎、鳥羽美帆、菊池理園、四ノ宮成祥、小林靖、松尾洋孝
    • Organizer
      第16回トランスポーター研究会年会
  • [Presentation] PAPSS1遺伝子多型と肝機能異常との関連2022

    • Author(s)
      銀光、内藤真理子、塚本峰子、門松由佳、久保陽子、岡田理恵子、篠壁多恵、川合紗世、田村高志、菱田朝陽、竹内研時、若井建志、浜島信之
    • Organizer
      第32回疫学会学術総会
  • [Presentation] Relationship between green tea intake and human gut microbiota on glucose metabolism: a four-season nutritional survey2022

    • Author(s)
      Ito A, Tachibana H, Kawashima A, Kawabata H, Goto C, Kuriki K
    • Organizer
      22nd International Union of Nutritional Sciences - International Congress of Nutrition
    • Int'l Joint Research
  • [Presentation] Relationship Between the Cholesterol and Triglyceride Content of Lipoprotein Subclasses and Carotid Intima-Media Thickness: Results from the Kyushu and Okinawa Population Study2022

    • Author(s)
      Ikezaki H, Ai M, Okazaki M, Hayashi J, Shimono N, Schaefer EJ
    • Organizer
      90th EAS Congress
    • Int'l Joint Research
  • [Presentation] SCA8関連筋萎縮性側索硬化症の臨床病理学的解析と細胞モデルの構築および治療法の検討2022

    • Author(s)
      平野牧人、竹原俊幸、村山繁雄、和泉唯信、寒川 真、松原知康、斎藤祐子、西郷和真、中村雄作、楠 進、永井義隆
    • Organizer
      第40回日本神経治療学会
  • [Presentation] The function of NK cells can be recovered by Va24+ NKT cell activation in cervical cancer patients.2022

    • Author(s)
      Yuhya Hirahara, Tomonori Iyoda, Kanako Shimizu, Etsuko Miyagi, and Shin-ichiro Fujii
    • Organizer
      第81回日本癌学会
  • [Presentation] TPP結合DNAジャイレース阻害剤によるmtDNA複製阻害を介したがん細胞の増殖阻害2022

    • Author(s)
      喬いく銘、木田裕貴、渡辺隆義、越川信子、竹永啓三
    • Organizer
      第81回日本癌学会学術総会
  • [Presentation] URAT1/SLC22A12遺伝子の機能低下型変異は痛風発作を強力に抑制する2022

    • Author(s)
      鳥羽美帆、豊田優、河村優輔、中山昌喜、中岡博史、東野俊英、清水聖子、堀江美音、田中里沙、大山博司、若井建志、鈴木洋史、四ノ宮成祥、高田龍平、松尾洋孝
    • Organizer
      第67回防衛衛生学会
  • [Presentation] URAT1遺伝子の機能低下型変異による痛風の保護効果は、ABCG2遺伝子の機能低下型変異による痛風のリスク亢進効果を上回る2022

    • Author(s)
      豊田優、河村優輔、中山昌喜、東野俊英、清水聖子、大山博司、市田公美、四ノ宮成祥、高田龍平、松尾洋孝
    • Organizer
      第55回日本痛風・尿酸核酸学会
  • [Presentation] Wnt 経路に変異を持つ腸管腫瘍細胞において MyD88 の機能抑制が合成致死をもたらすメカニズムの解明2022

    • Author(s)
      梶野リエ、藤下晃章、武藤誠、青木正博
    • Organizer
      第81回日本癌学会学術総会
  • [Presentation] αシヌクレインの構造とSpreading2022

    • Author(s)
      長谷川成人
    • Organizer
      第12回日本小脳学会学術集会・総会
    • Invited
  • [Presentation] アルツハイマー病のミトコンドリア障害は糖代謝、脳萎縮、認知機能障害と関連する2022

    • Author(s)
      寺田達弘、Joseph Therriault、松平敬史、小尾智一、塚田秀夫、Pedro Rosa-Neto、尾内康臣
    • Organizer
      第65回日本脳循環代謝学会学術集会
  • [Presentation] アルツハイマー病剖検脳でのスフィンゴ脂質、グリセロリン脂質の変動2022

