2013 Fiscal Year Final Research Report
Recovering process from language dysfunction caused by brain damage in children using magnetoencephalography
| Project/Area Number |
23591488
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TAKEUCHI Fumiya 北海道大学, 大学院保健科学研究院, 准教授 (30281835)
SAITOH Shinji 名古屋市立大学, 医学研究科, 教授 (00281824)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 言語機能 / 脳磁図 / 急性脳症 / 言語発達遅滞 / 非侵襲的評価 |
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| Research Abstract |
We investigated the process of recovering from language dysfunction in child patients with acute encephalitis or congenital language disability using magnetoencephalography (MEG). We invented a language stimulator for children and studied sequential progress of language function. Five patients enrolled our study and 3 patients have been studied more than once. We found alpha band oscillation depression in term of event related desynchronization at the language dominant hemisphere and the area has enlarged year by year. Our study demonstrated the mechanism of language development in children directly.
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[Journal Article] Publication criteria for evoked magnetic fields of the human brain : A proposal2012
Author(s)
Ozaki I, Shiraishi H, Kamada K, Kameyama S, Tsuyuguchi N, Yumoto M, Watanabe Y, Hirata M, Ishii R, Iguchi Y, Kimura T, Takino R, Hashimoto I
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Journal Title
Clin neurophysiol
Volume: 123
Pages: 2116-21
DOI
Peer Reviewed
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[Journal Article] Childhood-onset anti-MuSK antibody positive myasthenia gravis demonstrates a distinct clinical course2012
Author(s)
Takahashi Y, Sugiyama M, Ueda Y, Itoh T, Yagyu K, Shiraishi H, Ukeba-Terashita Y, Nakanishi M, Nagashima T, Imai T, Motomura M, Saitoh S
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Journal Title
Brain Dev
Volume: 34
Pages: 784-6
DOI
Peer Reviewed
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[Journal Article] PCDH19 mutation in Japanese females with epilepsy2012
Author(s)
Higurashi N, Shi X, Yasumoto S, Oguni H, Sakauchi M, Itomi K, Miyamoto A, Shiraishi H, Kato T, Makita Y, Hirose S
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Journal Title
Epilepsy Res
Volume: 99
Pages: 28-37
DOI
Peer Reviewed
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[Journal Article] Comparison of Three Methods for Localizing Interictal Epileptiform Discharges with Magnetoencephalography2011
Author(s)
Shiraishi H, Ahlfors SP, Stufflebeam SM, Knake S, Larsson PG, Hämäläinen MS, Takano K, Okajima M, Hatanaka K, Saitoh S, Dale AM, Halgren E
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Journal Title
J Clin Neurophysiol
Volume: 28
Pages: 431-40
DOI
Peer Reviewed
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[Presentation] Magnetoencephalography and Ethosuximide to identify atypical benign partial epilepsy : Rolandic-sylvian and thalamo-cortical epilepsy network2011
Author(s)
Shiraishi H, Haginoya K, Nakagawa E, Saitoh S, Kohsaka S, Kaneko Y, Sugai K, Uematsu M, Kakisaka Y, Nakasato N, Chan D, Hanaya R, Akiyama T, Otsubo H
Organizer
the 65th Annual Meeting of the American Epilepsy Society
Place of Presentation
Baltimore Convention Center(Baltimore, USA)
Year and Date
20111202-06
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