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2013 Fiscal Year Final Research Report

Development of intra-abdominal space modulated radiotherapy

Research Project

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Project/Area Number 23591840
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionKobe University

Principal Investigator

MURAOKA OSAMU  神戸大学, 医学(系)研究科(研究院), 研究員 (20283765)

Co-Investigator(Kenkyū-buntansha) FUKUMOTO Takumi  神戸大学, 医学(系)研究科(研究院), 准教授 (70379402)
YOSHIDA Kenji  神戸大学, 医学部附属病院, 特命講師 (80351906)
Project Period (FY) 2011 – 2013
Keywords放射線治療 / スペーサー
Research Abstract

Originally invented nonwoven fabric polyglycolic acid (PGA) spacer was tested by physical experiment and animal experiments. The PGA spacer exhibits excellent properties related to bio-absorbability, bio-compatibility, and thickness retention. Adhesion of the PGA spacer was minimum and blood test indicated that there was no inflammatory reaction. The retension of the PGA spacer depends upon its density. These findings should be more intensively investigated for the clinical application. The PGA spacer will be a useful method for particle therapy without damaging adjacent organs.

  • Research Products

    (28 results)

All 2014 2013 2012

All Journal Article (10 results) (of which Peer Reviewed: 10 results) Presentation (18 results)

  • [Journal Article] Effect of heterogeneity correction on dosimetric parameters of radiotherapy planning for thoracic esophageal cancer2014

    • Author(s)
      Nakayama M, Yoshida K, Nishimura H, Miyawaki D, Uehara K, Okamoto Y, Okayama T, Sasaki R.
    • Journal Title

      Med Dosim

      Volume: 39(1) Pages: 31-3

    • DOI

      10.1016/j.meddos.2013.09.001

    • Peer Reviewed
  • [Journal Article] Prognostic Value of FDG PET Imaging in Patients with Laryngeal Cancer2014

    • Author(s)
      Kitajima K, Suenaga Y, Kanda T, Miyawaki D, Yoshida K, Ejima Y, Sasaki R, Komatsu H, Saito M, Otsuki N, Nibu K, Kiyota N, Minamikawa T, Sugimura K.
    • Journal Title

      PLoS One

      Volume: 9(5) Pages: e96999

    • DOI

      10.1371/journal.pone.0096999.eCollection2014

    • Peer Reviewed
  • [Journal Article] Factors affecting survival after resection of intrahepatic cholangio -carcinoma2014

    • Author(s)
      Murakami S, Ajiki T, Okazaki T, Ueno K, Kido M, Matsumoto I, Fukumoto T, Ku Y.
    • Journal Title

      Surg Today

      Volume: (Epub ahead of print)

    • Peer Reviewed
  • [Journal Article] Contrast-enhanced intraoperative ultrasonic cholangio -graphy for real-time biliary navigation in hepatobiliary surgery2014

    • Author(s)
      Urade T, Fukumoto T, Tanaka M, Kido M, Takebe A, Kuramitsu K, Chuma M, Matsumoto I, Ajiki T, Ku Y.
    • Journal Title

      J Am Coll Surg

      Volume: 218(2) Pages: e43-50

    • DOI

      10.1016/j.jamcollsurg.2013.10.003

    • Peer Reviewed
  • [Journal Article] Assessment of ISGLS definition of posthepatectomy liver failure and its effect on outcome in patients with hepatocellular carcinoma2014

    • Author(s)
      Fukushima K, Fukumoto T, Kuramitsu K, Kido M, Takebe A, Tanaka M, Itoh T, Ku Y.
    • Journal Title

      J Gastrointest Surg

      Volume: 18(4) Pages: 729-36

    • DOI

      10.1007/s11605-013-2423-y

    • Peer Reviewed
  • [Journal Article] Long-term outcomes and prognostic factors with reductive hepatectomy and sequential percutaneous isolated hepatic perfusion for multiple bilobar hepatocellular carcinoma2014

    • Author(s)
      Fukumoto T, Tominaga M, Kido M, Takebe A, Tanaka M, Kuramitsu K, Matsumoto I, Ajiki T, Ku Y.
    • Journal Title

      Ann Surg Oncol

      Volume: 21(3) Pages: 971-8

    • DOI

      10.1245/s10434-013-3305-y

    • Peer Reviewed
  • [Journal Article] Gallbladder bed pocket score as a preoperative measure for assessing the difficulty of laparoscopic cholecystectomy2013

    • Author(s)
      Shinozaki K, Ajiki T, Okazaki T, Ueno K, Matsumoto T, Ohtsubo I, Murakami S, Yoshida Y, Matsumoto I, Fukumoto T, Sugimoto T, Ohno M, Ku Y.
    • Journal Title

