Relationship between the selenium nutritional status and the depressive types classified with depression screening questionnaire and multi-channel near-infrared spectroscopy

2013 Fiscal Year Final Research Report

• Project/Area Number: 23390159
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Hygiene
• Research Institution: Gunma University
• Principal Investigator: KOYAMA Hiroshi 群馬大学, 医学(系)研究科(研究院), 教授 (30143192)
• Co-Investigator(Kenkyū-buntansha): KAMEO Satomi 群馬大学, 大学院・医学系研究科, 助教 (40312558) ; YAMAZAKI Chiho 群馬大学, 大学院・医学系研究科, 助教 (20506422) ; MIKUNI Masahiko 国際医療福祉大学, 教授 (00125353) ; NAKAZAWA Minato 神戸大学, 大学院・保健学研究科, 教授 (40251227)
• Co-Investigator(Renkei-kenkyūsha): FUKUDA Masato 群馬大学, 大学院・医学系研究科, 教授 (20221533)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Keywords: セレン / うつ / 質問紙調査票 / 光トポグラフィー / NIRS / 微量元素 / メンタルヘルス / GPｘ

Research Abstract

Depression has become a great social problem throughout the world. Various factors are relating to the depressive status, and selenium nutritional status may also cause the affective status.
A new depression screening questionnaire, the Kokoro Check Sheet (KCS), has been developed and used in this study.The objective of the present study was to divide the depressive subjects into several types of depression and analyze the association of selenium status. A total of 600 subjects in rural area and 1,500 subjects in working places were participated.The results of KCS shows approximately 5% of males and 6% of females were as depressive. Association of selenium to the depressive status and comparison of the grouping by KCS and by multi-channel near-infrared spectroscopy (NIRS) are the next step.

Research Products

• [Journal Article] Reduced serum selenium concentration in miscarriage incidence of Indonesian subjects (2013)
  • Author(s): Abdulah Rizky, Yamazaki Chiho, Nakazawa Minato, Koyama Hiroshi (他7名)
  • Journal Title: Biological trace element research Volume: 154(1) Pages: 1-6
  • Peer Reviewed
• [Journal Article] Association between selenium nutritional status and metabolic risk factors in men with visceral obesity (2013)
  • Author(s): Mutakin, Kobayashi Kenji, Yamazaki Chiho, Kameo Satomi, Nakazawa Minato, Koyama Hiroshi.(他2名 )
  • Journal Title: Journal of trace elements in medicine and biology Volume: 27(2) Pages: 112-116
  • Peer Reviewed
• [Journal Article] セレン補充によるがん予防と糖尿病発症リスク-SELECT研究とその後- (2013)
  • Author(s): 小山洋, MUTAKIN, Rizky Abdulah, 山崎千穂, 亀尾聡美
  • Journal Title: 日本衛生学会雑誌 Volume: 68(1) Pages: 1-10
  • Peer Reviewed
• [Journal Article] 群馬県農村部における抑うつ状態とライフスタイル要因との関連 -共分散構造分析を用いた「こころのチェックシート」の解析- (2012)
  • Author(s): 村山侑里, 山本林子, 山口美穂, 山崎千穂, 中澤港, 小山洋
  • Journal Title: 北関東医学会雑誌 Volume: 62(1) Pages: 41-51
  • Peer Reviewed
• [Journal Article] Molecular targets of selenium in prostate cancer prevention (2011)
  • Author(s): Abdulah Rizky, Kobayashi Kenji, Yamazaki Chiho, Koyama Hiroshi
  • Journal Title: International journal of oncology Volume: 39(2) Pages: 301-309
  • Peer Reviewed
• [Journal Article] Selenium-induced apoptosis-like cell death in Plasmodium falciparum (2011)
  • Author(s): Suradji Eka W, Hatabu Toshimitsu, Kobayashi Kenji, Yamazaki Chiho, Abdulah Rizky, Nakazawa Minato, Nakajima-Shimada J, Koyama Hiroshi
  • Journal Title: Parasitology Volume: 19 Pages: 1-11
  • Peer Reviewed
• [Journal Article] Acute phase response of selenium status and glutathione peroxidase activity in blood plasma before and after total knee arthroplasty surgery (2011)
  • Author(s): Defi Irma Ruslina, Yamazaki Chiho, Kameo Satomi, Kobayashi, Kenji, Nakazawa Minato, Shinya Yanagisawa, Sato Naoki, Wada Naoki, Shirakura Kenji, Koyama Hiroshi
  • Journal Title: Biological trace element research Volume: 144 Pages: 388-395
  • Peer Reviewed
• [Presentation] Fatigue related changes of selenium, zinc and copper in serum during continuous work loading process (2013)
  • Author(s): Satomi Kameo Hiroshi Koyama, 他3名
  • Organizer: 10th International Symposium on Selenium in Biology and Medicine
  • Place of Presentation: ドイツ・ベルリン
  • Year and Date: 20130914-18
• [Presentation] Selenium supplementation protects normal human esophageal cells against X-ray irradiation (2013)
  • Author(s): Irma Melyani Puspitasari Chiho Yanmazaki Satomi Kameo Hiroshi Koyama, 他 2名
  • Organizer: 10th International Symposium on Selenium in Biology and Medicine
  • Place of Presentation: ドイツ・ベルリン
  • Year and Date: 20130914-18
• [Presentation] Effect of the selenium supplementation on the plasma selenium and several biochemical indexes in Japanese healthy volunteers with different exercise habits (2011)
  • Author(s): 亀尾聡美 山崎千穂, 中澤港, 小山洋, 他6名
  • Organizer: International Society for Trace Element Research in Humans (IXth ISTERH)
  • Place of Presentation: トルコ・アンタルヤ
  • Year and Date: 20111016-22
• [Presentation] An ecological study of cardiovascular disease prevalence and selenium in Lampung-Indonesia (2011)
  • Author(s): Mutakin, Ida F. Rivai, Kobayashi Kenji, Yamazaki Chiho, Kameo Satomi, Nakazawa Minato, Koyama Hiroshi, 他3名
  • Organizer: IXth ISTERH
  • Place of Presentation: トルコ・アンタルヤ
  • Year and Date: 20111016-22
• [Presentation] Acute phase responses of plasma selenium against total knee arthroplasty surgery (2011)
  • Author(s): Irma Ruslina Defi, Yamazaki Chiho, Kameo Satomi, , Nakazawa Minato , Shirakura Kenji, Koyama Hiroshi, 他3名
  • Organizer: IXth ISTERH
  • Place of Presentation: トルコ・アンタルヤ
  • Year and Date: 20111016-22
• [Presentation] Effect of Probiotic L. plantarum IS-10506 and zinc supplementation on serum selenium concentrations and GPx activities of Indonesian pre-school Children (2011)
  • Author(s): Koyama Hiroshi Kameo Satomi , Ingrid S Surono, 他4名
  • Organizer: IXth ISTERH
  • Place of Presentation: トルコ・アンタルヤ
  • Year and Date: 2011-10-19