2015 Fiscal Year Final Research Report
Implantable gcluose sensor toward fully implantable glucose monitoring system
Project/Area Number |
23360157
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Electron device/Electronic equipment
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Research Institution | Nara Institute of Science and Technology |
Principal Investigator |
Tokuda Takashi 奈良先端科学技術大学院大学, 物質創成科学研究科, 准教授 (50314539)
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Co-Investigator(Renkei-kenkyūsha) |
OHTA Jun 奈良先端科学技術大学院大学, 物質創成科学研究科, 教授 (80304161)
SASAGAWA Kiyotaka 奈良先端科学技術大学院大学, 物質創成科学研究科, 助教 (50392725)
NODA Toshihiko 奈良先端科学技術大学院大学, 物質創成科学研究科, 助教 (20464159)
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Research Collaborator |
TAKEUCHI Shoji 東京大学, 生産技術研究所, 教授 (90343110)
OKITSU Teru 東京大学, 生産技術研究所, 特任教授 (10378672)
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Project Period (FY) |
2011-04-01 – 2016-03-31
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Keywords | CMOS / 体内埋め込みデバイス / 血糖値計測 / バイオチップ / 糖尿病 |
Outline of Final Research Achievements |
An implantable glucose sensor was proposed and demonstrated. This sensor is designed based on a concept of fully-implantable glucose monitoring technology. We adopted a glucose-responsive fluorescent hydrogel as a mediator for the implantable glucose sensor. Integrating implantable CMOS imagesensor, fluorescent hydrogel, and mirco-light source (LED) we demonstrated the basic glucose sensing capability. We successfully demonstrated the sensing function in both in vitro and in vivo experiments. We also confirmed a device lifetime longer than 150 days.
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Free Research Field |
半導体光デバイス・バイオチップ
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