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2013 Fiscal Year Final Research Report

High speed imaging of the vocal folds and phonatory function tests to determine voice therapy regimens for patients with severe voice disorders.

Research Project

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Project/Area Number 23592540
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Otorhinolaryngology
Research InstitutionNihon University

Principal Investigator

MAKIYAMA KIYOSHI  日本大学, 医学部, 教授 (00139172)

Co-Investigator(Kenkyū-buntansha) NIIMI Seiji  国際医療福祉大学, 保健学部, 教授 (00010273)
TSUNODA Koichi  独立行政法人国立病院機構東京医療センター 臨床研究センター, 人工臓器機器開発部, 部長 (30197751)
HIRAI Ryoji  日本大学, 医学部, 助教 (70409027)
Co-Investigator(Renkei-kenkyūsha) MATSUZAKI Hiroumi  日本大学, 医学部, 助教 (00451328)
TAKANE Tomoyuki  日本大学, 医学部, 助手 (80599035)
Project Period (FY) 2011 – 2013
Keywords発声機能検査 / 高速デジタル撮影 / 位相差 / 音声障害
Research Abstract

This study examined tests, treatment selection, and outcomes for 695 new patients examined at our voice clinic between July 2011 and November 2013. All patients underwent fiberoptic laryngoscopy, laryngeal stroboscopy, phonatory function tests, and acoustic analysis. High speed imaging of the vocal folds was conducted 443 times in 204 patients. Patients were classified into some types based on these test results. Additional parameters, including glottis morphology, vibration patterns, aerodynamic phonatory function, and hoarseness characteristics during phonation, were used to investigate the suitability of individual or joint application of voice therapy and surgical treatment. The present findings indicate that treatment should be selected based on these inspections, except for cases involving tumors and similar disorders. Treatment selection was also affected by patients' appointment attendance status and their motivation toward improving hoarseness.

  • Research Products

    (34 results)

All 2014 2013 2012 2011

All Journal Article (13 results) (of which Peer Reviewed: 10 results) Presentation (19 results) Book (2 results)

  • [Journal Article] Assessment of Human Papilloma Virus Infection in Adult Laryngeal Papilloma Using a Screening Test2013

    • Author(s)
      Makiyama K, Hirai R, Matsuzaki H, Ikeda M
    • Journal Title

      J Voice

      Volume: 27(2) Pages: 230-235

    • DOI

      10.1016/j.jvoice.2012.10.014

    • Peer Reviewed
  • [Journal Article] Pharyngeal squamous cell papilloma in adult Japanese2012

    • Author(s)
      Hirai R, Makiyama K
    • Journal Title

      Eur Arch Otorhinolaryngol

      Volume: 269 Pages: 2271-2276

    • DOI

      10.1007/s00405-011-1908-0

    • Peer Reviewed
  • [Journal Article] Surgical improvement of speech disorder caused by amyotrophic lateral sclerosis2012

    • Author(s)
      Niimi S(9/9人)et al
    • Journal Title

      Tohoku J Exp Med

      Volume: 228(4) Pages: 371-6

    • Peer Reviewed
  • [Journal Article] 嗄声の聴覚心理的評価2012

    • Author(s)
      牧山清
    • Journal Title

      日耳鼻会報

      Volume: 115 Pages: 930-931

  • [Journal Article] 音声機能検査2012

    • Author(s)
      牧山清,平井良治
    • Journal Title

      JOHNS

      Volume: 28(6) Pages: 915-921

  • [Journal Article] Brain Activity in aphonia after a coughing episode : Different brain activity in healthy whispering and pathological condition2012

    • Author(s)
      Tsunoda K, Sekimoto S, Baer T
    • Journal Title

      J Voice

      Volume: 26(5) Pages: 668.e11-3

    • DOI

      10.1016/j.jvoice.2011.11.004

    • Peer Reviewed
  • [Journal Article] 声帯ポリープの臨床統計2012

    • Author(s)
      新美成二(7/8人)et al
    • Journal Title

      日気食会報有

      Volume: 63(4) Pages: 291-298

    • Peer Reviewed
  • [Journal Article] 職業歌手にみられる音声障害への対処2012

    • Author(s)
      新美成二(6/7人)et al
    • Journal Title

      音声言語

      Volume: 53(2) Pages: 153-157

    • Peer Reviewed
  • [Journal Article] 高齢化社会と耳鼻咽喉科,老人性疾患の予防と対策-声帯萎縮2012

    • Author(s)
      角田晃一
    • Journal Title

      JOHNS

      Volume: 28(9) Pages: 1371-1375

    • Peer Reviewed
  • [Journal Article] 声帯内注入術何をどこに-適応と限界-2012

    • Author(s)
      角田晃一
    • Journal Title

      音声言語医学

      Volume: 53(4) Pages: 276-280

    • Peer Reviewed
  • [Journal Article] 声帯高速撮影検査-アテロコラーゲン注入術への臨床応用-2011

    • Author(s)
      牧山清,高根智之,平井良治,岸博行,児玉ひとみ
    • Journal Title

      喉頭

      Volume: 23 Pages: 49-58

    • Peer Reviewed
  • [Journal Article] Vocal acoustic characteristics of patients with Parkinson's disease2011

    • Author(s)
      Tanaka Y, Nishio M, Niimi S
    • Journal Title

      Folia Phoniatr Logop

      Volume: 63(5) Pages: 223-30

    • DOI

      10.1159/000322059

    • Peer Reviewed
  • [Journal Article] 音声のリハビリテーション-音声リハビリテーションについて2011

    • Author(s)
      新美成二
    • Journal Title

      気食会報

      Volume: 62(5) Pages: 433-439

  • [Presentation] 声がれの検査と治療2014

    • Author(s)
      牧山清
    • Organizer
      駿河台日本大学病院公開講座
    • Place of Presentation
      駿河台日本大学病院(特別講演)
    • Year and Date
      2014-01-25
  • [Presentation] 発声機能と加齢2013

