Establishment of objective index markers for the mental health problem in workers

2013 Fiscal Year Final Research Report

• Project/Area Number: 23590825
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Kansai University of Welfare Sciences
• Principal Investigator: KURATSUNE HIROHIKO 関西福祉科学大学, 健康福祉学部, 教授 (50195533)
• Co-Investigator(Kenkyū-buntansha): 平田 まり 関西福祉科学大学, 教授 (90173244) ; 大川 尚子 関西福祉科学大学, 教授 (70369685) ; 長見 まき子 関西福祉科学大学, 准教授 (10388663) ; 中富 康仁 大阪市立大学, 大学院医学, 研究科後期研究員 (90566184)
• Project Period (FY): 2011 – 2013
• Keywords: 健康診断 / メンタルヘルス障害

Research Abstract

To clarify the objective features of the fatigue state, we investigated subjective symptoms, autonomic nerve function, physical activities, and sleep parameters in 207 college students and 430 staff members of a school that had been affected by the Great East Japan Earthquake in A-city, and 304 staff members of a school in west Japan. College students study suggests that autonomic nerve function is related to the fatigue symptoms, physical activities, and sleep parameters. Furthermore, the study for the staff members of a school indicates that both members in A-city and west Japan have not only severe fatigue symptoms, but also sympathetic hyperactivity, low awake activity and increase counts of catnaps during waking hours.
These data suggests that autonomic nerve function is clearly related to the fatigue symptoms, physical activities, and sleep parameters, and that it is a possible to make a diagnostic algorithm for fatigue state by using these objective index markers.

Research Products

• [Journal Article] Neuro- inflammation in patients with chronic fatigue syndrome/myalgic encephalo- myelitis : a 11C-(R)-PK11195 positron emission tomography study (2014)
  • Author(s): Nakatomi Y, Mizuno K, Ishii A, Wada Y, Tanaka M, Tazawa S, Onoe K, Fukuda S, Kawabe J, Takahashi K, Kataoka Y, Shiomi S, Yamaguti K, Inaba M, Kuratsune H, Watanabe Y
  • Journal Title: Journal of Nuclear Medicine Volume: (in press)
• [Journal Article] 東日本大震災被災地域における教職員に対する健康評価 (2014)
  • Author(s): 大川尚子, 倉恒弘彦, 他
  • Journal Title: 日本疲労学会雑誌 Volume: (印刷中)
• [Journal Article] Autonomic Dysfunction in Chronic Fatigue Syndrome (2013)
  • Author(s): Yamaguti,K. Tajima S. and Kuratsune H
  • Journal Title: Advances in Neuroimmune Biology Volume: 4(4) Pages: 281-289
• [Journal Article] Autonomic Function is Associated With Health-Related Quality of Life in Patients With End-Stage Renal Disease : A Case-Control Study (2013)
  • Author(s): Fujii H, Koyama H, Fukuda S, Tokai H, Tajima S, Koizumi JI, Yamaguti K, Kuratsune H, Watanabe Y, Hirayama Y, Shoji T, Inaba M, Nishizawa Y
  • Journal Title: J Ren Nutr Volume: (pii : S1051-2276(13) 00004-6)
• [Journal Article] 大学生の疲労度と自律神経機能評価-保健室利用者と一般女子学生との比較- (2013)
  • Author(s): 大川尚子, 平田まり, 長見まき子, 野口法子, 藤原和美, 松村歌子, 柳本静子, 田島世貴, 小泉淳一, 倉恒弘彦
  • Journal Title: 日本疲労学会雑 Volume: 8(2) Pages: 60-65
• [Journal Article] Fatigue-related Problem Scale for better understanding of pathophysiology of chronic fatigue syndrome : discriminating from fibromyalgia and related pain (2012)
  • Author(s): Fukuda S., Kur atsune H., Kajimoto O., Watanabe Y
  • Journal Title: Advances in Neuroimmune Biology Volume: 3(3-4)
  • DOI: 10.3233/NIB-012906
• [Journal Article] Visible and near-infrared spectra collected from the thumbs of patients with chronic fatigue syndrome for diagnosis (2012)
  • Author(s): Sakudo A., Kur atsune H., Hakariya KatoY., Ikuta K
  • Journal Title: Clinica Chimica Acta Volume: 413(19-20) Pages: 1629-32
• [Journal Article] Changes in reaction time, coefficient of variance of reaction time, and autonomic nerve function in the mental fatigue state caused by long-term computerized Kraepelin test workload in healthy volunteers (2012)
  • Author(s): Kuratsune D, Tajima S, Koizumi J, Yamaguti K, Sasabe T, Mizuno K, Tanaka M, Okawa N, Mito H, Tsubone H, Watanabe Y, Inoue M, and Kur atsune H
  • Journal Title: World Journal of Neuroscience Volume: 2 Pages: 113-118
• [Journal Article] Autonomic nervous alterations associated with daily level of fatigue (2011)
  • Author(s): Tanaka M., Mizuno K., Yamaguti K., Kuratsune H., Fujii A., Baba H., Matsuda K., Nishimae A., Takesaka T., Watanabe Y
  • Journal Title: Behav Brain Funct Volume: 7 Pages: 46
  • URL: http://www.behavioralandbrainfunctions.com/content/7/1/46
• [Remarks]
  • URL: http://www.fuksi-kagk-u.ac.jp/guide/efforts/research/kuratsune/index.html