• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2013 Fiscal Year Final Research Report

Oxidative change of structures of herb polyphenols,investigation for their new functiality and safety

Research Project

  • PDF
Project/Area Number 23500929
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Eating habits, studies on eating habits
Research InstitutionThe University of Tokushima

Principal Investigator

MASUDA Toshiya  徳島大学, 大学院ソシオ・アーツ・アンド・サイエンス研究部, 教授 (10219339)

Project Period (FY) 2011 – 2013
KeywordsPolyphenols / Oxidation / Food Functionality / Food Safety / Structure Determination
Research Abstract

Recently, it becomes a social problem that structural change of active ingredients in functional foods causes harmful effects to humans such as carcinogenicity. Polyphenols are well known food functional compounds and are very oxidizable with their strong antioxidant properties. It should be noted that polyphenols should change easily during food cooking and manufacturing. Such instability of the polyphenols requires detailed analysis of alteration of their functions and evaluation of the new functions from the oxidized them. In this study, we clarified the functionality and chemical structures of the oxidized polyphenols from edible herbs. The obtained results indicated that oxidative change of polyphenols contributed to healthy life of humans by food intake.

  • Research Products

    (29 results)

All 2014 2013 2012 2011 Other

All Journal Article (12 results) (of which Peer Reviewed: 10 results) Presentation (14 results) Remarks (2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Chemical Evidence for Potent Xanthine Oxidase Inhibitory Activity of Glechoma hederacea var. garndis Leaves (Kakidoushi-Cha)2013

    • Author(s)
      Akiko Masuda, Chizuru Takahashi, Miyuki Inai, Yukari Miura and Toshiya Masuda
    • Journal Title

      Journal of Nutritional Science and Vitaminology

      Volume: Vol.59, No.6 Pages: 570-575

    • DOI

      10.1021/jf404357h

    • Peer Reviewed
  • [Journal Article] Enhancing Effect of a Cysteinyl Thiol on the Antioxidant Acrtivity of Flavonoids and Identification of Antioxidative Thiol-Adducts of Myricetin2013

    • Author(s)
      Toshiya Masuda, Yukari Miura, Miyuki Inai and Akiko Masuda
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: Vol.77, No.8 Pages: 1753-1758

    • DOI

      10.1271/bbb.130315

    • Peer Reviewed
  • [Journal Article] 四国地域で民間利用されている健康茶の機能(第一報)ラジカル消去, α-グルコシダーゼ阻害, キサンチンオキシダーゼ阻害活性について2013

    • Author(s)
      増田 晃子, 藤本 彩, 井内 智子, 高橋 千鶴, 稲井 美由紀, 三浦 ゆか理, 今井 昭二, 増田 俊哉
    • Journal Title

      日本食生活学会誌

      Volume: Vol.24 Pages: 11-20

    • DOI

      10.2740/jisdh.24.11

    • Peer Reviewed
  • [Journal Article] Effect of Polyphenols on Oxymyoglobin Oxidation : Prooxidant Activity of Polyphenols In Vitro and Inhibition by Amino Acids2013

    • Author(s)
      Toshiya Masuda, Miyuki Inai, Yukari Miura, Akiko Masuda and Satoshi Yamauchi
    • Journal Title

      Journal of Agricultural and Food Chemistry

      Volume: Vol.61 Pages: 1097-1104

    • DOI

      10.1021/jf304775x

    • Peer Reviewed
  • [Journal Article] Chemical Evidence for the Synergistic Effect of a Cysteinyl Thiol on the Antioxidant Activity of Caffeic and Dihydrocaffeic Esters2013

    • Author(s)
      Aya Fujimoto, Miyuki Inai and Toshiya Masuda
    • Journal Title

      Food Chemistry

      Volume: Vol.138 Pages: 1483-1492

    • DOI

      10.1016/j.foodchem.2012.11.073

    • Peer Reviewed
  • [Journal Article] ポリフェノールの酸化的変化, 生成物の構造とその機能2013

    • Author(s)
      増田 晃子, 増田 俊哉
    • Journal Title

      Foods and Food Ingredients Journal of Japan

      Volume: Vol.218, No.3 Pages: 258-265

    • URL

      http://www.ffcr.or.jp/zaidan/FFCRHOME.nsf/pages/ffij-j218(3)

  • [Journal Article] Curcumin : From Chemistry to Chemistry-Based Functions2013

    • Author(s)
      Akiko Masuda, Aya Fujimoto and Toshiya Masuda
    • Journal Title