    • Author(s)
      蔵野 信、齊藤 祐子、矢冨 裕
    • Organizer
      第44回日本医用マススペクトル学会年会
  • [Presentation] がん幹細胞の親Root-CSCsはDrug-tolerant persistersである2022

    • Author(s)
      後藤典子
    • Organizer
      第12回シグナルネットワーク研究会
    • Invited
  • [Presentation] がん転移におけるS100A8/A9の機能解明とその制御-HRGの発見による新展開-2022

    • Author(s)
      阪口政清
    • Organizer
      日本血液製剤機構(JB)招待講演
    • Invited
  • [Presentation] ゲノム安定性を制御する長鎖非翻訳RNA2022

    • Author(s)
      鈴木 美穂.飯島 健太.新城 恵子.近藤 豊
    • Organizer
      第81回日本癌学会学術総会.インターナショナルセッション
    • Invited
  • [Presentation] コーヒーは尿酸値とは無関係に痛風リスクを減らす:ゲノムワイド関連解析の結果を用いたメンデルランダム化解析から2022

    • Author(s)
      中山昌喜、白井雄也、河村優輔、豊田優、中杤昌弘、清水聖子、四ノ宮成祥、岡田随象、松尾洋孝
    • Organizer
      第40回日本ヒト細胞学会学術集会
  • [Presentation] コーヒー摂取と代謝表現型:J-MICC Studyのベースラインデータを用いた横断研究2022

    • Author(s)
      渡邊毅、有澤孝吉、Tien Van Nguyen、石津将、釜野桜子 for the J-MICC Study Group
    • Organizer
      第33回日本疫学会学術総会
  • [Presentation] タウ、αシヌクレイン、TDP-43凝集体の立体構造2022

    • Author(s)
      長谷川成人
    • Organizer
      第41回日本認知症学会学術集会 第37回日本老年精神医学会 合同開催
    • Invited
  • [Presentation] トランスポゾンマウスを用いた大腸がん転移関連遺伝子の生体スクリーニング2022

    • Author(s)
      藤下晃章、梶野リエ、三城恵美、武藤誠、青木正博
    • Organizer
      第81回日本癌学会学術総会
  • [Presentation] トリプルネガティブタイプ乳がん臨床検体のスフェロイド培養から明らかになってきた「親玉がん幹細胞」2022

    • Author(s)
      後藤典子
    • Organizer
      日本患者由来がんモデル学会
    • Invited
  • [Presentation] トリプルネガティブタイプ乳がん臨床検体のスフェロイド培養から明らかになってきた「親玉がん幹細胞」2022

    • Author(s)
      後藤典子
    • Organizer
      第4回がん三次元培養研究会
    • Invited
  • [Presentation] トリプルネガティブ乳がん幹細胞の起源ルミナル前駆細胞は、Na+ポンプFXYD3を利用し抗がん剤耐性を獲得する2022

    • Author(s)
      Menjiao Li
    • Organizer
      第26回日本がん分子標的治療学会学術集会
  • [Presentation] ヒト大腸癌オルガノイドと繊維芽細胞のマウス共移植モデルによる実験的CAFsの作製2022

    • Author(s)
      加藤祐子、目澤義弘、阿部雅明、陳 経権、水越幸輔、岡澤 裕、坂本一博、折茂 彰
    • Organizer
      第33回日本消化器癌発生学会総会
  • [Presentation] ヒト剖検脳におけるAD、LATE、PARTの感受性バリアント解析2022

    • Author(s)
      宮下 哲典、金田 大太、原 範和、月江 珠緒、長谷川 舞衣、春日 健作、橋詰 良夫、池内 健
    • Organizer
      第41回(2022年)日本認知症学会学術集会
  • [Presentation] プリオン病 再考 早期診断の視点から2022

    • Author(s)
      佐藤 克也
    • Organizer
      第41回日本認知症学会学術集会
    • Invited
  • [Presentation] ブロモドメインタンパク質BRD8を標的とした新たな大腸がん治療戦略2022

    • Author(s)
      山口 貴世志, 中川 沙弥, 高根 希世子, 池上 恒雄, 山口 類, 井元 清哉, 宮野 悟, 古川 洋一
    • Organizer
      第81回日本癌学会学術総会
  • [Presentation] ベーチェット病 機械学習を用いたBehcet病患者の免疫学的サブセットの検討2022

