Translumenal Endoscopic Esophageal Anastomosis for Long-Gap Esophageal Atresia (Type A)

2014 Fiscal Year Final Research Report

• Project/Area Number: 23592626
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Pediatric surgery
• Research Institution: Saitama Medical University (2012-2014); The University of Tokyo (2011)
• Principal Investigator: TERAWAKI Kan 埼玉医科大学, 医学部, 講師 (00372384)
• Co-Investigator(Kenkyū-buntansha): TADASHI Iwanaka 東京大学, 医学部附属病院, 教授 (90193755)
• Co-Investigator(Renkei-kenkyūsha): TETSUYA Ishimaru 東京大学, 医学部附属病院, 助教 (00633629)
• Project Period (FY): 2011-04-28 – 2015-03-31
• Keywords: 小児外科 / 新生児外科 / 低侵襲手術 / NOTES / 術式開発 / 食道閉鎖症

Outline of Final Research Achievements

The aim of this study was to develop a novel procedure for esophageal anastomosis using NOTES (Natural Orifice Translumenal Endoscopic Surgery) approach.
We developed new devices, an expandable stent and a ligating device. The newly developed procedure using those devices for anastomosis is as follows, a silicone elastic band, which was released from the ligating device located at the upper esophagus, and a custom-made expandable stent, which was expanded by the balloon catheter in the lower esophagus, tightened the upper and lower esophageal walls.
An ex vivo feasibility study was performed in porcine models. Endoscopic visualization revealed that all steps in this procedure were technically successful. The median time needed to perform this procedure was 24 (range, 19-25) minutes. Patency of the anastomosis was confirmed in all cases.

Free Research Field

小児外科