      Current Pharmaceutical Design

      Volume: Vol.19, No.11 Pages: 2084-2092

    • DOI

      10.2174/138161213805289246

    • Peer Reviewed
  • [Journal Article] Chemical Interaction between Polyphenols and a Cysteinyl Thiol under Radical Oxidation Conditions2012

    • Author(s)
      Aya Fujimoto and Toshiya Masuda
    • Journal Title

      Journal of Agricultural and Food Chemistry

      Volume: Vol.60, No.20 Pages: 5142-5151

    • DOI

      10.1021/jf3008822

    • Peer Reviewed
  • [Journal Article] Radical Scavenging Activity of Spring Mountain Herbs in the Shikoku Mountain Area and Identification of Antiradical Constituents by Simple HPLC Detection and LC-MS Methods2012

    • Author(s)
      Toshiya Masuda, Inouchi Tomoko, Aya Fujimoto, Shingai Yoshimi, Inai Miyuki, Mitsuhiro Nakamura and Shoji Imai
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: Vol.76, No.4 Pages: 705-711

    • DOI

      10.1271/bbb.110837

    • Peer Reviewed
  • [Journal Article] Antioxidation Mechanism of Rosmarinic Acid, Identification of an Unstable Quinone Derivative by the Addition of Odorless Thiol2012

    • Author(s)
      Aya Fujimoto and Toshiya Masuda
    • Journal Title

      Food Chemistry

      Volume: Vol.132, No.2 Pages: 901-906

    • DOI

      10.1016/j.foodchem.2011.11.062

    • Peer Reviewed
  • [Journal Article] Structure and function of the oxidation products of polyphenols and identification of potent lipoxygenase inhibitors from fe-catalyzed oxidation of resveratrol2011

    • Author(s)
      Yoshimi Shingai, Aya Fujimoto, Mitsuhiro Nakamura and Toshiya Masuda
    • Journal Title

      Journal of Agricultural and Food Chemistry

      Volume: Vol.59, No.15 Pages: 8180-8186

    • DOI

      10.1021/jf202561p

    • Peer Reviewed
  • [Journal Article] 酸化されるポリフェノール, その安全性と機能2011

    • Author(s)
      藤本 彩, 増田 俊哉
    • Journal Title

      New Food Industry

      Volume: Vol.53, No.6 Pages: 21-27

    • URL

      http://www.newfoodindustry.com/information/cn11/cn17/pg259.html

  • [Presentation] フラボノイドとシステイン類の酸化的成分間反応物の構造と機能-XO阻害活性の増強2014

    • Author(s)
      三浦 ゆか理, 本田沙理, 稲井 美由紀, 増田 俊哉
    • Organizer
      2014年度日本農芸化学会大会
    • Place of Presentation
      明治大(神奈川県)
    • Year and Date
      2014-03-28
  • [Presentation] Effect of Polyphenols in the Presence of Cysteine on the Redox States of a Hemeprotein, Myoglobin2014

    • Author(s)
      Miyuki Inai, Yukari Miura, Sari Honda, Akiko Masuda, Toshiya Masuda
    • Organizer
      17th Biennial Meeting of Society for Free Radical Research International (SFRRI2014)
    • Place of Presentation
      KICC (Kyoto)
    • Year and Date
      2014-03-25
  • [Presentation] 脂質に対する各種システイン誘導体の抗酸化効果2013

    • Author(s)
      三浦 ゆか理, 稲井 美由紀, 増田 俊哉
    • Organizer
      日本農芸化学会日本ビタミン学会中四国支部合同大会
    • Place of Presentation
      県立広島大(広島県)
    • Year and Date
      2013-09-06
  • [Presentation] チオールによるフラボノイドの抗酸化性増強効果-成分間反応物からの解析-2013

    • Author(s)
      三浦 ゆか理, 稲井 美由紀, 増田 俊哉
    • Organizer
      2013年度日本農芸化学会大会
    • Place of Presentation
      東北大(宮城県)
    • Year and Date
      2013-03-25
  • [Presentation] 四国の民間健康茶の機能 ラジカル消去, α-グルコシダーゼ阻害, キサンチンオキシダーゼ阻害活性の評価(地域食資源の探索)2013

