2012 Fiscal Year Final Research Report
Development of direct catalytic asymmetric C-C bond-forming reactions based on thioamides and their applications to enantioselective synthesis of thtrapeutics
| Project/Area Number |
23590038
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Microbial Chemistry Research Foundation |
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Principal Investigator |
KUMAGAI Naoya 公益財団法人微生物化学研究会, 微生物化学研究所, 主任研究員 (40431887)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 不斉合成 / 不斉触媒 / チオアミド / 協奏機能触媒 / 医薬合成 / 原子効率 |
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| Research Abstract |
Several catalytic asymmetric reactions of synthetic value have been developed based on thioamide-based nucleophiles and electrophiles. These reactions were successfully utilized in short enantioselective synthesis of therapeutics.
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[Presentation] Naoya Kumagai2012
Author(s)
Soft Lewis Acid/Hard Bronsted Base Cooperative Asymmetric Catalysis
Organizer
University of Texas at El Paso
Place of Presentation
University of Texas at El Paso (USA)
Year and Date
2012-06-22
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[Presentation] Naoya Kumagai2012
Author(s)
Soft Lewis Acid/Hard Bronsted Base Cooperative Asymmetric Catalysis
Organizer
University of Texas at Austin
Place of Presentation
University of Texas at Austin (USA)
Year and Date
2012-06-21
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