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2013 Fiscal Year Final Research Report

Diagnosis of cerebral arterial dissection using MRI

Research Project

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Project/Area Number 23591748
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionYamagata University

Principal Investigator

TAKAAKI Hosoya  山形大学, 医学部, 教授 (50143102)

Co-Investigator(Kenkyū-buntansha) ODA Atsuko  山形大学, 医学部, 助教 (10333965)
KANOTO Masafumi  山形大学, 医学部, 講師 (90400572)
TOYOGUCHI Yuki  山形大学, 医学部, 助教 (30466635)
Project Period (FY) 2011 – 2013
Keywords脳動脈解離 / MRI / 脳梗塞
Research Abstract

Although cerebral arterial dissection is recognized as one of the most important causes leading apoplexy of young people, it is difficult to diagnose correctly in acute phase. We developed a novel MRI technique, multislice motion-sensitized driven-equilibrium (MSDE) and used it for making diagnosis of cerebral arterial dissection.
We were able to diagnose 15 patients as cerebral arterial dissection in this study. Intramural hematoma, reliable finding of arterial dissection, was delineated in all 15 patients. In 11 patients who were examined in acute phase, the intramural hematoma was visualized in 10 patients (91%).
The intramural hematoma can be visualized even in acute phase using our novel MRI technique which suppress flow signal completely. Thus, we can make a diagnosis of cerebral arterial dissection unless the artery was occluded. Our noninvasive diagnostic technique enables us to analyze it more precisely and will also contribute to development of an effective treatment.

  • Research Products

    (4 results)

All 2014 2012

All Presentation (4 results)

  • [Presentation] 急性期脳動脈解離の画像診断2014

    • Author(s)
      豊口裕樹
    • Organizer
      第37回日本脳神経CI学会総会
    • Place of Presentation
      大宮ソニックシティ(埼玉県)
    • Year and Date
      2014-02-28
  • [Presentation] 急性期脳動脈解離における壁内血腫の画像所見―3D T1強調black- blood imagingを用いた検討2012

    • Author(s)
      小田敦子
    • Organizer
      第35回東北脳血管障害研究会
    • Place of Presentation
      江陽グランドホテル(宮城県)
    • Year and Date
      2012-12-01
  • [Presentation] MR findings of intramural hematoma in acute phase of cerebral artery dissection using 3D T1-weighted black-blood imaging2012

    • Author(s)
      小田敦子
    • Organizer
      第36回ヨーロッパ神経放射線学会
    • Place of Presentation
      Edinburgh International Conference Centre(英国)
    • Year and Date
      2012-09-21
  • [Presentation] 急性期脳動脈解離における壁内血腫の画像所見―3D T1強調black- blood imagingを用いた検討2012

    • Author(s)
      小田敦子
    • Organizer
      第71回日本放射線医学学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2012-04-14

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Published: 2015-07-16  

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