Reduction system of radiation mucositis on radiotherapy for oral cancer

2013 Fiscal Year Final Research Report

• Project/Area Number: 23592763
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Pathobiological dentistry/Dental radiology
• Research Institution: Osaka University
• Principal Investigator: FURUKAWA Souhei 大阪大学, 歯学研究科(研究院), 教授 (80173524)
• Co-Investigator(Kenkyū-buntansha): MURAKAMI Shumei 大阪大学, 歯学研究科, 准教授 (00263301) ; KAKIMOTO Naoya 大阪大学, 歯学研究科, 講師 (50324794) ; UCHIYAMA Yuka 大阪大学, 歯学研究科, 助教 (80322171)
• Project Period (FY): 2011 – 2013
• Keywords: 放射線治療 / 防護装置 / MRI

Research Abstract

The aim of this study was to reduce the radiation mucositis on the radiotherapy for the oral cancers. First of all, we invented a new scoring system using the photo taken with an intra-oral camera and the MR image using IDEAL method.
Then, we invented a new appliance of radiation shield, which was set in the mouth. The materials of the new appliance were the lead (Pb) covered with the plastics. After the impression of the patient teeth, we made a plaster model. Using the plaster model we made the new appliance according to the method of making the denture.
Until now we have applied this new appliance to 12 patients and evaluated the radiation mucositis using the new scoring system above. And, it was suggested that the new appliance could reduce the radiation mucositis.

Research Products

• [Journal Article] Comparison of the T2 Relaxation Time of the Temporomandibular Joint Articular Disk between Patients with Temporomandibular Disorders and Asymptomatic Volunteers (2014)
  • Author(s): Kakimoto N, Shimamoto H, Chindasombatjaroen J, Tsujimoto T, Tomita S, Hasegawa Y, Murakami S, Furukawa S
  • Journal Title: AJNR Am J Neuroradiol Volume: (in press)
• [Journal Article] Evaluation of imaging performance of megavoltage cone-beam CT over an extended period (2014)
  • Author(s): Sumida I, Yamaguchi H, Kizaki H, Yamada Y, Koizumi M, Yoshioka Y, Ogawa K, Kakimoto N, Murakami S, Furukawa S
  • Journal Title: J Radiat Res Volume: 55(1) Pages: 191-9
• [Journal Article] Temporomandibular joints in patients with rheumatoid arthritis using magnetic resonance imaging (2013)
  • Author(s): Uchiyama Y, Murakami S, Furukawa S
  • Journal Title: Clin Rheumatol Volume: 32(11) Pages: 1613-8
• [Journal Article] Contrast-enhanced multidetector computerized tomography for odontogenic cysts and cystic-appearing tumors of the jaws : is it useful? (2013)
  • Author(s): Kakimoto N, Chindasombatjaroen J, Tomita S, Shimamoto H, Uchiyama Y, Hasegawa Y, Kishino M, Murakami S, Furukawa S
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Volume: 115(1) Pages: 104-13
• [Journal Article] CT and MR imaging features of a case of calcifying epithelial odontogenic tumor (2012)
  • Author(s): Uchiyama Y, Murakami S, Kishino M, Furukawa S
  • Journal Title: JBR-BTR Volume: 95(5) Pages: 315-9
• [Journal Article] Dose reduction trial from 60 Gy in 10 fractions to 54 Gy in 9 fractions schedule in high-dose-rate interstitial brachytherapy for early oral tongue cancer (2012)
  • Author(s): Akiyama H, Yoshida K, Shimizutani K, Yamazaki H, Koizumi M, Yoshioka Y, Kakimoto N, Murakami S, Furukawa S, Ogawa K
  • Journal Title: J Radiat Res Volume: 53(5) Pages: 722-6
• [Journal Article] Perineural spread of adenoid cystic carcinoma in the oral and maxillofacial regions : evaluation with contrast-enhanced CT and MRI (2012)
  • Author(s): Shimamoto H, Chindasombatjaroen J, Kakimoto N, Kishino M, Murakami S, Furukawa S
  • Journal Title: Dentomaxillofac Radiol Volume: 41(2) Pages: 143-51
• [Journal Article] Electron beam radiotherapy for tongue cancer using an intra-oral cone (2012)
  • Author(s): Kakimoto N, Murakami S, Nakatani A, Yoshioka Y, Shimizutani K, Furukawa S
  • Journal Title: Oral Oncol Volume: 48(5) Pages: 463-8
• [Presentation] 口腔癌原発巣の画像診断 (2012)
  • Author(s): Murakami S, Kakimoto N, Fuchihata H, Kishino M. ほか4件
  • Organizer: 第22回日本歯科医学会総会
  • Place of Presentation: Radiation therapy for tongue cancer
  • Year and Date: 2012-11-11
• [Presentation] Usefulness of radiation therapy (2012)
  • Author(s): Murakami S
  • Organizer: Special symposium at Paris KECO
  • Year and Date: 2012-06-18
• [Presentation] Usefulness of IDEAL in oral and maxillofacial MR imaging S (2012)
  • Author(s): MURAKAMI, Y. FUJINAMI, N. KAKIMOTO, H. SHIMAMOTO, M. KATAOKA, S. TOMITA, A. NAKATANI, Y. UCHIYAMA, T. SASAI, I. SUMIDA, T. TSUJIMOTO, S. FURUKAWA
  • Organizer: 13th ECDMFR
  • Year and Date: 2012-06-14
• [Presentation] 口腔癌に対する強度変調放射線治療の初期経験 (2012)
  • Author(s): 柿本直也、岡畑諒子、丸谷佳右、辻本友美、片岡観精、富田世紀、島本博彰、隅田伊織、中谷温紀、内山百夏、笹井正思、北森秀希、村上秀明、古川惣平
  • Organizer: 第53回日本歯科放射線学会総会・放射線治療懇話会
  • Year and Date: 2012-06-02
• [Book] お口の健康全身元気ー各世代の最新歯科医療ー (2013)
  • Author(s): 村上秀明
• [Book] 口腔癌とリンパ節の画像診断
  • Author(s): 村上秀明