2013 Fiscal Year Final Research Report
A base maintenance study to perform security and reliable cell treatment that used a human marrow origin mesenchymal cell.
Project/Area Number |
23592923
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Surgical dentistry
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Research Institution | Hiroshima University |
Principal Investigator |
OKAMOTO KOSEI 広島大学, 病院(歯), 病院助教 (40423371)
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Co-Investigator(Kenkyū-buntansha) |
KURIHARA Hidemi 広島大学, 医歯薬保健学研究院(歯), 教授 (40161765)
OKAMOTO Tetsuji 広島大学, 医歯薬保健学研究院(歯), 教授 (00169153)
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Project Period (FY) |
2011 – 2013
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Keywords | 歯学 / 再生医学 |
Research Abstract |
With a mesenchyma system stem cell (MSC) derived from establishment marrow, I examined it in a serum-free medium for embryonic stem cells. In CD90 (Thy-1), CD105 (Endogrlin) which was a marker gene of the MSC, and gene Oct3/4, Nanog where expression was accepted with an undifferentiated human embryonic stem cell, expression was recognized in the MSC of which condition that added FGF-1, FGF-2, LIF, activin A and heparin in POWEREDBY10 or hESF7 nutrient medium. In addition, expression was accepted in the MSC which I cultured in hESF9 and hESF10 nutrient medium equally. Possibility to become the index of the undifferentiation voltinism of the MSC was suggested.
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[Patent(Industrial Property Rights)] Basal Medium for ES culturing2011
Inventor(s)
岡本哲治、古江美保、浅島誠
Industrial Property Rights Holder
岡本哲治
Industrial Property Rights Type
特許、米国特許米国出願番号:10/584,371,国際出願番号:PCT/JP04/19818,米国特許番号:No. 7,923,245
Industrial Property Number
米国出願番号:10/584,371,国際出願番号:PCT/JP04/19818,米国特許番号:No. 7,923,245
Acquisition Date
2011-04-12
Overseas