    • Author(s)
      牧山清
    • Organizer
      第65回日本気管食道科学会
    • Place of Presentation
      品川プリンスホテル(シンポジウム:高齢化社会と気管食道科)
    • Year and Date
      2013-10-31
  • [Presentation] 喉頭ストロボ検査と高速デジタル撮影検査2013

    • Author(s)
      牧山清,高根智之
    • Organizer
      第65回日本気管食道科学会
    • Place of Presentation
      品川プリンスホテル(セミナー:声帯振動検査)
    • Year and Date
      2013-10-31
  • [Presentation] 音声機能検査の基礎・評価2013

    • Author(s)
      牧山清
    • Organizer
      第58回日本音声言語医学会
    • Place of Presentation
      高知県立県民文化ホール(セミナー:音声障害の診断から治療)
    • Year and Date
      2013-10-19
  • [Presentation] YAG Laser-Application to Laryngeal Microsurgery2013

    • Author(s)
      K Makiyama, H Matsuzaki, R Hirai
    • Organizer
      AAO-HNS
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2013-09-30
  • [Presentation] Is there any correlation between aerodynamic and vocal cord vibration parameters?2013

    • Author(s)
      H Matsuzaki, K Makiyama, T Takane
    • Organizer
      AAO-HNS
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2013-09-30
  • [Presentation] 嗄声疾患の診断治療-先端的検査法と独創的治療-2013

    • Author(s)
      牧山清
    • Organizer
      日耳鼻広島県研修会
    • Place of Presentation
      広島グランビアホテル(特別講演)
    • Year and Date
      2013-07-18
  • [Presentation] 喉頭疾患における先端的診断治療2013

    • Author(s)
      牧山清
    • Organizer
      Dr to Dr Meeting in文京
    • Place of Presentation
      東京ドームホテル(特別講演)
    • Year and Date
      2013-01-17
  • [Presentation] Yag laser-application to laryngeal tumor2012

    • Author(s)
      K Makiyama, R Hirai, T Takane
    • Organizer
      14th APALMS
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2012-11-24
  • [Presentation] 嗄声の診断と治療2012

    • Author(s)
      牧山清
    • Organizer
      第27回城北・埼玉南部耳鼻咽喉科学術集会
    • Place of Presentation
      ホテルメトロポリタン(特別講演)
    • Year and Date
      2012-10-25
  • [Presentation] Yag Laser-Application to laryngomicrosurgery2012

    • Author(s)
      K Makiyama, R Hirai, T Takane
    • Organizer
      17th WCB&WCBE
    • Place of Presentation
      Cleveland, USA
    • Year and Date
      2012-06-16
  • [Presentation] Phase defference by high-speed imaging of vocal folds in cases without phonetic disorder2012

    • Author(s)
      T Takane, K Makiyama, R Hirai
    • Organizer
      17th WCB&WCBE
    • Place of Presentation
      Cleveland, USA
    • Year and Date
      2012-06-16
  • [Presentation] A study of preoperative prediction of a difficult case for the direct laryngoscope to expose the larynx2012

    • Author(s)
      R Hirai, K Makiyama, T Takane
    • Organizer
      17th WCB&WCBE
    • Place of Presentation
      Cleveland, USA
    • Year and Date
      2012-06-16
  • [Presentation] 音声障害疾患の診断と治療2012

    • Author(s)
      牧山清
    • Organizer
      蕨戸田医師会講演会
    • Place of Presentation
      蕨戸田医師会館(特別講演)
    • Year and Date
      2012-03-14
  • [Presentation] HPV in pharyngeal papilloma2011

    • Author(s)
      R Hirai, K Makiyama, T Takane
    • Organizer
      11^<th> Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2011-12-08
  • [Presentation] 声帯内アテロコラーゲン注入術の適応と限界2011

    • Author(s)
      牧山清
    • Organizer
      第56回日本音声言語医学会
    • Place of Presentation
      ホテルグランドヒル市ヶ谷(シンポジウム:声帯内注入術-適応と限界)
    • Year and Date
      2011-10-06
  • [Presentation] 音声障害疾患の検査と治療2011

    • Author(s)
      牧山清
    • Organizer
      静岡県耳鼻咽喉科医会講演会
    • Place of Presentation
      ホテルアソシア静岡(特別講演)
    • Year and Date
      2011-06-14
  • [Presentation] 声帯高速撮影検査-アテロコラーゲン注入術への臨床応用-2011

    • Author(s)
      牧山清
    • Organizer
      第23回日本喉頭科学会
    • Place of Presentation
      旭川グランドホテル(シンポジウム:新しい喉頭麻痺治療へのtranslational research)
    • Year and Date
      2011-04-21
  • [Presentation] 嗄声の診断と治療2011

    • Author(s)
      牧山清
    • Organizer
      小石川医師会講演会
    • Place of Presentation
      小石川医師会館(特別講演)
    • Year and Date
      2011-02-25
  • [Book] Current Issues in Voice Assessment and Intervention. International Perspectives On Voice Disorders2013

    • Author(s)
      Koichi Tsunoda
    • Total Pages
      68-82
    • Publisher
      Edwin Yiu E, (Bristl UK)
  • [Book] 声帯麻痺の診断に際しての留意点、のどの異常とプライマリケア2013

    • Author(s)
      牧山清,平井良治
    • Total Pages
      182-187

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Published: 2015-07-16   Modified: 2018-02-02  

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