Application of guided bone regeneration to the cultured artificial bone for the reconstraction of jaw

2014 Fiscal Year Final Research Report

• Project/Area Number: 23592823
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Prosthetic dentistry
• Research Institution: Hokkaido University
• Principal Investigator: OHORI Kotoha 北海道大学, 大学病院, 医員 (10374539)
• Co-Investigator(Kenkyū-buntansha): YOKOYAMA Atsurou 北海道大学, 大学院歯学研究科, 教授 (20210627) ; KOMATSUBARA Hiromi 北海道大学, 大学病院, 助教 (50221247) ; YAMAMOTO Satoru 北海道大学, 大学院歯学研究科, 助教 (10344524)
• Project Period (FY): 2011-04-28 – 2015-03-31
• Keywords: 培養人工骨 / ＧＢＲ法 / 骨形成

Outline of Final Research Achievements

This research sets 4 groups;the 1st group grafted the artificial bone, was cultured the bone marrow stem cells on the HAP block, the 2nd group applied guided bone regeneration(GBR) method to the cultured artificial bone, the 3rd group grafted the HAP block, and the 4th group applied GBR to the HAP block under the parietal bone of rat were investigated the effects. Extensive bone formation was observed in the 1st group in comparison with the 3rd group. Also, the efficacy of bone formation was observed in the application with GBR. It suggested that the cultured artificial bone and the application with GBR to it made possibly bone formation period shortnig.

Free Research Field

医歯薬学