      Asian J Endosc Surg

      Volume: 6(4) Pages: 285-91

    • DOI

      10.1111/ases.12051

    • Peer Reviewed
  • [Journal Article] Curative resection of hilar cholangiocarcinoma in a 25-year-old woman : report of a case2013

    • Author(s)
      Murakami S, Ajiki T, Ueno K, Sawa H, Tsuchida S, Otsubo I, Yoshida Y, Shinozaki K, Okazaki T, Matsumoto I, Fukumoto T, Ku Y.
    • Journal Title

      Surg Today

      Volume: (Epub ahead of print)

    • Peer Reviewed
  • [Journal Article] 18-Fluorodeoxyglucose positron emission tomography does not aid in diagnosis of pancreatic ductal adenocarcinoma2013

    • Author(s)
      Matsumoto I, Shirakawa S, Shinzeki M, Asari S, Goto T, Ajiki T, Fukumoto T, Kitajima K, Ku Y.
    • Journal Title

      Clin Gastroenterol Hepatol

      Volume: 11(6) Pages: 712-8

    • DOI

      10.1016/j.cgh.2012.12.033

    • Peer Reviewed
  • [Journal Article] Radiotherapy for stage I or II hypopharyngeal carcinoma2012

    • Author(s)
      Nishimura H, Sasaki R, Yoshida K, Miyawaki D, Okamoto Y, Kiyota N, Saito M, Otsuki N, Nibu K.
    • Journal Title

      J Radiat Res

      Volume: 53(6) Pages: 892-9

    • DOI

      10.1093/jrr/rrs044

    • Peer Reviewed
  • [Presentation] Functional outcomes of the facial nerve after post operative radiation therapy for high risk parotid gland malignancies underwent radical surgery with facial nerve resection and reconstructive surger2013

    • Author(s)
      O Muraoka, H Nishimura, D Miyawaki, K Yoshida, Y Ejima, Y Okamoto, K Hashikawa, N Otsuki, K Nibu, R Sasaki, y
    • Organizer
      55th Annual meeting ASTRO
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      20130922-25
  • [Presentation] Efficacy of Surgically Implanted Flexible Spacer in Particle Therapy : A novel strategy Making Temporal Space between Tumor and Adjacent Organs2013

    • Author(s)
      H Akasaka, R Sasaki, T Fukumoto, N Mukumoto, M Nakayama, H Nishimura, K Yoshida, D Miyawaki, S Yamada, M Murakami
    • Organizer
      55th Annual meeting ASTRO
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      20130922-25
  • [Presentation] 耳下腺癌/顎下腺癌術後症例に対する放射線治療の検討2013

    • Author(s)
      村岡修、宮脇大輔、西村英輝、吉田賢史、江島泰生、大月直樹、森本浩一、山下大介、丹生健一、岡本欣晃、佐々木良平
    • Organizer
      第37回日本頭頸部癌学会
    • Place of Presentation
      東京
    • Year and Date
      20130613-14
  • [Presentation] 顎下腺癌に対する術後放射線療法の検討2012

    • Author(s)
      村岡修、宮脇大輔、西村英輝、吉田賢史、原田文、ノルシャズリナ、大月直樹、丹生健一、岡本欣晃、佐々木良平
    • Organizer
      日本放射線腫瘍学会第25回学術大会
    • Place of Presentation
      東京
    • Year and Date
      20121123-25
  • [Presentation] 当院における中咽頭扁平上皮癌に対する放射線治療成績2012

    • Author(s)
      宮脇大輔、吉田賢史、西村英輝、原田文、村岡修、ノルシャズリナ、清田尚臣、大月直樹、丹生健一、佐々木良平
    • Organizer
      日本放射線腫瘍学会第25回学術大会
    • Place of Presentation
      東京
    • Year and Date
      20121100
  • [Presentation] Postoperative radiotherapy for the malignant tumors of the parotid gland2012

    • Author(s)
      O Muraoka, D Miyawaki, H Nishimura, K Yoshida, A Harada, NS Sulaiman, N Otsuki, K Nibu, Y Okamoto, R Sasaki
    • Organizer
      The 6th S.Takahashi Memorial Symposium & The 6th Japan-US Cancer Therapy International Joint Symposium
    • Place of Presentation
      Hiroshima
    • Year and Date
      20120719-21
  • [Presentation] Surgically Implanted Flexible Spacer in Particle Therapy : Making Temporal Space between Tumor and Adjacent Organs!2012

    • Author(s)
      R Sasaki, H Akasaka, T Fukumoto, N Mukumoto, H Nishimura, K Yoshida, D Miyawaki, S Yamada, M Murakami
    • Organizer
      The 6th S.Takahashi Memorial Symposium & The 6th Japan-US Cancer Therapy International Joint Symposium
    • Place of Presentation
      Hiroshima
    • Year and Date
      20120719-21
  • [Presentation] A Novel Radiosensitizor, Monogalactosyl -diacyglycerol(MDGD)from Spinach, Enhanced the Cytotoxicity of Radiotherapy to Pancreatic Cancer2012

    • Author(s)
      H Akasaka, R Sasaki, I Takayama, M Nakahana, NELLY, M Nakayama, D Miyawaki, K Yoshida, H Nishimura, Y Mizushina
    • Organizer
      The 6th S.Takahashi Memorial Symposium & The 6th Japan-US Cancer Therapy International Joint Symposium
    • Place of Presentation
      Hiroshima
    • Year and Date
      20120719-21
  • [Presentation] Therapeutic Strategies aimed at Laryngeal Preservation of T1-T3N0 Glottic Laryngeal cancer2012

    • Author(s)
      A Harada, R Sasaki, NS Sulaiman, O Muraoka, D Miyawaki, K Yoshida, H Nishimura, M Saito, N Otsuki, K Nibu
    • Organizer
      The 6th Japan-US Cancer Therapy International Joint Symposium
    • Place of Presentation
      Hiroshima
    • Year and Date
      20120719-21
  • [Presentation] Chemoradiotherapy in Patients with Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma2012

    • Author(s)
      H Nishimura, K Yoshida, D Miyawaki, M Oda, T Okuno, N Kiyota, A Harada, O Muraoka, NS Sulaiman, R Sasaki
    • Organizer
      The 6th Japan-US Cancer Therapy International Joint Symposium
    • Place of Presentation
      Hiroshima
    • Year and Date
      20120719-21
  • [Presentation] T1-T3NO声門癌の喉頭温存を目指した治療方針の検討2012

    • Author(s)
      原田文、宮脇大輔、吉田賢史、西村英輝、村岡修、ノルシャズリナ、斉藤幹、大月直樹、丹生健一、佐々木良平
    • Organizer
      第36回日本頭頸部癌学会
    • Place of Presentation
      松江市
    • Year and Date
      20120606-07
  • [Presentation] 当院における中咽頭扁平上皮癌に対する放射線治療成績2012

    • Author(s)
      宮脇大輔、西村英輝、吉田賢史、原田文、村岡修、ノルシャズリナ、清田尚臣、斉藤幹、大月直樹、丹生健一、佐々木良平
    • Organizer
      第36回日本頭頸部癌学会
    • Place of Presentation
      松江市
    • Year and Date
      20120606-07
  • [Presentation] 鼻腔悪性黒色腫に対する大線量小分割法放射線治療の経験2012

    • Author(s)
      ノルシャズリナ、吉田賢史、西村英輝、宮脇大輔、原田文、村岡修、岡本欣晃、土井清司、大月直樹、丹生健一、佐々木良平
    • Organizer
      第36回日本頭頸部癌学会
    • Place of Presentation
      松江
    • Year and Date
      20120606-07
  • [Presentation] 高齢頭頸部癌患者に対する放射線治療の経験-10年間の検討-2012

    • Author(s)
      吉田賢史、西村英輝、宮脇大輔、村岡修、原田文、ノルシャズリナ、斉藤幹、大月直樹、丹生健一、佐々木良平
    • Organizer
      第36回日本頭頸部癌学会
    • Place of Presentation
      松江市
    • Year and Date
      20120606-07
  • [Presentation] 顎下腺癌に対する放射線療法の経験2012

    • Author(s)
      村岡修、宮脇大輔、西村英輝、吉田賢史、原田文、ノルシャズリナ、大月直樹、柴田智久、米澤宏一郎、森本浩一、山下大介、丹生健一、岡本欣晃、佐々木良平
    • Organizer
      第36回日本頭頸部癌学会
    • Place of Presentation
      松江市
    • Year and Date
      20120606-07
  • [Presentation] T1-T3NO声門癌の喉頭温存を目指した治療方針の検討2012

    • Author(s)
      原田文、佐々木良平、西村英輝、吉田賢史、宮脇大輔、村岡修、ノルシャズリナ、丹生健一、大月直樹、斉藤幹
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      20120412-15
  • [Presentation] 耳下腺癌術後症例に対する放射線療法の経験2012

    • Author(s)
      村岡修、宮脇大輔、西村英輝、吉田賢史、原田文、ノルシャズリナ、佐々木良平、大月直樹、丹生健一、岡本欣晃
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      20120412-15
  • [Presentation] 脳幹部Gliomaに対する放射線治療の経験2012

    • Author(s)
      吉田賢史、西村英輝、宮脇大輔、原田文、村岡修、ノルシャズリナ、上原和之、早川晶、篠山隆司、佐々木良平
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      20120412-15

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Published: 2015-07-16  

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