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2013 Fiscal Year Final Research Report

A study of practical suppression method of alternans using both mathematical and animal models.

Research Project

  • PDF
Project/Area Number 23500524
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionTokyo Metropolitan University

Principal Investigator

YAZAWA Toru  首都大学東京, 理工学研究科, 助教 (30106603)

Project Period (FY) 2011 – 2013
Keywords交互脈 / Alternans
Research Abstract

Alternans is called as harbinger of death rhythm, being well observable in a patient of ischemic heart disease. Mathematical model used my crab-heart data as a parameter of synaptic potentials. Then, the model could induce alternans, when extracellular potassium (K+) concentration was increased. I concluded that ionic concentration of K+ in the tissue fluid is a key factor to suppress generation of alternans.

  • Research Products

    (25 results)

All 2014 2013 2012 2011 Other

All Journal Article (11 results) Presentation (8 results) Book (5 results) Remarks (1 results)

  • [Journal Article] Alternans-Arrhythmia: A Simulation Study Based on Invertebrate Heart Neurobiology2014

    • Author(s)
      Yazawa, T., and Kitajima, H
    • Journal Title

      Proceedings IMCIC2014

      Pages: 184-189

  • [Journal Article] A Simulation Study of Alternans-Arrhythmia Based on Physiology of Invertebrate Heart2013

    • Author(s)
      Yazawa, T., and Kitajima, H., and Shimizu, A
    • Journal Title

      Proceedings of The World Congress on Engineering and Computer Science 2013

      Pages: 604-609

  • [Journal Article] Measurement of Stress Using DFA Heartbeat Analysis2013

    • Author(s)
      Yazawa, T., Hutapea, A. M., Otomura, Y., Sagawa, K., Yamada, Y., Suzuki, T., and Katsuyama, T
    • Journal Title

      Proceedings of The World Congress on Engineering and Computer Science 2013

      Pages: 596-603

  • [Journal Article] Athlete heartbeats engaged in ergometer exercise: A detrended fluctuation analysis checking the heart rhythm condition2012

    • Author(s)
      Yazawa, T., Hutapea, A., and Shimoda, Y
    • Journal Title

      Engineering Letters

      Volume: Vol. 20 Pages: 10-15

  • [Journal Article] Cardiac rhythm reflects mental condition as in chronic job stress: A detrended fluctuation analysis2012

    • Author(s)
      Hutapea, A. M., and Yazawa, T
    • Journal Title

      Proceedings, Fall 2012 IIIS Conference

      Volume: 1 Pages: 201-206

  • [Journal Article] Time Series Analysis of Heartbeat-Interval at the Subjects Ranging from Crustacean Animal to Human2012

    • Author(s)
      Yazawa, T., and Katsuyama, T
    • Journal Title

      Proceedings

      Pages: 94-99

  • [Journal Article] Neurodynamical control of the heart of freely moving animals including humans. Proceedings2012

    • Author(s)
      Yazawa, T., Shimoda, Y., Shimizu, S., and Katsuyama, T
    • Journal Title

      ASME 2012

      Pages: 1-10

  • [Journal Article] DFA Applied to the Neural-Regulation of the Heart2012

    • Author(s)
      Yazawa, T., and Shimoda, Y
    • Journal Title

      Proceedings

      Volume: 2 Pages: 715-720

  • [Journal Article] Analysis of a cardiac mathematical model for suppressing alternans2011

    • Author(s)
      Kitajima, H., and Yazawa, T
    • Journal Title

      IEICE Technical Report

      Pages: 61-64

  • [Journal Article] Detrended fluctuation analysis of arrhythmia: Scaling exponent as an index of heart wellness2011

    • Author(s)
      Yazawa, T., Hutapea, A., Katsuyama, T., and Shimoda, Y
    • Journal Title

      Proceedings ASME2011

      Pages: 10

  • [Journal Article] Quantification of athlete's heartbeats engaged in ergometer exercise: A detrended fluctuation analysis study checking the heart condition2011

    • Author(s)
      Yazawa, T., Hutapea, A., and Shimoda, Y
    • Journal Title

      Proceedings WCECS2011

      Volume: Vol. 2 Pages: 585-590

  • [Presentation] Alternans-Arrhythmia : A Simulation Study Based on Invertebrate Heart Neurobiology2014