    • Author(s)
      平原 理紗, 桐野 洋平, 飯塚 友紀, 副島 裕太郎, 吉見 竜介, 藤枝 雄一郎, 渥美 達也, 東野 俊洋, 廣畑 俊成, 小林 大介, 中島 秀明
    • Organizer
      日本リウマチ学会総会・学術集会プログラム・抄録集 66回 330-330 2022年3月
    • Int'l Joint Research
  • [Presentation] マウスモデルを用いた大腸がんの幹細胞性・転移形成能に関与するシグナル経路の解析2022

    • Author(s)
      青木正博、武藤誠、藤下晃章
    • Organizer
      第26回日本がん分子標的治療学会
  • [Presentation] マウス一次視覚野におけるfast-spiking抑制性細胞-錐体細胞間結合の発達2022

    • Author(s)
      山本真理子, 岩里琢治, 吉村由美子
    • Organizer
      第45回日本神経科学大会
  • [Presentation] 胃炎・胃がん関連lncRNAはストレス顆粒形成を促進し、アポトーシスを抑制する2022

    • Author(s)
      北嶋洋志、丸山玲緒、新沼 猛、髙澤 啓、山本英一郎、石黒一也、吉戸文乃、甲斐正広、小山内誠、時野隆至、仲瀬裕志、鈴木 拓
    • Organizer
      第45回日本分子生物学会年会
  • [Presentation] 胃炎・胃がん関連長鎖non-coding RNAはストレス顆粒形成を促進してアポトーシスを抑制する2022

    • Author(s)
      北嶋洋志、丸山玲緒、新沼猛、高澤啓、山本英一郎、石黒一也、吉戸文乃、甲斐正広、小山内誠、時野隆至、仲瀬裕志、鈴木拓
    • Organizer
      第81回日本癌学会学術総会
  • [Presentation] 遺伝性ATTRアミロイドーシス(E61K変異)の1剖検例2022

    • Author(s)
      別宮 豪一、米延 友希、河井 真季子、池中 建介、大薗 達彦、島田 勇毅、山下 里佳、森井 英一、村山 繁雄、望月 秀樹
    • Organizer
      第48回臨床神経病理懇話会
  • [Presentation] 医師と製薬企業の関係に対する一般市民の捉え方と医師への信頼2022

    • Author(s)
      齋藤さやか、向原圭、室谷健太、下村一景
    • Organizer
      第54回日本医学教育学会大会
  • [Presentation] 医師を対象とした医師・製薬企業関係に関する調査研究:2008年から2021年における変化2022

    • Author(s)
      齋藤さやか、向原圭、室谷健太、下村一景
    • Organizer
      第54回日本医学教育学会大会
  • [Presentation] 一般住民におけるMKL1遺伝子のDNAメチル化率と肝機能検査値および肝疾患死亡との関連2022

    • Author(s)
      坪井良樹、山田宏哉、藤井亮輔、石原裕也、服部裕次、渡邊真巳、橋本修二、浜島信之、鈴木康司
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] 沖縄型神経原性筋萎縮症における肺活量の継時的変化の検討2022

    • Author(s)
      藤崎なつみ、諏訪園秀吾
    • Organizer
      第63回日本神経学会総会
  • [Presentation] 沖縄型神経原性筋萎縮症患者における両上肢への単関節HALの試験的導入と今後の課題2022

    • Author(s)
      速水慶太,橋口祐輔, 中川恵嗣, 与古田巨海, 諏訪園秀吾
    • Organizer
      第76回国立病院総合医学会
  • [Presentation] 回帰木分析を用いたロコモティブシンドロームと腸内細菌との関連解析2022

    • Author(s)
      西山未南, 中村翔, 松木大造, 成松宏人
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] 空間的プロファイリング技術を用いた精神疾患の病態解明の試み2022

    • Author(s)
      久保健一郎
    • Organizer
      第45回日本神経科学大会/第65回日本神経化学会大会/第32回日本神経回路学会大会
    • Invited
  • [Presentation] 血液バイオマーカーが拓く大腸がん検診の近未来2022

    • Author(s)
      田口 歩
    • Organizer
      JDDW2022
    • Invited
  • [Presentation] 血清スーパーオキシドディスムターゼ(SOD)活性と食道癌罹患リスク2022

