2013 Fiscal Year Final Research Report
Development for radio frequency ablation supporting system appropriate to coagulation area of tumor by clarifying coagulation mechanism
| Project/Area Number |
23240081
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Waseda University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI Yo 早稲田大学, 理工学術院, 准教授 (50424817)
SATO Yoshinobu 大阪大学, 医学(系)研究科(研究院), 准教授 (70243219)
HASHIZUME Makoto 九州大学, 医学(系)研究科(研究院), 教授 (90198664)
FUJIE Masakatsu 早稲田大学, 理工学術院, 教授 (20339716)
HOSHI Takeharu 早稲田大学, 理工学術院, 講師 (50535284)
MIYASHITA Tomoyuki 早稲田大学, 理工学術院, 教授 (20329080)
WATANABE Hiroki 早稲田大学, 理工学術院, 助手 (00609266)
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| Project Period (FY) |
2011-05-31 – 2014-03-31
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| Keywords | 癌凝固メカニズム / 電磁波熱治療 / 生体熱力学 / バイオメカトロニクス / シミュレーション |
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| Research Abstract |
In order to provide the accuracy of radio frequency ablation (RFA) treatment we proposed a RFA supporting treatment system. We mainly focused on the problems of RFA treatment and proposed the solutions such as (1) clarify the mechanism of coagulation in RFA and (2) develop the temperature distribution simulator based coagulation condition. We employed both mechanical method and biology method to make analyze the coagulation condition and evaluate the experimental results. According to the in vitro experiments, we found that the viscoelasticity of tissue in RFA treatment was useful as the index of coagulation condition and modeled the temperature dependence of viscoelasticity. And we used both mechanical method and biology method to derive and evaluate the parameters of ablation condition, which determined the coagulation condition of tissue. We also validated the bio-heat transfer model in RFA and developed the temperature distribution numerical simulator for RFA.
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[Presentation] A Method for Distinguishing Coagulation Boundary Tmeperature in liver Tissue for RF Ablation2012
Author(s)
XiaoWei Lu, Mariko Tsukune, Nozomu Yamazaki, Hiroki Watanabe, Yo Kobayashi, Tomoyuki Miyashita, Takashi Kakimoto, Hiromasa, Yamashita, Toshio Chiba, Masakatsu G. Fujie
Organizer
The 8th Asian Conference on Computer Aided Surgery (ACCAS 2012)
Place of Presentation
Beijing, China
Year and Date
20120500
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