2013 Fiscal Year Final Research Report
Comprehensive strategy for presymptomatic diagnosis of sudden death and heart
Project/Area Number |
23590813
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Public health/Health science
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Research Institution | Kitasato University |
Principal Investigator |
TOYO-OKA Teruhiko 北里大学, 医学(系)研究科(研究院), 客員教授 (00146151)
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Co-Investigator(Kenkyū-buntansha) |
IZUMI Tohru 北里大学, 名誉教授 (80143775)
KYO Shunei 東京大学, 医学部附属病院, 教授 (30153232)
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Project Period (FY) |
2011 – 2013
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Keywords | 心不全 / 突然死 / 遺伝子の網羅的解析 |
Research Abstract |
This study paid its attention to our country's own gene and aimed at the clinical development of the array for Japanese who analyzed both genomes of intramyocardial nucleus and mitochondria cyclopedically. The Japanese families were frequent for heart failure and sudden death, but, from the point where the metabolic views were not seen in at all, mt gene variation shows the hierarchical structure which is dominant for a nuclear gene. In other words, both genomes variation did not present heart failure independently, and it became clear to show the complicated condition of a patient by the interaction of both.
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Research Products
(27 results)
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[Presentation] An overview of the bioinformatics and a new concept of BWAS2012
Author(s)
Toyo-oka T, Toyo-oka L, Richter M, Tanaka T, Nakajima T, Kostin S, Izumi T, Ono M, Schaper J, Tokunaga K
Organizer
第17回、心臓病学会国際会議
Place of Presentation
Toronto, Canada(Medimond Press, 豊岡がA.Fleckenstein賞授与・記念講演, 抄録は2013年出版)
Year and Date
20120700
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