2013 Fiscal Year Final Research Report
Development of four-dimensional CT acquisition and tumor detection system during volumetric modulated arc therapy.
| Project/Area Number |
23390298
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
DEMACHI Kazuyuki 東京大学, 大学院・工学系研究科(工学部), 准教授 (00292764)
MASUTANI Yoshitaka 東京大学, 医学部附属病院, 講師 (20345193)
SAKUMI Akira 東京大学, 医学部附属病院, 特任助教 (30360556)
HAGA Akihiro 東京大学, 医学部附属病院, 助教 (30448021)
NISHIO Teiji 独立行政法人国立がん研究センター, 臨床開発センター, ユニット長 (40415526)
SHIRAISHI Kenshiro 東京大学, 医学部附属病院, 助教 (40447404)
YAMASHITA Hideomi 東京大学, 医学部附属病院, 助教 (70447407)
IGAKI Hiroshi 東京大学, 医学部附属病院, 講師 (90361344)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Keywords | VMAT / コーンビーム CT / 呼吸性移動 / 4D-CT / IMRT / VMAT-CT / radiation therapy |
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| Research Abstract |
In this study, we have developed in-treatment kilo-voltage four-dimensional cone-beam CT (in-treatment kV 4D CBCT) acquisition during volumetric modulated arc therapy (VMAT) by use of the image-based phase recognition technique of projection images. With the in-treatment kV 4D CBCT, the respiratory motion of lung tumors has been quantitatively evaluated for the first time, and the margin applied in treatment planning has been retrospectively reanalyzed. In addition, the CBCT reconstruction using the portal images of VMAT beam and its four dimensional version (4D VMAT CBCT) have been developed. With the 4D VMAT CBCT, the tumor location and movement were visually observed. Combining 4D VMAT CBCT with in-treatment kV 4D CBCT, it is expected that the appropriate margin setting and the reduction of the extra-radiation dose for normal tissue are achieved.
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Research Products
(23 results)
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[Journal Article] High-dose-rate intra-cavitary brachytherapy combined with external beam radiation therapy for under 40-year-old patients with invasive uterine cervical carcinoma : clinical outcomes in 118 Patients in a Japanese multi-institutional study, JASTRO2013
Author(s)
Yamashita H, Niibe Y, Toita T, Kazumoto T, Nishimura T, Kodaira T, Eto H, Kinoshita R, Tsujino K, Onishi H, Takemoto M, Hayakawa K
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Journal Title
Jpn J Clin Oncol
Volume: 43(5)
Pages: 547-52
DOI
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[Journal Article] Guidelines for respiratory motion management in radiation therapy2013
Author(s)
Matsuo Y, Onishi H, Nakagawa K, Nakamura M, Ariji T, Kumazaki Y, Shimbo M, Tohyama N, Nishio T, Okumura M, Shirato H, Hiraoka M
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Journal Title
J Radiat Res
Volume: 54(3)
Pages: 561-8
DOI
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[Journal Article] Dose verification of volumetric modulated arc therapy (VMAT) by use of in-treatment linac parameters2013
Author(s)
Haga A, Sakumi A, Okano Y, Itoh S, Saotome N, Kida S, Igaki H, Shiraishi K, Yamashita H, Ohtomo K, Nakagawa K
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Journal Title
Radiol Phys Technol
Volume: 6(2)
Pages: 335-42
DOI
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[Presentation] 放射線リスクコミュニケーションとリスク認知に関する研究2013
Author(s)
中川恵一, 黒田佑次郎, 坂田尚子, 作美明, 伴信彦, 坪野圭介, 岩満優美, 竹村和久, 水島希, 加瀬郁子, 佐倉統
Organizer
日本放射線影響学会第56会大会
Place of Presentation
青森
Year and Date
20131018-20
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