    • Author(s)
      Yazawa, T., and Kitajima. H
    • Organizer
      The International Multi-Conference On Complexity And Cybernetics
    • Place of Presentation
      Orlando, FL, USA
    • Year and Date
      20140304-07
  • [Presentation] A Simulation Study of Alternans-Arrhythmia Based on Physiology of Invertebrate Heart2013

    • Author(s)
      Yazawa, T., Kitajima. H., and Shimizu, A
    • Organizer
      Proceedings of The World Congress on Engineering and Computer Science 2013
    • Place of Presentation
      UC Berkeley, CA, USA
    • Year and Date
      20131023-25
  • [Presentation] Measurements of stress by heartbeat analysis : an empirical work of DFA both in animal models and humans2013

    • Author(s)
      Yazawa, T
    • Organizer
      23rd Annual Conference Society for Chaos Theory in Psychology & Life Sciences
    • Place of Presentation
      Portland State University, Portland, Oregon, USA
    • Year and Date
      20130725-27
  • [Presentation] Neurodynamical control of the heart of freely moving animals including humans2012

    • Author(s)
      Yazawa, T
    • Organizer
      International Mechanical Engineering Congress & Exposition ASME 2012.
    • Place of Presentation
      Houston, Texas, USA
    • Year and Date
      20121109-15
  • [Presentation] DFA Applied to the Neural-Regulation of the Heart2012

    • Author(s)
      Yazawa, T
    • Organizer
      WCECS2012
    • Place of Presentation
      UC Berkely, CA, USA
    • Year and Date
      20121024-26
  • [Presentation] Scaling Exponent During Arrhythmia : Detrended Fluctuation Analysis is a Beneficial Biomedical Computation Tool2011

    • Author(s)
      Yazawa, T
    • Organizer
      International Mechanical Engineering Congress & Exposition ASME 2011
    • Place of Presentation
      Denver, Colorado, USA
    • Year and Date
      2011-11-16
  • [Presentation] Quantification of Athlete's Heartbeats Engaged in Ergometer Exercise : A Detrended Fluctuation Analysis Study Checking the Heart Condition2011

    • Author(s)
      Yazawa, T
    • Organizer
      International Conference on Computational Biology 2011
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2011-10-21
  • [Presentation] Detrended Fluctuation Analysis of Heartbeats While Engaging in Ergometer Exercise : Checking the Heart Condition by Numerical Quantification Method2011

    • Author(s)
      Yazawa, T
    • Organizer
      The 5th International Symposium on Bio- and Medical Informatics and Cybernetics (BMIC 2011)
    • Place of Presentation
      Orlando, FL, USA
    • Year and Date
      2011-07-20
  • [Book] Detrended Fluctuation Analysis : An Experiment about the Neural-Regulation of the Herat and Motor Vibration. IAENG Transactions on Engineering Technologies2014

    • Author(s)
      Yazawa, T., and Shimoda, Y
    • Publisher
      Springer Science+Business Media Dordrecht 2013(in press)
  • [Book] Quantification of Athlete's Heart Condition : A Detrended Fluctuation Analysis. In: IAENG Transactions on Engineering Technologies, Lecture Notes in Electrical Engineering2013

    • Author(s)
      Yazawa, T., Shimoda, Y., and Hutapea, A. M
    • Total Pages
      309-322
    • Publisher
      Springer Science +Business Media Dordrecht
  • [Book] DFA, a biomedical checking tool for the heart control system. In : Machine Learning and Systems Engineering2011

    • Author(s)
      Yazawa, T., Shimoda, Y., and Katsuyama, T
    • Total Pages
      547-556
  • [Book] Low Scaling Exponent during Arrhythmia : Detrended Fluctuation Analysis is a Beneficial Biomedical Computation Tool. In: Biomedical Engineering, Trends, Research and Technologies, Malgorzata Anna Komorowska and Sylwia Olsztynska-Janus (Eds.)2011

    • Author(s)
      Yazawa, T., and Shimoda, Y
    • Total Pages
      469-488
    • Publisher
      InTech
  • [Book] EVALUATION OF SLEEP BY DETRENDED FLUCTUATION ANALYSIS OF THE HEARTBEAT. In : IAENG Transactions on Engineering Technologies. S-L. Ao (Ed.)2011

    • Author(s)
      Yazawa, T., Shimoda, Y., and Hutapea, A
    • Total Pages
      199-210
    • Publisher
      American Institute of Physics, AIP Book
  • [Remarks]

    • URL

      http://www.tokyo-sangaku.jp/labo/%E7%9F%A2%E6%BE%A4-%E5%BE%B9/

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Published: 2015-07-16  

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