    • Author(s)
      足立靖, 野島正寛, 森満, 久保俊之, 佐々木泰史, 仲瀬裕志, 遠藤高夫, 林櫻松, 若井建志, 玉腰暁子
    • Organizer
      第33回日本消化器癌発生学会
  • [Presentation] 血清トコフェロール値と白血球SOCS3遺伝子のDNAメチル化率との関連-Yakumo Study-2022

    • Author(s)
      鈴木康司、山田宏哉、藤井亮輔、坪井良樹、石原裕也、服部裕次、渡邊真巳、橋本修二、浜島信之
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] 口腔がんの新規バイオマーカー、治療標的分子 OASEP1 の機能解析2022

    • Author(s)
      高野 淳、吉武 義弘、篠原 正徳、醍醐 弥太郎
    • Organizer
      第81回日本癌学会
  • [Presentation] 甲状腺濾胞癌の術前分子診断を可能とする新規バイオマーカー候補の有用性評価2022

    • Author(s)
      宮本凌太朗, 奥村晃大, 軸薗智雄, 杉谷巌, 乾隆, 石橋宰
    • Organizer
      第95回(2022年)日本生化学会大会
  • [Presentation] 高齢者ブレインバンク年次報告2022

    • Author(s)
      Matsubara T, Murayama S, Ihara R, (8名)Ishibashi K, Toyohara J, Saito Y, Ishii K:
    • Organizer
      第63回日本神経学会学術大会
  • [Presentation] 四季変動を考慮した肥満に対する高たんぱく質食品摂取量と腸内細菌叢の関連.2022

    • Author(s)
      川島晃子、川畑春佳、橘 拓希、伊東 葵、後藤千穂、栗木清典
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] 子宮頸癌におけるNK細胞機能の回復2022

    • Author(s)
      平原裕也,伊豫田智典,清水佳奈子,宮城悦子,藤井眞一郎
    • Organizer
      第21回日本婦人科がん分子標的研究会
  • [Presentation] 若手研究者の神経再生への挑戦~ダイレクトリプログラミングは本当に可能か~2022

    • Author(s)
      松田泰斗
    • Organizer
      8回TRF研究会
    • Invited
  • [Presentation] 住民健診受診者における白血球SOCS3遺伝子のDNAメチル化率が高血圧発症に及ぼす影響2022

    • Author(s)
      渡邊真巳、山田宏哉、藤井亮輔、坪井良樹、石原裕也、橋本修二、浜島信之、鈴木康司
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] 職業性ストレスと退職後の認知機能低下に関する縦断的研究 愛知職域コホート研究2022

    • Author(s)
      中島啓裕, 江啓発, 平川仁尚, He Yupeng, 霜田真子, 玉腰浩司, 八谷寛
    • Organizer
      第29回日本産業ストレス学会
  • [Presentation] 神経障害性を持つ非ヒト型シアル酸分子種のアルツハイマー病に対する影響の解明2022

    • Author(s)
      荻野加奈子、南 彰、中尾初音、平林義雄、紅林佑希、高橋忠伸、竹内英之
    • Organizer
      日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2022
  • [Presentation] 神経変性疾患における異常タンパク質の伝播機構2022

    • Author(s)
      長谷川成人
    • Organizer
      第63回日本神経病理学会総会学術研究会
    • Invited
  • [Presentation] 腎性低尿酸血症の原因遺伝子URAT1/SLC22A12の日本人30,685名における臨床遺伝学的解析:実際的診断に向けて2022

    • Author(s)
      河村優輔、中山昌喜、清水聖子、豊田優、染谷真澄、小田悠太、鳥羽美帆、川口真、鈴木聡子、岩澤聡子、中島宏、高田龍平、角田正史、有澤幸吉、嶽崎俊郎、田中恵太郎、市田公美、若井建志、四ノ宮成祥、松尾洋孝
    • Organizer
      日本人類遺伝学会第67回大会
  • [Presentation] 腎臓における尿酸輸送体としてのOAT10の分子生理学的理解2022

    • Author(s)
      豊田優、高田龍平、河村優輔、中山昌喜、森本渓音、清水聖子、四ノ宮成祥、小林靖、松尾洋孝
    • Organizer
      第95回日本生化学会大会
  • [Presentation] 早期パーキンソン病におけるゾニサミドの神経保護効果:分子画像に基づく縦断的検討2022

