2013 Fiscal Year Final Research Report

Gastric emptying rate in subjects with malocclusion examined by [13C] breath test

Research Project

Project/Area Number	23593023
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Orthodontic/Pediatric dentistry
Research Institution	Tokyo Medical and Dental University
Principal Investigator	FUKUYAMA Eiji 東京医科歯科大学, 歯学部, 非常勤講師 (60326064)
Co-Investigator(Kenkyū-buntansha)	SHIMAZAKI Kazuno (10420259) ONO Takashi (30221857)
Project Period (FY)	2011 – 2013
Keywords	胃排出機能
Research Abstract	Masticatory function is significantly lower in individuals with malocclusion than in those with normal occlusion. Although several studies suggest that masticatory function influences gastrointestinal digestive function, the relationship between malocclusion and gastrointestinal symptoms has not been studied extensively. We hypothesized that insufficient masticatory function would increase the functional burden of the stomach and have some influence on the gastrointestinal system. The purpose of this study was to investigate masticatory function and gastric emptying rate in subjects with malocclusion. Eleven healthy dentate female volunteers and eleven female patients with malocclusion underwent a 13C-acetate breath test with a liquid meal. Maximum 13CO2 exhalation time (Tmax) was compared statistically between both groups. The mean Tmax of the malocclusion group was significantly longer than that of the normal occlusion group.