2013 Fiscal Year Final Research Report
Dynamics of hydration water around biomolecules monitored by x-ray and neutron crystallography
| Project/Area Number |
23540478
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biophysics/Chemical physics
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Keywords | 水和構造 / 核酸 / タンパク質 / 構造転移 |
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| Research Abstract |
Mobile hydration water plays a part of essential role for functions of biomacromolecules. In order to analyze characteristics of hydration water, we carried out X-ray and neutron crystallographic analysis of structure transitions of protein and nucleotide crystals. Theoretical calculations were also performed. Concerning the hydration water around proteins, our results were consistent with the reports using neutron scattering, dielectric spectroscopic, and computer simulation methods. On the other hand, it was revealed that the hydration water around nucleic acids would have some different character compared with that of proteins.
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[Presentation] 生体分子関連物質結晶内の水和水の揺らぎと凍結2013
Author(s)
菅原洋子
Organizer
Workshop : CROSSroads of Users and J-PARC, 第8回「ナノ秒ダイナミクス系とその中性子散乱研究の将来」
Place of Presentation
いばらき量子ビーム研究センタ-(茨城県東海村)(依頼講演)
Year and Date
2013-11-11
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