2013 Fiscal Year Final Research Report
Elucidating the signal transduction network regulating cell motility
| Project/Area Number |
23370085
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Cell biology
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
KATOH Hironori 京都大学, 生命科学研究科, 准教授 (50303847)
|
|---|
| Project Period (FY) |
2011-11-18 – 2014-03-31
|
| Keywords | 細胞・組織 / シグナル伝達 / 癌 / 脳・神経 |
|---|
| Research Abstract |
Cell migration contributes a variety of diseases including tumor metastasis and lymphocyte chemotaxis in allergic diseases. It is important to elucidate molecular mechanisms underlying the regulation of cell migration to provide new therapeutic targets. In this research, we focused on Rho family G proteins and their regulators, which play key roles in signal transduction pathways leading to regulation of cell migration, and found several novel signaling pathways and their interactions.
|
