2013 Fiscal Year Final Research Report
Visualization and cleavage of DNA using fluorescence and ultrasonication
| Project/Area Number |
23590043
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Physical pharmacy
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| Research Institution | Kyushu University |
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Principal Investigator |
NAKAZONO Manabu 九州大学, 薬学研究科(研究院), 助教 (90336074)
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| Co-Investigator(Renkei-kenkyūsha) |
NANBU Shinkoh 上智大学, 理工学部, 教授 (00249955)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 蛍光 / インドリルマレイミド / DNA |
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| Research Abstract |
Various unsymmetric indolylmaleimides were synthesized and the optical property
was clarified. Some indolylmaleimides have large Stokes shifts and fluorescence emission maxima
wavelengths of more than 550 nm. The fluorescence of indolylmaleimides was measured in the presence of double strand DNA. The fluorescence intensities of indolylmaleimides having N-methyl quinoline increased in the presence of double strand DNA.
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