2013 Fiscal Year Final Research Report
Cytokine storms in severe influenza-related pneumonia
| Project/Area Number |
23591151
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Osaka University |
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Principal Investigator |
SEKI Masafumi 大阪大学, 医学部附属病院, 講師 (80432970)
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| Co-Investigator(Kenkyū-buntansha) |
TOMONO Kazunori 大阪大学, 医学部附属病院, 教授 (40202204)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 肺炎 / インフルエンザ / 好中球 / ＮＥＴｓ / 次世代シークエンサー |
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| Research Abstract |
In the basic research field, we analyzed the excessive immune responses, including apoptosis and NETs: neutrophil extracelluar traps, in both human pneuminia cases and mice models.
In clinical research field, NHCAP: the nurshing and healthcare-associated pneumonia, cases were analyzed, and published the paper about therapeutic regimen and infection control for aspiration pneumonia in elderly persons and nosocomial pneumonia due to drug resistant pathogens, including MRSA.
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