    • Author(s)
      増田 晃子, 井内 智子, 高橋 千鶴, 増田俊哉
    • Organizer
      日本農芸化学会中四国支部第35回講演会
    • Place of Presentation
      高知大(高知県)
    • Year and Date
      2013-01-26
  • [Presentation] ミオグロビンに対するポリフェノールのプロオキシダント作用とその制御2012

    • Author(s)
      稲井 美由紀, 藤本 彩, 増田 晃子, 山内聡, 増田 俊哉
    • Organizer
      2012年度日本農芸化学会中四国支部大会
    • Place of Presentation
      山口大(山口県)
    • Year and Date
      2012-09-22
  • [Presentation] 四国山地産春の山菜のラジカル消去機能とその機能性成分の特定2012

    • Author(s)
      藤本 彩, 増田 晃子, 井内 智子, 稲井 美由紀, 増田 俊哉
    • Organizer
      第59回日本食品科学工学会大会
    • Place of Presentation
      藤女大(北海道)
    • Year and Date
      2012-08-30
  • [Presentation] チオールによるカフェ酸, ジヒドロカフェ酸の抗酸化性増強効果-成分間反応物からの解析2012

    • Author(s)
      藤本 彩, 稲井 美由紀, 増田 俊哉
    • Organizer
      第65回日本酸化ストレス学会学術集会
    • Place of Presentation
      郷土文化会館(徳島県)
    • Year and Date
      2012-06-07
  • [Presentation] ポリフェノールとシステイン誘導体とのDPPH ラジカルによる反応2012

    • Author(s)
      藤本 彩, 増田 俊哉
    • Organizer
      日本農芸化学会2012年度大会
    • Place of Presentation
      京女大(京都府)
    • Year and Date
      2012-03-23
  • [Presentation] ポリフェノール酸化物の機能-α‐グルコシダーゼ, キサンチンオキシダーゼ阻害能と活性物質-2012

    • Author(s)
      新開 愛美, 藤本 彩, 中村 光裕, 増田俊哉
    • Organizer
      日本農芸化学会中四国支部第32回講演会
    • Place of Presentation
      鳥取大(鳥取県)
    • Year and Date
      2012-01-21
  • [Presentation] Polyphenol Oxidation, Structure and Function of The Product I. Tyrosinase Inhibitory Oxidation Products from Rosmarinic Acid2011

    • Author(s)
      Aya Fujimoto, Yoshimi Shingai, Mitsuhiro Nakamura, Tomomi Maekawa, Sone Yoshiaki and Toshiya Masuda
    • Organizer
      International Conference of Food Factor 2011
    • Place of Presentation
      TICC (Taiwan)
    • Year and Date
      2011-11-22
  • [Presentation] Polyphenol Oxidation, Structure and Function of the Product II. LC-MS Investigation of Lipoxygenase Inhibitory Products of Resveratrol Oxidation2011

    • Author(s)
      Yoshimi Shingai, Aya Fujimoto, Mitsuhiro Nakamura and Toshiya Masuda
    • Organizer
      International Conference of Food Factor 2011
    • Place of Presentation
      TICC (Taiwan)
    • Year and Date
      2011-11-22
  • [Presentation] ゴマ抗酸化フェノール・セサモール酸化物の構造と細胞毒性2011

    • Author(s)
      新開 愛美, 藤本 彩, 小山 保夫, 中村光裕, 前川 智美, 曽根 良昭, 増田 俊哉
    • Organizer
      第53回天然有機化合物討論会
    • Place of Presentation
      大阪国際センター(大阪府)
    • Year and Date
      2011-09-28
  • [Presentation] 反応生成物解析によるロスマリン酸の抗酸化反応機構の解明2011

    • Author(s)
      藤本 彩, 増田 俊哉
    • Organizer
      日本農芸化学会中四国支部第30回講演会
    • Place of Presentation
      岡山大(岡山県)
    • Year and Date
      2011-05-21
  • [Remarks] 酸化ストレス学会優秀演題賞(2012.6)(研究賞受賞)

  • [Remarks] 公益財団法人三木康楽会康楽賞研究の部(2012.1 および2014.1)(研究賞受賞)

  • [Patent(Industrial Property Rights)] 新規なナフトピラン化合物, 該化合物の製造方法およびその用途2013

    • Inventor(s)
      増田 俊哉
    • Industrial Property Rights Holder
      徳島大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      特願2013-78939
    • Filing Date
      2013-04-04

URL: 

Published: 2015-07-16  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi