2013 Fiscal Year Final Research Report
Enzymatic synthesis of useful chemicals from nitrogen-containg substrates
| Project/Area Number |
23248015
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Toyama Prefectural University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KOMEDA Hidenobu 富山県立大学, 工学部, 准教授 (50285160)
FUHSHUKU Ken-ichi 富山県立大学, 工学部, 助教 (70392090)
SUZUKI Atsuo 名古屋大学, 工学部, 准教授 (40196788)
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| Project Period (FY) |
2011-05-31 – 2014-03-31
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| Keywords | 光学分割 / 微生物酵素 / 植物酵素 / ラセマーゼ / 含窒素化合物 |
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| Research Abstract |
In this research, we characterized many plant and microbial enzymes acting on nitrogen containing compounds, found in their "Aldoxime-Nitrile Pathways", and utilized them in the synthesis of various useful chemicals. Most of the reactions they catalyze cannot be done in the synthetic chemical reactions. We utilized the following enzymes, such as nitrile hydratases, D- and L-stereospecific amino acid amidases, a-amino-e-aminocaprolactam racemase, plant hydroxynitrile lyases, etc., in the production of useful nitrogen containing compounds.
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[Presentation] Alteration of substrate specificity of ACL racemase from A.obae2011
Author(s)
S. Matsumura, S. Maruyama, M. Otsuka, K. Tokunan, K. Holsch, K. Suzuki, A. Suzuki, S. Okazaki, N. Watanabe, T. Yamane, H. Komeda and Y. Asano
Organizer
酵素工学研究会第66回講演会(2011)
Place of Presentation
東京
Year and Date
2011-09-29
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