    • Author(s)
      寺田達弘、武内智康、橋爪孝典、松平敬史、横倉正倫、小西高志、小尾智一、尾内康臣
    • Organizer
      第40回日本神経治療学会学術集会
  • [Presentation] 大腸がんの幹細胞性と転移能に重要な腫瘍微小環境関連シグナル経路の解明2022

    • Author(s)
      青木正博、武藤誠、藤下晃章
    • Organizer
      第81回日本癌学会学術総会
  • [Presentation] 大腸がん低酸素領域限定的な可溶性IL-33受容体発現の回復は腫瘍の増殖と転移を抑制する2022

    • Author(s)
      秋元美穂、竹永啓三
    • Organizer
      第18回がんとハイポキシア研究会
  • [Presentation] 大脳新皮質に広範かつ層状に広がるTDP病理が特徴的であったFTD-MND/ALSDの一例2022

    • Author(s)
      山下 里佳、矢田 知大、山田 敏雅、米延 友希、別宮 豪一、長谷川 成人、森井 英一、森悦朗、村山 繁雄、望月 秀樹
    • Organizer
      第63回日本神経病理学会総会学術研究会
  • [Presentation] 中心前回に高度の変性とTDP病理を伴った意味性認知症の一剖検例2022

    • Author(s)
      米延 友希、繁信 和恵、田原 紳一郎、別宮 豪一、森井 英一、村山 繁雄、望月 秀樹
    • Organizer
      第23回日本神経病理学会近畿地方会
  • [Presentation] 中年期の牛乳摂取と老年期フレイル発症の関連2022

    • Author(s)
      洪英在, 宋澤安, 霜田真子, He Yupeng, 李媛英, 松永眞章, 中野嘉久, 江啓発, 平川仁尚, 太田充彦, 玉腰浩司, 八谷寛.
    • Organizer
      第68回東海公衆衛生学会学術大会
  • [Presentation] 中年期男性の20歳からの体重変化と老年期フレイル発症の関連2022

    • Author(s)
      洪英在、江啓発、平川仁尚、太田充彦、玉腰浩司、八谷寛
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] 糖尿病関連指標に対する血糖値の調節に関わる遺伝的要因と栄養素摂取量の関連.2022

    • Author(s)
      橘 拓希、川島晃子、川畑春佳、伊東 葵、後藤千穂、栗木清典
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] 内臓脂肪面積に対する脂肪酸摂取量と赤血球膜脂肪酸構成割合、遺伝的要因の季節の関連.2022

    • Author(s)
      川畑春佳、川島晃子、橘 拓希、伊東 葵、後藤千穂、栗木清典
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] 日本人コホート集団30,685人を対象とした腎性低尿酸血症の臨床遺伝疫学的解析:実際的診断に向けて2022

    • Author(s)
      河村優輔、中山昌喜、 豊田優、西田裕一郎、菱田朝陽、釜野桜子、渋谷謙一、田村高志、中島宏、指宿りえ、上村浩一、原めぐみ、竹内研時、角田正史、有澤幸吉、嶽崎俊郎、田中恵太郎、若井建志、四ノ宮成祥、松尾洋孝
    • Organizer
      第32回日本疫学会学術総会
  • [Presentation] 日本人を対象としたX染色体ワイドメタ解析による尿酸関連SNP rs3020789の同定2022

    • Author(s)
      中杤昌弘、豊田優、中山昌喜、河村優輔、四ノ宮成祥、松尾洋孝
    • Organizer
      第55回日本痛風・尿酸核酸学会
  • [Presentation] 日本人集団3万人における尿酸再吸収輸送体遺伝子URAT1/SLC22A12の機能消失型変異がもたらす影響についての臨床遺伝学的検討2022

    • Author(s)
      中山昌喜、河村優輔、豊田優、清水聖子、染谷真澄、田中里沙、森友理乃、今給黎敏彦、岩澤聡子、中島宏、角田正史、伊藤敬一、有澤孝吉、嶽崎俊郎、田中恵太郎、高田龍平、市田公美、若井建志、四ノ宮成祥、松尾洋孝
    • Organizer
      第16回トランスポーター研究会年会
  • [Presentation] 乳がんの微小環境ニッチと腫瘍不均一性解明による新たな標的治療の可能性2022

