2013 Fiscal Year Final Research Report
Influence of radiation dose on detection of early CT sign of acute cerebral infarction and aneurysms
| Project/Area Number |
23591814
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Nagoya University |
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Principal Investigator |
IMAI Kuniharu 名古屋大学, 医学(系)研究科(研究院), 教授 (20335053)
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| Co-Investigator(Kenkyū-buntansha) |
IKEDA Mitsuru 名古屋大学, 大学院医学系研究科, 教授 (50184437)
KAWAURA Chiyo 名古屋大学, 大学院医学系研究科, 助教 (60324422)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 脳卒中 / CT画像 / 水晶体線量 / 鮮鋭度 / 輪郭検出能 / コントラスト分解能 / 単位被ばく線量当たりの情報量 / 撮像条件 |
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| Research Abstract |
The purpose of this study is to propose the optimal exposure parameters in brain CT examination for stroke. We have designed two kinds of the brain phantoms and subcontracted the phantom manufacture to R-TEC Co. Ltd and Techno-rad Co.Ltd: one is composed of simulated brain parenchyma, intracranial arteries with various intracranial aneurysms, and skull bone, and the other is composed of simulated brain parenchyma with ischemic damage and complete infarction and skull bone. These head phantoms were scanned using a 64-multidetector CT scanner with various exposure parameters and use of various reconstruction techniques. These results were summarized as follows; (1) Lens dose increased with tube voltage and current. (2) The detectability of aneurysms was improved by reconstructing CT images using a model based iterative reconstruction algorism. (3) Dual energy scanning technique yielded the improvement of the detectability of the hypodensities corresponding to early ischemic brain damage.
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