    • Author(s)
      後藤典子
    • Organizer
      第32回日本サイトメトリー学会学術集会
    • Invited
  • [Presentation] 尿酸輸送体遺伝子URAT1/SLC22A12の機能消失型変異の低尿酸血症への影響: 日本人4,993名の分子疫学的解析から2022

    • Author(s)
      堀江美音、中山昌喜、河村優輔、豊田優、清水聖子、川口真、青木優佳、藤原慎、竹内研時、今給黎敏彦、岩澤聡子、中島宏、角田正史、伊藤敬一、熊谷裕生、市田公美、四ノ宮成祥、松尾洋孝
    • Organizer
      第67回防衛衛生学会
  • [Presentation] 尿中尿酸排泄率と血清尿酸値の特徴的な分布パターンに基づく腎性低尿酸血症の実践的な診断モデルの提案:日本人30685人を対象とした臨床遺伝疫学的解析より2022

    • Author(s)
      河村優輔、中山昌喜、豊田優、川口真、高田雄三、清水聖子、高田龍平、市田公美、四ノ宮成祥、松尾洋孝
    • Organizer
      第55回日本痛風・尿酸核酸学会
  • [Presentation] 妊娠中に発症し良好な転機をたどった免疫介在性壊死性ミオパチーの1例2022

    • Author(s)
      別宮 豪一、林 友豊、大薗 達彦、米延 友希、山下 里佳、池中 建介、奥野 龍禎、村山 繁雄、望月 秀樹
    • Organizer
      第63回日本神経病理学会総会学術研究会
  • [Presentation] 脳深部刺激療法(DBS)の電極刺入部にタウ沈着が見られたパーキンソン病の一例2022

    • Author(s)
      米延 友希、右近 琴、別宮 豪一、木下 福章、山下 里佳、森井 英一、村山 繁雄、望月 秀樹
    • Organizer
      第63回日本神経病理学会総会学術研究会
  • [Presentation] 肺がんの新規予後マーカー、治療標的分子URST1の同定2022

    • Author(s)
      高野 淳、宮城 洋平、醍醐 弥太郎
    • Organizer
      第68回日本人類遺伝学会
  • [Presentation] 慢性胃炎・胃がん関連長鎖non-coding RNAはストレス顆粒形成を促進し、アポトーシスを抑制する2022

    • Author(s)
      北嶋洋志、丸山玲緒、新沼 猛、高澤 啓、石黒一也、甲斐正広、吉戸文乃、小山内誠、時野隆至、仲瀬裕志、鈴木 拓
    • Organizer
      第15回日本エピジェネティクス研究会年会
  • [Presentation] 夜間の睡眠時間及び昼寝と大動脈疾患死亡との関連:the JACC Study2022

    • Author(s)
      清水望,陣内裕成,加藤活人,山岸良匡,木原朋未,高田碧,大塚俊昭,玉腰暁子,磯博康
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] 緑茶、コーヒー、紅茶及びウーロン茶摂取と慢性腎臓病死亡との関連:The JACC Study2022

    • Author(s)
      郭帥,山岸良匡,木原朋未,玉腰曉子,磯博康
    • Organizer
      第81回日本公衆衛生学会総会
  • [Presentation] 老化脳に蓄積する脳希少糖はアミロイド凝集を促進する2022

    • Author(s)
      荻野 加奈子、南 彰、中尾 初音、平林 義雄、紅林 佑希、高橋 忠伸、竹内 英之
    • Organizer
      第37回SAM学会学術大会
  • [Remarks] 生命科学連携推進協議会

    • URL

      https://square.umin.ac.jp/platform/

  • [Remarks] コホート・生体試料支援プラットフォーム

    • URL

      https://square.umin.ac.jp/cohort/

  • [Patent(Industrial Property Rights)] 甲状腺濾胞癌特異的マーカー2022

    • Inventor(s)
      軸薗智雄、石橋宰
    • Industrial Property Rights Holder
      日本医科大学、大阪公立大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      PCT/JP2022/015687
    • Overseas
  • [Patent(Industrial Property Rights)] 血清試料検査装置、及び血清試料の検査方法2022

    • Inventor(s)
      伊藤寛晃, 宮崎智和
    • Industrial Property Rights Holder
      伊藤寛晃
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      特許第7129732号

URL: 

Published: 2023-12-25   Modified: 2024-12-25  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi